Abstract: A method for determining gaze location includes: providing a gaze tracking device including an illumination source to illuminate an eye of an observer at an angle of about 20 degrees to 40 degrees relative to a resting eye position of the eye, a camera or an imager includes at least one focusing lens, the camera or imager to acquire sequences of digital images of the eye, and a processor to run a gaze tracking process; and running the gaze tracking process to locate at least two Purkinje reflections of the illuminating source from the eye in the images. A gaze tracking system and a gaze tracking device are also described.

Abstract: A method for determining gaze location includes: providing a gaze tracking device including an illumination source to illuminate an eye of an observer at an angle of about 20 degrees to 40 degrees relative to a resting eye position of the eye, a camera or an imager includes at least one focusing lens, the camera or imager to acquire sequences of digital images of the eye, and a processor to run a gaze tracking process; and running the gaze tracking process to locate at least two Purkinje reflections of the illuminating source from the eye in the images. A gaze tracking system and a gaze tracking device are also described.

Abstract: The present invention utilizes multiphoton microscopy for a quantitative analysis of a bio tissue or a skin. Multiphoton microscopy is characterized in low invasion, low photo damage and high penetration. Hence, scanning through multiphoton microscopy does not hurt the bio tissue. It is thus fit for scanning live bio tissues to know its aging status. In addition, the quantitative analysis provides a precise index for diagnosing a damage severity of the tissue, like cancer.