Patents by Inventor Rui-wen Shi

Rui-wen Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6004943
    Abstract: This invention is directed to an article, such as a medical device, for local delivery of genes. The article comprises a substrate coated with a cross-linked protein. The invention is also directed to a method for coating an article with cross-linked protein. An additive may be optionally incorporated into the coating. The crosslinked protein coating can strongly absorb genes. Thus, the coated article can be used to locally deliver genes to a target site. The coating of the invention exhibits excellent biocompatibility and biodegradability, and does not cause toxicity or side-effects.
    Type: Grant
    Filed: November 26, 1996
    Date of Patent: December 21, 1999
    Assignees: Inst. of Biomedical Engineering, Chinese Acdmy of Med. Science, Cardiovascular Inst. of Fu Wai Hospital, Chinese Acdmy of Med. Science
    Inventors: Rui-wen Shi, Run-lin Gao