Patents by Inventor Rui Fen, Annabelle Lim

Rui Fen, Annabelle Lim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Prevention of Pertussis Using Adenylate Cyclase Deficient Bordetella Strains
    Publication number: 20180339035
    Abstract: A CyaA-deficient B. pertussis mutant was constructed and used in a vaccine. The pertussis-specific antibody profile and Th17 response induced by vaccination with the mutant was surprisingly comparable to that induced by B. pertussis strains not deficient in CyaA.
    Type: Application
    Filed: July 12, 2018
    Publication date: November 29, 2018
    Inventors: Sylvie Claudette Alonso, Rui Fen, Annabelle Lim, Camille Locht
  • Prevention of using adenylate cyclase deficient strains
    Patent number: 10046044
    Abstract: A CyaA-deficient B. pertussis mutant was constructed and used in a vaccine. The pertussis-specific antibody profile and Th17 response induced by vaccination with the mutant was surprisingly comparable to that induced by B. pertussis strains not deficient in CyaA.
    Type: Grant
    Filed: April 3, 2017
    Date of Patent: August 14, 2018
    Assignees: National University of Singapore, Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur de Lille
    Inventors: Sylvie Claudette Alonso, Rui Fen Annabelle Lim, Camille Locht
  • Prevention of Pertussis Using Adenylate Cyclase Deficient Bordetella Strains
    Publication number: 20170202944
    Abstract: A CyaA-deficient B. pertussis mutant was constructed and used in a vaccine. The pertussis-specific antibody profile and Th17 response induced by vaccination with the mutant was surprisingly comparable to that induced by B. pertussis strains not deficient in CyaA.
    Type: Application
    Filed: April 3, 2017
    Publication date: July 20, 2017
    Inventors: Sylvie Claudette Alonso, Rui Fen, Annabelle Lim, Camille Locht
  • Adenylate cyclase deficient bordetella strains
    Patent number: 9655959
    Abstract: A CyaA-deficient B. pertussis mutant was constructed and used in a vaccine. The pertussis-specific antibody profile and Th17 response induced by vaccination with the mutant was surprisingly comparable to that induced by B. pertussis strains not deficient in CyaA.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: May 23, 2017
    Assignees: National University of Singapore, Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur de Lille
    Inventors: Sylvie Claudette Alonso, Rui Fen Annabelle Lim, Camille Locht
  • Adenylate Cyclase Deficient Bordetella Strains
    Publication number: 20160095914
    Abstract: A CyaA-deficient B. pertussis mutant was constructed and used in a vaccine. The pertussis-specific antibody profile and Th17 response induced by vaccination with the mutant was surprisingly comparable to that induced by B. pertussis strains not deficient in CyaA.
    Type: Application
    Filed: September 30, 2015
    Publication date: April 7, 2016
    Inventors: Sylvie Claudette Alonso, Rui Fen, Annabelle Lim, Camille Locht