Abstract: The present disclosure discloses a B7H6 antibody and use thereof. The antibody includes heavy chain CDR1, heavy chain CDR2 and heavy chain CDR3; and light chain CDR1, light chain CDR2 and light chain CDR3. The antibody of the present disclosure is capable of binding to B7H6, and promoting the binding of B7H6 to the NK cell activating receptor NKp30, with an anti-cancer function.

Abstract: Disclosed is an antibody and use thereof. The antibody or antigen binding fragment includes CDR sequences selected from at least one of heavy-chain variable region CDR sequences: SEQ ID NOs: 1-3; and light-chain variable region CDR sequences: SEQ ID NOs: 4-6. The antibody prepared by the present disclosure can effectively bind to the ?3 domain of MICA or MICB, and further, promote the binding of NKG2D to MICA and/or MICB, and can effectively treat or prevent related diseases mediated by MICA and/or MICB, such as promoting the killing of tumors by NK cell.

Abstract: Provided are a bispecific antibody and use thereof. The recombinant antibody includes: a CDR Sequence selected from at least one of CD3 antibody variable region CDR sequences: SEQ ID NO: 1 to SEQ ID NO: 6, and B7H6 antibody variable region CDR sequences: SEQ ID NO: 7 to SEQ ID NO: 12; or an amino acid sequence having at least 95% identity thereto. The recombinant antibodies prepared according to the present application can simultaneously target CD3 and B7H6 antigens, and they have a. significantly prolonged half-life, exhibiting a stronger tumor-inhibiting ability than single-target antibodies.

Abstract: Air cleaner assemblies, components, and features are described. The features can be used to provide that the air cleaner assembly includes a housing and cover within which a filter cartridge having a media pack and a seal arrangement surrounding the media pack can be installed. The air cleaner assembly may also include a projection-receiver arrangement in which the filter cartridge has at least one first member and the housing has at least one second member that interacts with the first member. In one example, a portion of the seal arrangement is coplanar with the first member and a portion that is below the first member such that the first member is located between the seal arrangement and an inlet end of the filter cartridge.

Abstract: Disclosed are a battery connecting piece, a top cover assembly and a lithium battery. The battery connecting piece includes a first current collector and a second current collector, the first current collector is connected to the second current collector in a rotatable manner, the first current collector is configured to be connected to a top cover of a battery, the second current collector is configured to weld a tab of a cell, and an extension direction of a central axis of the second current collector rotating relative to the first current collector is perpendicular to a plane where the top cover is located in a state that the first current collector is connected to the top cover. The battery connecting piece drives the tab to fold more smoothly to prevent the tab from being torn, a bending precision of the tab is improved, and a product consistency is improved.

Abstract: An advanced map matching algorithm is disclosed, which embeds the road topology inherently in a set of path candidates. Road connectivity is maintained even in special situations such as U-turns, reverse driving, and tunnels. Careful path candidate management is designed to reduce the candidate count while preserving well-matching candidates. Paths are treated and evaluated independently using multiple criteria, which makes the algorithm reliable and robust in different scenarios.

Abstract: Various embodiments of the teachings herein include an environment prediction method based on a target available model. An example method comprises: generating a training sample based on predetermined environment data; using the training sample to perform training based on a fluid dynamics model and a Gaussian simulation model, to obtain a target available model; and based on real environment data, using the target available model to determine a real environment prediction value of a time-related pollution concentration sequence for a calibration position.

Abstract: Air cleaner assemblies, components, and features are described. The features can be used to provide that the air cleaner assembly includes a housing and cover within which a filter cartridge having a media pack and a seal arrangement surrounding the media pack can be installed. The air cleaner assembly may also include a projection-receiver arrangement in which the filter cartridge has at least one first member and the housing has at least one second member that interacts with the first member. In one example, a portion of the seal arrangement is coplanar with the first member and a portion that is below the first member such that the first member is located between the seal arrangement and an inlet end of the filter cartridge.

Abstract: The present invention provides an STPA method and apparatus for accurate identification of a loss scenario. The method comprises: defining the purpose of the analysis, comprising identifying of a loss; modeling a system state machine using a finite state machine; identifying an unsafe control action using the identified loss and the modeled system state machine. The method according to the present invention achieves accurate and efficient identification of loss scenarios of a complex system using state machines and model checking techniques.

Abstract: An advanced map matching algorithm is disclosed, which embeds the road topology inherently in a set of path candidates. Road connectivity is maintained even in special situations such as U-turns, reverse driving, and tunnels. Careful path candidate management is designed to reduce the candidate count while preserving well-matching candidates. Paths are treated and evaluated independently using multiple criteria, which makes the algorithm reliable and robust in different scenarios.

Abstract: A laser cutting method includes a step of determining a material to be removed and dividing the material to be removed into a plurality of material chips so as thereby to organize a machining plan for laser cutting; and, a step of, according to the machining plan for laser cutting, moving a laser along a boundary defining the material to be removed on the workpiece to perform cutting in a first direction and a second direction, such that the material chips can be separated from the workpiece orderly piece by piece so as to form a specific pattern. While in laser cutting, the method removes the material piece by piece. With the laser to remove the material chips through cutting along the boundary, the pattern on the workpiece is thus finished equivalently by the laser. Thereupon, the machining time can be significantly reduced.

Abstract: Provided is an antibody or antibody fragment. The antibody or the antibody fragment includes HCDR1 selected from GYTFSSFS, GYTFSTFA, or GYSFTAYT, HCDR2 selected from ILPGSNST, ILPGINNT, ILPGGNNT, or INPYNGGT, and HCDR3 selected from SSYWFAY, STYWFAY, or AREGNYYGSRGDFDY; and LCDR1 selected from QSLLNSGNQKNY or QTIVTN, LCDR2 selected from GAS or YAS, and LCDR3 selected from QNAHSYPPT, QNAHSYPPA, or QQSHSWPFT. The provided antibody can be used for treating cancer.

Abstract: Provided are a method for manufacturing a PDLC membrane electrode, a negative pressure platform, and a PDLC membrane. The method for manufacturing a PDLC membrane electrode includes the following steps: placing a PDLC membrane on a negative pressure platform with a side to be processed facing upwards, and making a liquid crystal activation area of the side to be processed of the PDLC membrane coincide with a transparent area of the negative pressure platform, and other area coincides with a main body area of the negative pressure platform; activating a liquid crystal layer of the PDLC membrane; cutting and tearing off, according to a half-cut area, a PET layer and an electric conduction layer located on the liquid crystal layer, and sweeping or tearing off the activated liquid crystal layer together to expose the electric conduction layer below the liquid crystal layer to form a corresponding electrode.

Abstract: Disclosed is an all-electric fixed underfloor wheel sets lathe, comprising: a frame, two rails provided on the frame, two lathe tools provided on the frame and two sets of wheel driving devices provided on the frame, wherein each set of the wheel driving devices comprises leveling brackets, drive assemblies provided on the leveling brackets, lifting assemblies provided on the leveling brackets and leveling assemblies provided on the leveling brackets, the lifting assemblies and the leveling assemblies are fixedly connected to the frame, the drive assemblies are configured for driving wheels to rotate and the lifting assemblies are configured for lifting the leveling brackets.

Abstract: An accurate grid locking method for a target composite tracking system in a terminal area comprises a cooperative engagement processer in each platform which performs for arranging a radar data storage structure, storing the target plot data received by the cooperative engagement processer in the corresponding radar data storage structure one by one, processing target plot data of a previous sector to form a target track, distributing the obtained target track to another platform on a data link, and receiving track data of a remote target distributed by another platform, inputting the track data into the plot data storage structure of the platform.

Abstract: The disclosure herein provides a device, a method and a computer-readable storage medium for quantitative phase imaging, and relates to the field of quantitative phase imaging. The specific implementation scheme is: Obtain a multiplexed interferogram of the sample, where the multiplexed interferogram is a sample beam composed of at least two beams with different wavelengths to illuminate the sample and penetrate into the cube beam splitter Combine at least two beams with different wavelengths as the reference beam, and the combined beam is the imaging image sampled by the camera; and perform phase retrieval on the multiplexed interference image to obtain each beam of the sample in the composite sample beam The phase map at the wavelength of Using the embodiments of the disclosure herein, one imaging acquisition and one phase retrieval are to acquire the phase maps of at least two wavelength channels.

Abstract: A green body is provided. The green body is made of a superhard material, is used for being fixed on a matrix so as to be machined into a cutting edge part of a cutter. The green body includes a first side surface and a second side surface. Both the first side surface and the second side surface twist at a set helical angle. After being fixed to the matrix, the green body is machined into an edge part for cutting, such as a main cutting edge and a center cutting edge located on the green body made of a same superhard material. The green body is applied to machining the cutting edge of the cutter. A rotating center has a continuous and intact center cutting edge formed by a superhard material.

Abstract: A TOF depth measuring device includes: an emission module projects a dot matrix pattern onto a target object, and an acquisition module includes an image sensor configured to receive reflected optical signals reflected by the target object. First pixels in the pixel array detect reflected optical signals of real light spots reflected by the target object, and second pixels in the pixel array detect reflected optical signals of real light spots reflected more than once. The TOF depth measuring device further includes a processor, connected to the emission module and the acquisition module, filters the first reflected optical signal to obtain a third reflected optical signal, and calculate a phase difference based on the third reflected optical signal to obtain a first depth map of the target object.

Abstract: A method is provided and includes acquiring a digital slide comprising objects of at least two sizes, the objects including a first object of a first size and a second object of a second size different from the first size, for each of the first object and the second object, acquiring images of a corresponding object in at least two scales based on the digital slide, where the acquired images of the corresponding object in the at least two scales include an image of a larger scale and an image of a smaller scale, the image of the larger scale having a smaller image size and a higher image resolution than the image of the smaller scale, and determining, from the images of the corresponding object in the at least two scales, an image having an image size that corresponds to a size of the corresponding object.

Abstract: The present invention discloses an oil-contained wastewater treatment apparatus applying the integrative physical methods. The wastewater treatment system of the invention may include a main tank, where the upper part is a rectangular body and the lower part is designed to a multi-bucket bottom structure. Two oil collection boxes are arranged to both outside ends of tank. A mud discharging outlet is attached to the bottom of the tank. Meanwhile, both of a water outlet and an electric polarizer are localized at the end face of the effluent on the tank. A power supply for the electro-adsorber is fixed to the inlet end on the top face of the tank. Divided by upper and lower deflectors, the inside of the tank is divided to three processing units, i.e., sludge-water separation unit, degradation-coalescence treatment unit, and sedimentation-electric polarization unit. Vortex centripetal gas flotation is applied to remove oil. Electro-adsorption induces the micelle clustering to achieve the decolorization.