Patents by Inventor Rui-Rong Yuan

Rui-Rong Yuan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treating inflammatory disorders and traumatic brain injury using stabilized non-hematopoietic EPO short peptides
    Patent number: 11559565
    Abstract: The described invention provides methods for treating an inflammatory brain disease, disorder or condition and for treating a traumatic brain injury having an inflammatory component in a subject in need thereof using isolated erythropoietin (EPO)-derived oligopeptides.
    Type: Grant
    Filed: June 5, 2020
    Date of Patent: January 24, 2023
    Assignees: United States Government As Represented By The Department of Veterans Affairs, Rutgers, The State University of New Jersey
    Inventors: Peter C. Dowling, Bo Wang, Rui Rong Yuan, Wei Lu
  • Methods For Treating Inflammatory Disorders and Traumatic Brain Injury Using Stabilized Non-Hematopoietic EPO Short Peptides
    Publication number: 20200376079
    Abstract: The described invention provides methods for treating an inflammatory brain disease, disorder or condition and for treating a traumatic brain injury having an inflammatory component in a subject in need thereof using isolated erythropoietin (EPO)-derived oligopeptides.
    Type: Application
    Filed: June 5, 2020
    Publication date: December 3, 2020
    Inventors: Peter C. Dowling, Bo Wang, Rui Rong Yuan, Wei Lu
  • Methods for treating inflammatory disorders and traumatic brain injury using stabilized non-hematopoietic EPO short peptides
    Patent number: 9345745
    Abstract: The described invention provides methods for treating an inflammatory brain disease, disorder or condition and for treating a traumatic brain injury having an inflammatory component in a subject in need thereof using isolated erythropoietin (EPO)-derived oligopeptides.
    Type: Grant
    Filed: March 28, 2011
    Date of Patent: May 24, 2016
    Inventors: Bo Wang, Rui Rong Yuan, Wei Lu, Peter C. Dowling
  • ERYTHROPOIETIN-DERIVED SHORT PEPTIDE AND ITS MIMICS AS IMMUNO/INFLAMMATORY MODULATORS
    Publication number: 20150018274
    Abstract: The present invention provides isolated stabilized EPO-derived peptides and their mimics that protect against tissue damage in subjects having diverse forms of neural and non-neural organ system injury, pharmaceutical compositions containing the isolated stabilized EPO-derived peptides, methods for treating symptoms of a disease, disorder or condition having an inflammatory or an autoimmune component in a subject in need thereof, and methods for downregulating immune mediator activity in a subject in need thereof.
    Type: Application
    Filed: January 23, 2014
    Publication date: January 15, 2015
    Applicant: UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY
    Inventors: Yasuhiro Maeda, Rui Rong Yuan, Joseph Menonna, Wei Ping Li, Peter Dowling
  • Erythropoietin-derived short peptide and its mimics as immuno/inflammatory modulators
    Patent number: 8653028
    Abstract: The present invention provides isolated stabilized EPO-derived peptides and their mimics that protect against tissue damage in subjects having diverse forms of neural and non-neural organ system injury, pharmaceutical compositions containing the isolated stabilized EPO-derived peptides, methods for treating symptoms of a disease, disorder or condition having an inflammatory or an autoimmune component in a subject in need thereof, and methods for downregulating immune mediator activity in a subject in need thereof.
    Type: Grant
    Filed: May 1, 2006
    Date of Patent: February 18, 2014
    Inventors: Rui Rong Yuan, Wei Ping Li, Yasuhiro Maeda, Peter Dowling
  • METHODS FOR TREATING INFLAMMATORY DISORDERS AND TRAUMATIC BRAIN INJURY USING STABILIZED NON-HEMATOPOIETIC EPO SHORT PEPTIDES
    Publication number: 20110190217
    Abstract: The described invention provides methods for treating an inflammatory brain disease, disorder or condition and for treating a traumatic brain injury having an inflammatory component in a subject in need thereof using isolated erythropoietin (EPO)-derived oligopeptides.
    Type: Application
    Filed: March 28, 2011
    Publication date: August 4, 2011
    Inventors: Bo Wang, Rui Rong Yuan, Wei Lu, Peter C. Dowling
  • ERYTHROPOIETIN-DERIVED SHORT PEPTIDE AND ITS MIMICS AS IMMUNO/INFLAMMATORY MODULATORS
    Publication number: 20090029906
    Abstract: The present invention provides isolated stabilized EPO-derived peptides and their mimics that protect against tissue damage in subjects having diverse forms of neural and non-neural organ system injury, pharmaceutical compositions containing the isolated stabilized EPO-derived peptides, methods for treating symptoms of a disease, disorder or condition having an inflammatory or an autoimmune component in a subject in need thereof, and methods for downregulating immune mediator activity in a subject in need thereof.
    Type: Application
    Filed: May 1, 2006
    Publication date: January 29, 2009
    Applicant: UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY
    Inventors: Rui Rong Yuan, Wei Ping Li, Joseph Menonna, Yasuhiro Maeda, Peter Dowling
  • Suicide tetramers and uses thereof
    Publication number: 20030228258
    Abstract: The present invention provides a cytotoxic MHC I conjugate comprising a cytotoxic moiety, biotinylated MHC I monomers which each comprise an antigenic peptide and streptavidin, bound to the cytotoxic moiety or to a biotinylated cytotoxic moiety and to the biotinylated MHC I monomers. Alternative constructs comprising a cytotoxic moiety and biotinylated MHC I monomers where each monomer comprises an antibody fragment also are provided. The cytotoxic moiety may comprise an 225Ac radionuclide or other cytotoxin. Further provided are methods of killing CD8+T cell clonal populations.
    Type: Application
    Filed: May 30, 2003
    Publication date: December 11, 2003
    Inventors: David Scheinberg, Michael McDevitt, Rui-Rong Yuan