Abstract: Provided herein is a pharmaceutical composition comprising an effective amount of cypate-Cyclo(Cys-Gly-Arg-Asp-Ser-Pro-Cys)-Lys-OH (LS301), cypate-Cyclo(Cys-Gly-Arg-Asp-Ser-Pro-Cys)-Tyr-OH (LS838) or pharmaceutically acceptable salts thereof, wherein each amino acid residue is independently in a D or L configuration; a divalent metal ion; and a pharmaceutically acceptable carrier. Further provided are lyophilized products comprising a dye-conjugate and m methods for identifying compromised and for binding phosphorylated annexin A2 (pANXA2) protein in a biological sample using a composition described herein.

Abstract: The present invention provides a compound as represented by formula I, or a pharmaceutically acceptable salt or ester, a prodrug, an optical isomer, a stereoisomer, or a solvate thereof. The compound provided by the present invention can be used for preparing drugs for preventing or treating hypertension, or hypertension-related diseases, or pulmonary hypertension, or pulmonary hypertension-related diseases. The compound provided by the present invention has a different mechanism from existing drugs for treating hypertension and pulmonary hypertension, thereby laying a new material foundation for the development of drugs for treating hypertension and pulmonary hypertension.

Abstract: A fault detection method includes: obtaining a scheduling table of a target task, where the scheduling table is used to indicate at least one test pattern, the at least one test pattern is used to detect a fault in a target logic circuit, and the target logic circuit is a logic circuit configured to execute the target task; and executing the at least one test pattern based on the scheduling table, to detect the fault in the target logic circuit.

Abstract: The present disclosure relates to an auxiliary device and auxiliary method for epidural anesthesia needle placement, the auxiliary device comprising: a needle placement unit (1), a motion guide unit (2) for driving the needle placement unit into movement, and a control unit (3) for supporting and controlling the motion guide unit (2), the needle placement unit (1) being electrically connected to the control unit (3); the needle placement unit (1) comprises: a first support (11) connected to the motion guide unit (2), a second support (12) slidably connected with the first support (11), a needle placement assembly (13) slidably connected with the second support (12), and a first drive (14) arranged on the first support (11) for driving the second support (12) into motion. The scheme of the present disclosure may perform a real-time multidimensional monitoring to the puncture process, achieving autonomous, precise, safe needle placement and puncture operations.

Abstract: Disclosed is a multi-modal and multi-degree-of-freedom piezoelectric active vibration isolation platform and a working method therefor. The piezoelectric active vibration isolation platform includes an upper platform, a lower platform, a control module, and four vibration isolation modules, where the vibration isolation module includes a passive vibration isolation unit and an active vibration isolation unit; the passive vibration isolation unit includes an upper connector, a lower connector, a cross Hooke hinge, and a first acceleration sensor; the active vibration isolation unit includes a fixed beam, a pre-tightening bolt, a second acceleration sensor, and a driving component; the platform can provide active vibration isolation for the longitudinal (axial) vibration and the bending vibration in any radial direction of a vibration isolation object, and has the advantages of fast response, resistance to electromagnetic interference, and light weight.

Abstract: A processing method includes obtaining input information from an input member of an electronic apparatus. The input information includes a behavior parameter in a process of inputting a target word. The method further includes determining a display parameter of the target word based on the behavior parameter to display the target word on a target display according to the display parameter. The display parameter represents feature information when inputting the target word.

Abstract: In various examples, multilabel hierarchical classification of objects for autonomous systems and applications is described herein. Systems and methods are disclosed that use one or more neural networks to classify objects, such as traffic signs, using multilabel classification and/or hierarchical classification. For instance, a multilabel subnetwork of the neural network(s) may classify an object based at least on one or more attributes associated with the object. As such, the output from the multilabel subnetwork may include at least a classification associated with the object and an attribute classification(s) associated with the object. A hierarchical subnetwork of the neural network(s) may also classify the object using one or more class labels, where a class label indicates another classification and/or a class group associated with the object.

Abstract: Provided are a negative electrode plate and a preparation method thereof, a battery cell, a battery, and an electrical device. The negative electrode plate includes a current collector and a film layer disposed on the current collector. The film layer includes a first part and a second part disposed along a thickness direction of the film layer. The first part is disposed on the current collector. The second part is disposed on the first part. The first part includes a first active material. The second part includes a second active material. The first active material includes a first carbon-based material. The second active material includes a second carbon-based material containing a coating layer. A powder compaction density of the first active material is greater than a powder compaction density of the second active material.

Abstract: A method includes displaying a list interface including a first container prop that contains a first pet virtual character and a second container prop that does not contain a pet virtual character. The method further includes, in response to a touch selection operation corresponding to selecting one of the first container prop or the second container prop, displaying an aiming interface corresponding to the selected one of the first container prop or the second container prop and displaying an aiming sight. The method further includes, in response to a touch aiming operation on the aiming interface, adjusting a position of the displayed aiming sight. The method further includes, when the first container prop is selected, displaying throwing the first pet virtual character in response to a touch throwing operation, and when the second container prop is selected, displaying throwing the second container prop in response to the touch throwing operation.

Abstract: The present invention provides synthetic nucleic acid sequences comprising 10-30 nucleotides of the J2L and B6R gene regions and/or the 3? non-coding region of the Monkeypox virus genome, and a synthetic nucleic acid sequence comprising 10-30 nucleotides of a nucleic acid sequence that is complementary to at least one of those regions. Also provided are compositions comprising the sequences, and uses of the sequences in diagnostic kits. The present invention further provides a primer and probe set for determining the presence or absence of Monkeypox virus in a biological sample, wherein the primer set comprises at least one of the synthetic nucleic acid sequences. Also provided are a composition comprising the primer and probe set, and use of the primer and probe set in a diagnostic kit. Finally, the present invention provides kits and methods for determining the presence or absence of Monkeypox virus in a biological sample.

Abstract: The present application discloses a secondary battery, an apparatus including the secondary battery, artificial graphite and a method for the preparation thereof. The secondary battery includes a negative electrode plate including a negative active material, wherein the negative active material includes an artificial graphite having a numerical particle size Dn10 of at least 1 ?m; the artificial graphite has a graphitization degree of 90% to 95%; and the negative electrode plate has an OI value of at most 15, wherein the OI value of the negative electrode plate represents a ratio C004/C110, in which C004 is the peak area of the diffraction peak of 004 crystal plane of the artificial graphite in the negative electrode plate and C110 is the peak area of the diffraction peak of 110 crystal plane of the artificial graphite in the negative electrode plate.

Abstract: Provided herein is a pharmaceutical composition comprising an effective amount of cypate-Cyclo(Cys-Gly-Arg-Asp-Ser-Pro-Cys)-Lys-OH (LS301), cypate-Cyclo(Cys-Gly-Arg-Asp-Ser-Pro-Cys)-Tyr-OH (LS838) or pharmaceutically acceptable salts thereof, wherein each amino acid residue is independently in a D or L configuration; a divalent metal ion; and a pharmaceutically acceptable carrier. Further provided are lyophilized products comprising a dye-conjugate and m methods for identifying compromised and for binding phosphorylated annexin A2 (pANXA2) protein in a biological sample using a composition described herein.

Abstract: The present invention relates to a low-cost, thermally reversible valve for paper-fluidic diagnostic devices. In particular, this invention demonstrates a tunable valve mechanism fabricated by wax-ink printing and localized heating via thin-film resistors to sequentially release liquids through a cellulose or nitrocellulose membrane. The wax-ink valve can obstruct fluid flow for a sustained time and are thermally actuated to release a controlled amount of liquid past the valve. This integrated paper-fluidic diagnostic assay device requires minimal user involvement, can be easily manufactured and tuned to meet various fluid delivery timing and incubation needs.

Abstract: This application relates to signal processing methods and apparatuses. An example method includes generating a physical layer protocol data unit (PPDU) and sending the PPDU. The PPDU includes a first field, and the first field includes M sequences. The M sequences include a first sequence, a second sequence, a third sequence, and a fourth sequence. A partial sequence in the first sequence, a partial sequence in the second sequence, a partial sequence in the third sequence, and a partial sequence in the fourth sequence are determined based on Golay complementary sequences.

Abstract: The present disclosure provides a multiplication and accumulation circuit based on radix-4 booth code and differential weight storage. The circuit includes an input data encoding circuit, a differential weight storage circuit, an integral calculation circuit and a differential ADC circuit. The input data encoding circuit is configured to encode original input data. The differential weight storage circuit is configured to store weight values, and multiply the original input data after being encoded by the weight values stored to obtain multiplication results. The integral calculation circuit is configured to respectively accumulate a positive value and a negative value of each multiplication result. The differential ADC circuit is configured to perform analog-to-digital conversion on a difference between accumulated results of the positive values and the negative values to obtain a digital multiplication and accumulation result.

Abstract: The present application provides a secondary battery, an electrolyte, and an apparatus including the secondary battery. The secondary battery of the present application includes an electrolyte, characterized in that the electrolyte includes an organic solvent, and the organic solvent includes a cyclic carbonate and a chain carbonate; the mass ratio of the cyclic carbonate and the chain carbonate is from 25:75 to 32:68; the chain carbonate includes dimethyl carbonate; the mass percentage of the dimethyl carbonate in the chain carbonate is greater than or equal to 9 wt % and less than 50 wt %; wherein based on the total mass of the organic solvent, the mass percentage of a carboxylic acid ester is less than 5 wt %. The secondary battery of the present application can simultaneously obtain excellent low-temperature power, long service life and cycle performance.

Abstract: The present application discloses an artificial graphite, a preparation method therefor and the use thereof. A method for preparing an artificial graphite of an embodiment of the present application comprises the following step: subjecting a graphite raw material to a heat treatment to obtain the artificial graphite, wherein an environmental atmosphere for the heat treatment is at least one gas of air and carbon dioxide or a mixed gas of at least one gas of air and carbon dioxide and a chemically inert gas; and during the heat treatment, the graphite raw material is in a static state. The method realizes at least modifying a surface of the graphite raw material by controlling the heat treatment conditions for the graphite raw material, such that the prepared artificial graphite has an appropriately low compaction rebound capacity, a high and stable compacted density, and a good cycling performance.

Abstract: In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, the disclosure, in one aspect, relates to compounds and methods for activating NAMPT in a subject. The compounds described herein are useful in treating a neurological disorder, disease, or condition. In another aspect, compounds described herein are useful in treating metabolic disorders and diabetes.

Abstract: A preparation method of an artificial graphite includes heat-treating a graphite raw material to obtain artificial graphite, where an ambient atmosphere of the heat treatment is a mixed gas including a gas that is at least one of oxygen or water vapor and including a chemically inert gas, and, during the heat treatment, the graphite raw material is in a motion state.

Abstract: This application discloses a secondary battery including a positive electrode plate and a negative electrode plate, wherein the positive electrode plate comprises a positive electrode current collector and a positive electrode film disposed on a surface of the positive electrode current collector and comprising a positive active material, the negative electrode plate comprises a negative electrode current collector and a negative electrode film disposed on a surface of the negative electrode current collector and comprising a negative active material. The positive active material comprises one or more of lithium-containing phosphates with olivine structure and modified compounds thereof, and a resistance R of the negative electrode plate satisfies: 3.0 m??R?7.0 m?.