Abstract: A continuous process for preparing exo-THDCPD by isomerization of endo-THDCPD includes the step of passing endo-THDCPD and hydrogen gas successively through a first reaction zone filled with a hydrogenation protectant and a second reaction zone filled with an isomerization catalyst to perform a hydroisomerization reaction so as to obtain exo-THDCPD, wherein the hydrogenation protectant is a supported metal hydrogenation catalyst, and the isomerization catalyst is a metal-modified molecular sieve catalyst. The process converts endo-THDCPD to exo-THDCPD, with a conversion of greater than 86% and a target product selectivity of greater than 94%.

Abstract: Disclosed are a printed circuit board, a display module and a driving method thereof, and a display device. The printed circuit board includes a blank area and an encapsulation area. The printed circuit board includes a first metal layer including a first metal pattern and a second metal pattern separated from each other, a first pad connected to the first metal pattern, and a second pad connected to the second metal pattern. The first metal pattern is located in the blank area, and the second metal pattern is located in the encapsulation area. The first pad and the second pad are configured to be connected to an electrostatic isolation device, and the second metal pattern is configured to be connected to a functional electronic device.

Abstract: Provided are anti-CLDN18 (in particular, anti-CLDN18.2) antibodies or antigen-binding fragments thereof, isolated polynucleotides encoding the same, pharmaceutical composition comprising the same and the uses thereof.

Abstract: The present invention relates to a long chain alkyl esteramine lipid compound as shown in Formula I, preparation method therefor as well as use thereof in nucleic acid delivery, the long chain alkyl esteramine lipid compound provided by the present invention has an excellent encapsulation rate and delivery effect as a lipid molecule in delivering disease treatment or preventive agents, showing lower toxicity and certain tissue distribution characteristics, and providing a basis of more selections for delivering disease therapeutic or prophylactic agents.

Abstract: The present invention relates to methods, kits, and compositions for detecting and/or diagnosing metastatic potential of cancer cells or for evaluating prognosis in a patient with cancer by detection of the protein expression level of an HLA class I molecule and/or the copy number variation of a polynucleotide encoding the HLA class I molecule. The present invention also relates to the use of the protein expression level of an HLA class I molecule and/or the copy number variation of a polynucleotide encoding the HLA class I molecule as a prognosis biomarker and metastasis predictive biomarker of cancer.

Abstract: The present application provides a use of a nitric oxide releasing agent in preparing a medicament, wherein the medicament is used for preventing or treating EGFR inhibition associated epithelial diseases in a subject. The present application further provides a pharmaceutical composition or a kit comprising EGFR inhibitor and nitric oxide releasing agent.

Abstract: The present application provides a use of a nitric oxide releasing agent in preparing a medicament, wherein the medicament is used for preventing or treating EGFR inhibition associated epithelial diseases in a subject. The present application further provides a pharmaceutical composition or a kit comprising EGFR inhibitor and nitric oxide releasing agent.

Abstract: A spout for a connection between a bus bar and a circuit breaker in switchgear includes a housing and a fixed contact. The housing is formed of insulative material and includes a tubular body having an inner cavity and a radial first ventilation opening, a base portion having a first longitudinal opening, and a fixed contact receiving portion having a second longitudinal opening. The fixed contact is formed of a conductive material, has an outer contact surface exposed through the second longitudinal opening, and forms a portion of an outer surface of the spout. A switchgear includes a wall dividing a circuit breaker compartment from a bus bar compartment, and the base portion of the spout is securable to the wall.

Abstract: The present invention relates to methods, kits, and compositions for detecting and/or diagnosing metastatic potential of cancer cells or for evaluating prognosis in a patient with cancer by detection of the protein expression level of an HLA class I molecule and/or the copy number variation of a polynucleotide encoding the HLA class I molecule. The present invention also relates to the use of the protein expression level of an HLA class I molecule and/or the copy number variation of a polynucleotide encoding the HLA class I molecule as a prognosis biomarker and metastasis predictive biomarker of cancer.

Abstract: The present invention relates to methods, kits, and compositions for detecting and/or diagnosing metastatic potential of cancer cells or for evaluating prognosis in a patient with cancer by detection of the protein expression level of an HLA class I molecule and/or the copy number variation of a polynucleotide encoding the HLA class I molecule. The present invention also relates to the use of the protein expression level of an HLA class I molecule and/or the copy number variation of a polynucleotide encoding the HLA class I molecule as a prognosis biomarker and metastasis predictive biomarker of cancer.

Abstract: An embedded pole is provided. The embedded pole includes an insulation shell, a conductive circuit, wherein at least a portion of the conductive circuit is housed within the insulation shell, and a ventilation system including an external heat sink coupled to the conductive circuit and external to the insulation shell, and an internal heat sink coupled to the conductive circuit and positioned within the insulation shell.

Abstract: A spout for a connection between a bus bar and a circuit breaker in switchgear includes a housing and a fixed contact. The housing is formed of insulative material and includes a tubular body having an inner cavity and a radial first ventilation opening, a base portion having a first longitudinal opening, and a fixed contact receiving portion having a second longitudinal opening. The fixed contact is formed of a conductive material, has an outer contact surface exposed through the second longitudinal opening, and forms a portion of an outer surface of the spout. A switchgear includes a wall dividing a circuit breaker compartment from a bus bar compartment, and the base portion of the spout is securable to the wall.

Abstract: A spout for a connection between a bus bar and a circuit breaker in switchgear includes a housing and a fixed contact. The housing is formed of insulative material and includes a tubular body having an inner cavity and a radial first ventilation opening, a base portion having a first longitudinal opening, and a fixed contact receiving portion having a second longitudinal opening. The fixed contact is formed of a conductive material, has an outer contact surface exposed through the second longitudinal opening, and forms a portion of an outer surface of the spout. A switchgear includes a wall dividing a circuit breaker compartment from a bus bar compartment, and the base portion of the spout is securable to the wall. A method of increasing heat dissipation within switchgear using the spout includes securing a bus bar to the outer contact surface, and dissipating heat through the radial ventilation opening.

Abstract: The present invention relates to methods, kits, and compositions for detecting and/or diagnosing metastatic potential of cancer cells or for evaluating prognosis in a patient with cancer by detection of the protein expression level of an HLA class I molecule and/or the copy number variation of a polynucleotide encoding the HLA class I molecule. The present invention also relates to the use of the protein expression level of an HLA class I molecule and/or the copy number variation of a polynucleotide encoding the HLA class I molecule as a prognosis biomarker and metastasis predictive biomarker of cancer.

Abstract: A spout for a connection between a bus bar and a circuit breaker in switchgear includes a housing and a fixed contact. The housing is formed of insulative material and includes a tubular body having an inner cavity and a radial first ventilation opening, a base portion having a first longitudinal opening, and a fixed contact receiving portion having a second longitudinal opening. The fixed contact is formed of a conductive material, has an outer contact surface exposed through the second longitudinal opening, and forms a portion of an outer surface of the spout. A switchgear includes a wall dividing a circuit breaker compartment from a bus bar compartment, and the base portion of the spout is securable to the wall. A method of increasing heat dissipation within switchgear using the spout includes securing a bus bar to the outer contact surface, and dissipating heat through the radial ventilation opening.