Patents by Inventor Ruediger Streicher

Ruediger Streicher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED ARYLSULPHONYLGLYCINES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS
    Publication number: 20100093703
    Abstract: The present invention relates to substituted arylsulphonylglycines of general formula wherein R, R4, X, Y, Z and m are defined as in claim 1, the tautomers, enantiomers, diastereomers, mixtures thereof and salts thereof, which have valuable pharmacological properties, particularly the suppression of the interaction of glycogen phosphorylase a with the GL subunit of glycogen-associated protein phosphatase 1 (PP1), and their use as pharmaceutical compositions.
    Type: Application
    Filed: February 15, 2008
    Publication date: April 15, 2010
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Holger Wagner, Elke Langkopf, Ruediger Streicher, Matthias Eckhardt, Annette Schuler-Metz, Alexander Pautsch, Corinna Schoelch
  • CRYSTALLINE FORM OF 1' -(1-METHYLETHYL)-4' -[(2-FLUORO-4-METHOXYPHENYL)METHYL]-5' -METHYL-1H-PYRAZOL-3' -O-BETA-D-GLUCOPYRANOSIDE, A METHOD FOR ITS PREPARATION AND THE USE THEREOF FOR PREPARING MEDICAMENTS
    Publication number: 20090181905
    Abstract: The invention relates to a crystalline form of 1?-(1-methylethyl)-4?-[(2-fluoro-4-methoxyphenyl)methyl]-5?-methyl-1H-pyrazol-3?-O-?-D-glucopyranoside, to a method for the preparation thereof, as well as to the use thereof for preparing medicaments.
    Type: Application
    Filed: March 16, 2009
    Publication date: July 16, 2009
    Applicants: BOEHRINGER INGELHEIM INTERNATIONAL GMBH, AJINOMOTO CO., INC.
    Inventors: Gerd KRAEMER, Hans-Juergen MARTIN, Gebhard ADELGOSS, Klaus DUGI, Adil DURAN, Peter EICKELMANN, Steffen MAIER, Sabine PINNETTI, Regine RITTER, Gebhard SCHILCHER, Ruediger STREICHER, Leo THOMAS
  • Crystalline form of 1?-(1-methylethyl)-4?-[(2-fluoro-4-methoxyphenyl)methyl]-5?-methyl-1H-pyrazol-3?-O-?-D-glucopyranoside, a method for its preparation and the use thereof for preparing medicaments
    Patent number: 7524822
    Abstract: The invention relates to a crystalline form of 1?-(1-methylethyl)-4?-[(2-fluoro-4-methoxyphenyl)methyl]-5?-methyl-1H-pyrazol-3?-O-?-D-glucopyranoside, to a method for the preparation thereof, as well as to the use thereof for preparing medicaments.
    Type: Grant
    Filed: January 10, 2007
    Date of Patent: April 28, 2009
    Assignees: Boehringer Ingelheim International GmbH, Ajinomoto Co., Inc.
    Inventors: Gerd Kraemer, Hans-Juergen Martin, Gebhard Adelgoss, Klaus Dugi, Adil Duran, Peter Eickelmann, Steffen Maier, Sabine Pinnetti, Regine Ritter, Gebhard Schilcher, Ruediger Streicher, Leo Thomas
  • Crystalline form of 1'-(1-methylethyl)-4'-[(2-fluoro-4-methoxyphenyl)methyl]-5'-methyl-1H-pyrazol-3'-O-beta-D-glucopyranoside, a method for its preparation and the use thereof for preparing medicaments
    Publication number: 20070244176
    Abstract: The invention relates to a crystalline form of 1?-(1-methylethyl)-4?-[(2-fluoro-4-methoxyphenyl)methyl]-5?-methyl-1H-pyrazol-3?-O-?-D-glucopyranoside, to a method for the preparation thereof, as well as to the use thereof for preparing medicaments.
    Type: Application
    Filed: January 10, 2007
    Publication date: October 18, 2007
    Inventors: Gerd Kraemer, Hans-Juergen Martin, Gebhard Adelgoss, Klaus Dugi, Adil Duran, Peter Eickelmann, Steffen Maier, Sabine Pinnetti, Regine Ritter, Gebhard Schilcher, Ruediger Streicher, Leo Thomas
  • Methods for preventing and treating metabolic disorders and new pyrazole-O-glycoside derivatives
    Publication number: 20070072813
    Abstract: The invention relates to methods for preventing or treating metabolic disorders, for improving glycemic control, for preventing progression from impaired glucose tolerance, insulin resistance and/or from metabolic syndrome to type 2 diabetes mellitus, for preventing or treating of complications of diabetes mellitus, for reducing the weight, for preventing or treating the degeneration of pancreatic beta cells, for treating hyperinsulinemia and insulin resistance and diabetes type 1, in patients in need thereof by administering a pharmaceutical composition comprising a pyrazole-O-glycoside as defined in claim 1, or a prodrug thereof, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: July 28, 2006
    Publication date: March 29, 2007
    Inventors: Frank Himmelsbach, Roland Maier, Peter Eickelmann, Leo Thomas, Edward Barsoumian, Klaus Dugi, Sabine Pinnetti, Regine Ritter, Ruediger Streicher, Koichi Fujita, Toshihiro Hatanaka, Nozomu Ishida, Katsumi Maezono, Koji Ohsumi
  • Bicyclic oligopeptides
    Patent number: 7101848
    Abstract: The invention relates to a bicyclic oligopeptide or ester thereof having the capability to inhibit the glucagon receptor, comprised of: (a) a first cyclic group, which comprises at least one cysteine group and is formed by an amide bonding of the N-terminal amino acid with the second carboxylate group of a diacid amino acid, and (b) a second cyclic group which is formed by an amide bonding of an amino acid with the ?-carboxylate group of said diacid amino acid, and by a disulfide bonding of the C-terminal cysteine and a cysteine group within the first cyclic group (a); and to the use of such bicyclic oligopeptides for the preparation of a medicament for the treatment or prevention of diseases, in which glucagon receptors are involved.
    Type: Grant
    Filed: July 17, 2003
    Date of Patent: September 5, 2006
    Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Olivier Potterat, Ruediger Streicher, Klaus Wagner, Till Maurer, Juergen Mack, Stefan Peters
  • Cyanothiophenes, their preparation and their use in pharmaceutical compositions
    Publication number: 20060094764
    Abstract: The present invention relates to cyanothiophenes of general formula wherein the Rs are defined as in the claims, the tautomers, their stereoisomers, the mixtures thereof and the salts thereof, which have valuable pharmacological properties, particularly a glugacon receptor-antagonistic activity.
    Type: Application
    Filed: October 13, 2005
    Publication date: May 4, 2006
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Ralf Anderskewitz, Gerd Morschhaeuser, Ruediger Streicher, Thomas Trieselmann, Rainer Walter
  • Use of substituted 2 phenylbenzimidazoles as medicaments
    Publication number: 20050014810
    Abstract: The present invention relates to the use of a substituted 2-phenylbenzimidazole of formula I wherein R1, R2, R3, R4, R5 and m have the meanings given in the claims, for the preparation of a medicament for the treatment or prevention of diseases involving glucagon receptors, as well as new compounds of formula I wherein R1 is a group of formula
    Type: Application
    Filed: December 23, 2003
    Publication date: January 20, 2005
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Ruediger Streicher, Juergen Mack, Rainer Walter, Ingo Konetzki, Thomas Trieselmann, Volkhard Austel
  • Bicyclic oligopeptides
    Publication number: 20040072736
    Abstract: The invention relates to a bicyclic oligopeptide or ester thereof having the capability to inhibit the glucagon receptor, comprised of:
    Type: Application
    Filed: July 17, 2003
    Publication date: April 15, 2004
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Olivier Potterat, Ruediger Streicher, Klaus Wagner, Till Maurer, Juergen Mack, Stefan Peters