Patents by Inventor Ruediger Alexowsky

Ruediger Alexowsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220326199
    Abstract: A method of unambiguous identification and authentication of products for the purpose of better recognition of product forgeries and controlling product piracy, including applying to/into the product an identification substance admixture which contains paramagnetic phases or identifying a product which contains an identification substance admixture containing paramagnetic phases and has an ESR fingerprint spectrum that permits unambiguous identification of the product. Such an ESR fingerprint spectrum is easily measurable, but can be copied or forged only with difficulty. The method relates to an individualizable “femto tag” for femto ledgers and forms an important interface for what are known as “Internet of Things” (IOT).
    Type: Application
    Filed: June 4, 2020
    Publication date: October 13, 2022
    Applicant: Evonik Operations GmbH
    Inventors: Norbert WINDHAB, Kevin BURTON, Paul Joseph SPENCER, Jessica MÜLLER-ALBERS, Andrea ENGEL, Peter NIEPOTH, Rüdiger ALEXOWSKY, Julia LYUBINA, Christoph BRÜCHER, Carsten DENTLER, Andreas KARAU
  • Patent number: 10113050
    Abstract: A powdery or granulated composition, containing: (a) a copolymer containing, in polymerized form, a C1- to C4-alkyl ester of acrylic or methacrylic acid and an alkyl(meth)acrylate monomer containing a tertiary amino group in an alkyl radical; (b) 0.5 to 10% by weight based on (a) of a dicarboxylic acid having 3 to 10 carbon atoms; and (c) 5 to 20% by weight based on (a) of a fatty monocarboxylic acid having 8 to 18 carbon atoms, where the composition contains at least by 30% by weight of (a), (b), and (c).
    Type: Grant
    Filed: July 30, 2009
    Date of Patent: October 30, 2018
    Assignee: Evonik Roehm GmbH
    Inventors: Erna Roth, Ruediger Alexowsky, Hans-Ulrich Petereit, Christian Meier
  • Patent number: 9284416
    Abstract: The present invention provides a process for converting a solid (meth)acrylate copolymer into a dispersed form by preparing an aqueous dispersion comprising the components (a) a (meth)acrylate copolymer which is composed of free-radical polymerized methyl methacrylate, ethylacrylate and a salt of 2-trimethylammoniumethyl methacrylate, present in solid form as a powder or as a granulate, (b) up to 50% by weight calculated on the (meth)acrylate copolymer (a) of a dispersing agent selected from the groups of (b) i) plasticizers in combination with emulsifiers and/or (b) ii) pharmaceutically acceptable carbohydrates having 6 to 18 carbon atoms with a functional group and (c) water by mixing the components (a), (b) and (c) to give a suspension which becomes an aqueous dispersion during the conversion of the solid (meth)acrylate copolymer into the dispersed form, characterized in that, the (meth)acrylate copolymer is converted into the dispersed form by means of the presence of the dispersing agent at a temperature
    Type: Grant
    Filed: November 16, 2009
    Date of Patent: March 15, 2016
    Assignee: Evonik Roehm GmbH
    Inventors: Erna Roth, Ruediger Alexowsky, Hans-Ulrich Petereit, Kathrin Nollenberger, Christian Meier
  • Patent number: 8765152
    Abstract: The invention relates to a pharmaceutical or nutraceutical formulation comprising a core, comprising an active pharmaceutical or nutraceutical ingredient, a penetration promoter and a bioavailability promoting agent, and a polymeric coating for the gastrointestinal targeted release of the active ingredient, characterized in that the bioavailability promoting agent is a pharmaceutically acceptable inhibitor of proteolytic enzymes, which increases the oral bioavailability of the active ingredient by a factor of at least five, compared to a corresponding formulation without the bioavailability promoting agent.
    Type: Grant
    Filed: February 25, 2010
    Date of Patent: July 1, 2014
    Assignee: Evonik Roehm GmbH
    Inventors: Rosario Lizio, Michael Gottschalk, Michael Damm, Norbert Windhab, Melanie Liefke, Guenter Schmitt, Erna Roth, Ruediger Alexowsky
  • Patent number: 8431157
    Abstract: The invention relates to a partly neutralized anionic (meth)acrylate copolymer consisting of radically polymerized units containing 25-95% by weight (meth)acrylic acid C1 to C4 alkylesters and 5-75% by weight (meth)acrylate monomer with an anionic group, wherein 0.1 to 25% contained anionic groups are neutralized by a base. Said invention is characterized in that said base is embodied in the form of an cationic organic base whose molecular weight is greater than 150. A medical form containing said partly neutralized anionic (meth)acrylate copolymer and the use of said partly neutralized anionic (meth)acrylate copolymer for producing a medical form rapidly releasing an active substance having a determined pH value are also disclosed.
    Type: Grant
    Filed: December 15, 2005
    Date of Patent: April 30, 2013
    Assignee: Evonik Roehm GmbH
    Inventors: Rosario Lizio, Hans-Ulrich Petereit, Erna Roth, Michael Damm, Ruediger Alexowsky
  • Publication number: 20120315334
    Abstract: The invention relates to a pharmaceutical or nutraceutical formulation comprising a core, comprising an active pharmaceutical or nutraceutical ingredient, a penetration promoter and a bioavailability promoting agent, and a polymeric coating for the gastrointestinal targeted release of the active ingredient, characterized in that the bioavailability promoting agent is a pharmaceutically acceptable inhibitor of proteolytic enzymes, which increases the oral bioavailability of the active ingredient by a factor of at least five, compared to a corresponding formulation without the bioavailability promoting agent.
    Type: Application
    Filed: February 25, 2010
    Publication date: December 13, 2012
    Applicant: Evonik Roehm GmbH
    Inventors: Rosario Lizio, Michael Gottschalk, Michael Damm, Norbert Windhab, Melanie Liefke, Guenter Schmitt, Erna Roth, Ruediger Alexowsky
  • Publication number: 20120208832
    Abstract: The present invention provides a process for converting a solid (meth)acrylate copolymer into a dispersed form by preparing an aqueous dispersion comprising the components (a) a (meth)acrylate copolymer which is composed of free-radical polymerized methyl methacrylate, ethylacrylate and a salt of 2-trimethylammoniumethyl methacrylate, present in solid form as a powder or as a granulate, (b) up to 50% by weight calculated on the (meth)acrylate copolymer (a) of a dispersing agent selected from the groups of (b) i) plasticizers in combination with emulsifiers and/or (b) ii) pharmaceutically acceptable carbohydrates having 6 to 18 carbon atoms with a functional group and (c) water by mixing the components (a), (b) and (c) to give a suspension which becomes an aqueous dispersion during the conversion of the solid (meth)acrylate copolymer into the dispersed form, characterized in that, the (meth)acrylate copolymer is converted into the dispersed form by means of the presence of the dispersing agent at a temperature
    Type: Application
    Filed: November 16, 2009
    Publication date: August 16, 2012
    Applicant: Evonik Roehm GmbH
    Inventors: Erna Roth, Ruediger Alexowsky, Hans-Ulrich Petereit, Kathrin Nollenberger, Christian Meier
  • Publication number: 20120093903
    Abstract: The invention relates to a powdery or granulated composition comprising at least by 30% by weight of a mixture of (a) a copolymer composed of polymerized units of C1- to C4-alkyl esters of acrylic or methacrylic acid and of alkyl(meth)acrylate monomers with a tertiary amino group in the alkyl radical and (b) 5 to 28% by weight based on (a) of a salt of a fatty monocarboxylic acid having 10 to 18 carbon atoms, and (c) 10 to 30% by weight based on (a) of fatty monocarboxylic acid having 8 to 18 carbon atoms and/or a fatty alcohol having 8 to 18 carbon atoms.
    Type: Application
    Filed: March 17, 2010
    Publication date: April 19, 2012
    Applicant: Evonik Roehm GmbH
    Inventors: Erna Roth, Ruediger Alexowsky, Hans-Ulrich Petereit, Christian Meier
  • Publication number: 20120093904
    Abstract: The invention relates to a coating composition for the coating or binding of pharmaceutically, nutraceutically or cosmetically active ingredients, comprising (a) an anionic polymeric material, and (b) one or more salts of saturated monocarboxylic acids having 6 to 22 carbon atoms, characterized in that the amount of the salts of the monocarboxylic acids in the composition corresponds to 3 to 50 mol percent of the amount of anionic groups in the polymeric material. The invention also relates to a process for preparing a dispersion out of the composition, as well as the use of said composition in enteric-coated solid dosage forms.
    Type: Application
    Filed: July 30, 2009
    Publication date: April 19, 2012
    Applicant: EVONIK ROEHM GMBH
    Inventors: Erna Roth, Ruediger Alexowsky, Hans-Ulrich Petereit
  • Publication number: 20120071565
    Abstract: A powdery or granulated composition, containing: (a) a copolymer containing, in polymerized form, a C1- to C4-alkyl ester of acrylic or methacrylic acid and an alkyl(meth)acrylate monomer containing a tertiary amino group in an alkyl radical; (b) 0.5 to 10% by weight based on (a) of a dicarboxylic acid having 3 to 10 carbon atoms; and (c) 5 to 20% by weight based on (a) of a fatty monocarboxylic acid having 8 to 18 carbon atoms, where the composition contains at least by 30% by weight of (a), (b), and (c).
    Type: Application
    Filed: July 30, 2009
    Publication date: March 22, 2012
    Applicant: EVONIK ROEHM GmbH
    Inventors: Erna Roth, Ruediger Alexowsky, Hans-Ulrich Petereit, Christian Meier
  • Publication number: 20090041842
    Abstract: The invention relates to a partly neutralised anionic (meth)acrylate copolymer consisting of radically polymerised units containing 25-95% by weight (meth)acrylic acid C1 to C4 alkylesters and 5-75% by weight (meth)acrylate monomer with an anionic group, wherein 0.1 to 25% contained anionic groups are neutralised by a base. Said invention is characterised in that said base is embodied in the form of an cationic organic base whose molecular weight is greater than 150. A medical form containing said partly neutralised anionic (meth)acrylate copolymer and the use of said partly neutralised anionic (meth)acrylate copolymer for producing a medical form rapidly releasing an active substance having a determined pH value are also disclosed.
    Type: Application
    Filed: December 15, 2005
    Publication date: February 12, 2009
    Applicant: Roehm GmbH
    Inventors: Rosario Lizio, Hans-Ulrich Petereit, Erna Roth, Michael Damm, Ruediger Alexowsky