Patents by Inventor Ruggero De Paulis
Ruggero De Paulis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11684472Abstract: A sizing tool for use in implanting a composite valved conduit having a prosthetic heart valve on a distal end attached to a conduit graft that extends to a proximal end. The tool includes a proximal handle and a distal shaft, a prosthetic heart valve sizer having an axis affixed to a distal end of the shaft, and a conduit graft replica having an axis mounted on the shaft proximal to the heart valve sizer. A method of securing a composite valved conduit includes introducing to an excised ascending aorta the sizing tool, measuring the aortic annulus with the prosthetic heart valve sizer, and determining whether the coronary arteries have sufficient length or whether an additional tubular coronary extension segment is required to add to one or both of the ends of the coronary arteries by extending the coronary arteries toward the conduit graft replica.Type: GrantFiled: January 13, 2020Date of Patent: June 27, 2023Assignee: EDWARDS LIFESCIENCES CORPORATIONInventors: Ruggero De Paulis, Michael C. Murad
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Publication number: 20210322169Abstract: An annuloplasty repair segment for heart valve annulus repair and a method for forming. A multi-stranded cable replaces solid core wire for both the tricuspid and mitral valves which allows for greater deployment flexibility for minimally-invasive surgical (MIS) implant, while still maintaining the required strength and similar tensile properties of solid-core wire. The particular shape of the annuloplasty ring is fixed using a heat setting process including heating the flexible core member to a temperature higher than 500° C. and holding it in a desired heat-set saddle shape for a period of time. The core is then rapidly cooled to impart physical properties such that the flexible core member can be straightened, during implantation, to fit through a tubular access device and regain the heat-set saddle shape after exiting the access device and, when attached to the native heart valve, the flexible core member is strong enough to remodel the native heart valve.Type: ApplicationFiled: June 28, 2021Publication date: October 21, 2021Inventors: John F. Migliazza, Ruggero De Paulis
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Patent number: 11045319Abstract: An annuloplasty repair segment for heart valve annulus repair and a method for forming. A multi-stranded cable replaces solid core wire for both the tricuspid and mitral valves which allows for greater deployment flexibility for minimally-invasive surgical (MIS) implant, while still maintaining the required strength and similar tensile properties of solid-core wire. The particular shape of the annuloplasty ring is fixed using a heat setting process including heating the flexible core member to a temperature higher than 500° C. and holding it in a desired heat-set saddle shape for a period of time. The core is then rapidly cooled to impart physical properties such that the flexible core member can be straightened, during implantation, to fit through a tubular access device and regain the heat-set saddle shape after exiting the access device and, when attached to the native heart valve, the flexible core member is strong enough to remodel the native heart valve.Type: GrantFiled: March 13, 2019Date of Patent: June 29, 2021Assignee: Edwards Lifesciences CorporationInventors: John F. Migliazza, Ruggero De Paulis
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Publication number: 20200146820Abstract: A sizing tool for use in implanting a composite valved conduit having a prosthetic heart valve on a distal end attached to a conduit graft that extends to a proximal end. The tool includes a proximal handle and a distal shaft, a prosthetic heart valve sizer having an axis affixed to a distal end of the shaft, and a conduit graft replica having an axis mounted on the shaft proximal to the heart valve sizer. A method of securing a composite valved conduit includes introducing to an excised ascending aorta the sizing tool, measuring the aortic annulus with the prosthetic heart valve sizer, and determining whether the coronary arteries have sufficient length or whether an additional tubular coronary extension segment is required to add to one or both of the ends of the coronary arteries by extending the coronary arteries toward the conduit graft replica.Type: ApplicationFiled: January 13, 2020Publication date: May 14, 2020Inventors: Ruggero De Paulis, Michael C. Murad
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Patent number: 10537430Abstract: A sizing tool for use in implanting a composite valved conduit having a prosthetic heart valve on a distal end attached to a conduit graft that extends to a proximal end. The tool includes a proximal handle and a distal shaft, a prosthetic heart valve sizer having an axis affixed to a distal end of the shaft, and a conduit graft replica having an axis mounted on the shaft proximal to the heart valve sizer. A method of securing a composite valved conduit includes introducing to an excised ascending aorta the sizing tool, measuring the aortic annulus with the prosthetic heart valve sizer, and determining whether the coronary arteries have sufficient length or whether an additional tubular coronary extension segment is required to add to one or both of the ends of the coronary arteries by extending the coronary arteries toward the conduit graft replica.Type: GrantFiled: December 18, 2017Date of Patent: January 21, 2020Assignee: Edwards Lifesciences CorporationInventors: Ruggero De Paulis, Michael C. Murad
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Publication number: 20190209321Abstract: An annuloplasty repair segment for heart valve annulus repair and a method for forming. A multi-stranded cable replaces solid core wire for both the tricuspid and mitral valves which allows for greater deployment flexibility for minimally-invasive surgical (MIS) implant, while still maintaining the required strength and similar tensile properties of solid-core wire. The particular shape of the annuloplasty ring is fixed using a heat setting process including heating the flexible core member to a temperature higher than 500° C. and holding it in a desired heat-set saddle shape for a period of time. The core is then rapidly cooled to impart physical properties such that the flexible core member can be straightened, during implantation, to fit through a tubular access device and regain the heat-set saddle shape after exiting the access device and, when attached to the native heart valve, the flexible core member is strong enough to remodel the native heart valve.Type: ApplicationFiled: March 13, 2019Publication date: July 11, 2019Inventors: John F. Migliazza, Ruggero De Paulis
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Patent number: 10265171Abstract: An annuloplasty repair segment for heart valve annulus repair. In one embodiment a multi-stranded cable replaces solid core wire for both the tricuspid and mitral valves. Cable allows for greater deployment flexibility for minimally-invasive surgical (MIS) implant, while still maintaining the required strength and similar tensile properties of solid-core wire. Stranded cable provides a MIS annuloplasty ring with sufficient flexibility in the x-y plane to allow a surgeon to squeeze the ring into a small incision, such as being able to pass through an 18 Fr or smaller catheter, while maintaining structural rigidity under forces exerted on the implanted ring by the cardiac cycle. The particular shape of the annuloplasty ring is fixed using a heat setting process.Type: GrantFiled: June 7, 2017Date of Patent: April 23, 2019Assignee: Edwards Lifesciences CorporationInventors: John F. Migliazza, Ruggero De Paulis
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Publication number: 20180104058Abstract: A sizing tool for use in implanting a composite valved conduit having a prosthetic heart valve on a distal end attached to a conduit graft that extends to a proximal end. The tool includes a proximal handle and a distal shaft, a prosthetic heart valve sizer having an axis affixed to a distal end of the shaft, and a conduit graft replica having an axis mounted on the shaft proximal to the heart valve sizer. A method of securing a composite valved conduit includes introducing to an excised ascending aorta the sizing tool, measuring the aortic annulus with the prosthetic heart valve sizer, and determining whether the coronary arteries have sufficient length or whether an additional tubular coronary extension segment is required to add to one or both of the ends of the coronary arteries by extending the coronary arteries toward the conduit graft replica.Type: ApplicationFiled: December 18, 2017Publication date: April 19, 2018Inventors: Ruggero De Paulis, Michael C. Murad
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Patent number: 9844436Abstract: A sizing tool for use in implanting a composite valved conduit having a prosthetic heart valve on a distal end attached to a conduit graft that extends to a proximal end. The tool includes a proximal handle and a distal shaft, a prosthetic heart valve sizer having an axis affixed to a distal end of the shaft, and a conduit graft replica having an axis mounted on the shaft proximal to the heart valve sizer. A method of securing a composite valved conduit includes introducing to an excised ascending aorta the sizing tool, measuring the aortic annulus with the prosthetic heart valve sizer, and determining whether the coronary arteries have sufficient length or whether an additional tubular coronary extension segment is required to add to one or both of the ends of the coronary arteries by extending the coronary arteries toward the conduit graft replica.Type: GrantFiled: October 24, 2013Date of Patent: December 19, 2017Assignee: Edwards Lifesciences CorporationInventors: Ruggero De Paulis, Michael C. Murad
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Publication number: 20170266004Abstract: An annuloplasty repair segment for heart valve annulus repair. In one embodiment a multi-stranded cable replaces solid core wire for both the tricuspid and mitral valves. Cable allows for greater deployment flexibility for minimally-invasive surgical (MIS) implant, while still maintaining the required strength and similar tensile properties of solid-core wire. Stranded cable provides a MIS annuloplasty ring with sufficient flexibility in the x-y plane to allow a surgeon to squeeze the ring into a small incision, such as being able to pass through an 18 Fr or smaller catheter, while maintaining structural rigidity under forces exerted on the implanted ring by the cardiac cycle. The particular shape of the annuloplasty ring is fixed using a heat setting process.Type: ApplicationFiled: June 7, 2017Publication date: September 21, 2017Inventors: John F. Migliazza, Ruggero De Paulis
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Patent number: 9687346Abstract: An annuloplasty repair segment for heart valve annulus repair. In one embodiment a multi-stranded cable replaces solid core wire for both the tricuspid and mitral valves. Cable allows for greater deployment flexibility for minimally-invasive surgical (MIS) implant, while still maintaining the required strength and similar tensile properties of solid-core wire. Stranded cable provides a MIS annuloplasty ring with sufficient flexibility in the x-y plane to allow a surgeon to squeeze the ring into a small incision, such as being able to pass through an 18 Fr or smaller catheter, while maintaining structural rigidity under forces exerted on the implanted ring by the cardiac cycle. The particular shape of the annuloplasty ring is fixed using a heat setting process.Type: GrantFiled: February 25, 2014Date of Patent: June 27, 2017Assignee: Edwards Lifesciences CorporationInventors: John F. Migliazza, Ruggero De Paulis
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Publication number: 20140277420Abstract: An annuloplasty repair segment for heart valve annulus repair. In one embodiment a multi-stranded cable replaces solid core wire for both the tricuspid and mitral valves. Cable allows for greater deployment flexibility for minimally-invasive surgical (MIS) implant, while still maintaining the required strength and similar tensile properties of solid-core wire. Stranded cable provides a MIS annuloplasty ring with sufficient flexibility in the x-y plane to allow a surgeon to squeeze the ring into a small incision, such as being able to pass through an 18Fr or smaller catheter, while maintaining structural rigidity under forces exerted on the implanted ring by the cardiac cycle. The particular shape of the annuloplasty ring is fixed using a heat setting process.Type: ApplicationFiled: February 25, 2014Publication date: September 18, 2014Applicant: Edwards Lifesciences CorporationInventors: John F. Migliazza, Ruggero De Paulis
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Publication number: 20140121764Abstract: A sizing tool for use in implanting a composite valved conduit having a prosthetic heart valve on a distal end attached to a conduit graft that extends to a proximal end. The tool includes a proximal handle and a distal shaft, a prosthetic heart valve sizer having an axis affixed to a distal end of the shaft, and a conduit graft replica having an axis mounted on the shaft proximal to the heart valve sizer. A method of securing a composite valved conduit includes introducing to an excised ascending aorta the sizing tool, measuring the aortic annulus with the prosthetic heart valve sizer, and determining whether the coronary arteries have sufficient length or whether an additional tubular coronary extension segment is required to add to one or both of the ends of the coronary arteries by extending the coronary arteries toward the conduit graft replica.Type: ApplicationFiled: October 24, 2013Publication date: May 1, 2014Applicant: EDWARDS LIFESCIENCES CORPORATIONInventors: Ruggero De Paulis, Michael C. Murad
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Publication number: 20130150958Abstract: A device for repair of heart valves, and more particularly an improved annuloplasty band which is constituted by a semirigid open band includes a sheath and a generally curved stiffening semirigid element disposed within the sheath which extends from a first end adjacent the antero-lateral trigone to a second end adjacent the postero-medial trigone defining a non flat (not coplanar) compound C-curve shape so as to mime both in anterior and posterior side a saddle shape.Type: ApplicationFiled: August 2, 2010Publication date: June 13, 2013Inventor: Ruggero De Paulis
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Publication number: 20070135795Abstract: Device for placement in the thoracic cavity of a patient. The device is a cannula, tube or catheter for pericardial drainage and serves as a conduit for drainage of excessive fluid in the pericardial cavity to a receptacle outside the body. The device is placed in the pericardial cavity at the time of surgery and is used for drainage of fluid collection that is formed at a later stage when all other drainage tubes have been already removed or are clogged by organic material. The device incorporates a system for preventing that any clog or material might close all fenestrations that are present in the tube at a plurality of sites.Type: ApplicationFiled: October 30, 2006Publication date: June 14, 2007Inventor: Ruggero De Paulis
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Patent number: 6352554Abstract: A prosthetic aortic conduit for replacing a root portion of an aorta is provided. The conduit comprises a first tubular portion and a second tubular portion which are connected together along a substantially common axis. The second tubular portion does not substantially deform in a longitudinal direction and has resilient means which allow said second portion to be expandable in a lateral direction. This second portion is able to deform laterally to mimic the function of the sinuses of Valsalva. The method of manufacturing such a conduit comprises the steps of: a) providing a first tubular conduit suitable for use in heart surgery and having a longitudinal axis and first resilient means allowing some expansion in the longitudinal direction only; b) securing to one of the ends of this first conduit a second tubular conduit suitable for use in heart surgery, this second conduit having second resilient means which allows some expansion in the lateral direction only.Type: GrantFiled: April 29, 1999Date of Patent: March 5, 2002Assignee: Sulzer Vascutek LimitedInventor: Ruggero De Paulis
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Publication number: 20010049553Abstract: A prosthetic aortic conduit for replacing a root portion of an aorta is provided. The conduit comprises a first tubular portion and a second tubular portion which are connected together along a substantially common axis. The second tubular portion does not substantially deform in a longitudinal direction and has resilient means which allow said second portion to be expandable in a lateral direction. This second portion is able to deform laterally to mimic the function of the sinuses of Valsalva.Type: ApplicationFiled: April 29, 1999Publication date: December 6, 2001Applicant: ALLAN RATNERInventor: RUGGERO DE PAULIS