Abstract: Microfluidic gradient generators that can create robust platforms that can not only be used for creating co-cultures of cells with various ratios, but also can simultaneously generate gradients of mechanical and chemical stresses. A chip utilizes microchambers embedded within channels to provide space for 3D cell culture and exposes these cells to gradients of mechanical shear stress and a chemical treatment.

Abstract: A method of measuring a stress-strain curve in a cell-cell adhesion interface, the method including: providing a structure including a first movable island supported by a first beam, a second movable island supported by a second beam, and a gap therebetween connected by a pair of cells forming a junction, the pair of cells comprising a cell-cell adhesion interface having an initial length defined by a distance between nuclei of the pair of cells; moving the second movable island with a defined displacement; determining a displacement of the first movable island based on moving the second movable island; calculating a difference between the displacement of the first movable island and the defined displacement of the second movable island based on moving the second movable island; determining an applied strain in the cell-cell adhesion interface between the pair of cells based on the difference divided by the initial length of the cell-cell adhesion interface; calculating a force between the cell-cell adhesion

Abstract: A method of measuring a stress-strain curve in a sample, the method including: providing a structure including a first movable island supported by a first beam, a second movable island supported by a second beam, and a gap therebetween connected by a sample, the sample including an initial length; moving the second movable island with a defined displacement; determining a displacement of the first movable island based on moving the second movable island; calculating a difference between the displacement of the first movable island and the defined displacement of the second movable island based on moving the second movable island; determining an applied strain in the sample based on the difference divided by the initial length of the sample; calculating a force on the sample based on the displacement of the first movable island; calculating a stress on the sample based on the force; and determining the stress-strain curve of the sample by plotting the calculated stress against the applied strain.

Abstract: Electroporation devices and methods of making the same. An electroporation device includes a plurality of independently controllable or addressable electrode pairs, a plurality of reaction chambers, each reaction chamber including a first chamber, a second chamber and a porous substrate separating the first chamber from the second chamber, and each reaction chambers being disposed between one of the plurality of independently controllable or addressable electrode pairs, a plurality of first microfluidic channels configured to deliver a cargo solution from a cargo inlet port to the plurality of first chambers, and a plurality of second microfluidic channels configured to deliver a cell culture from a cell inlet port to the plurality of second chambers. In operation, application of a voltage to an electrode pair permeabilizes the membranes of the cells adhered to the porous substrate in the reaction chamber disposed between the electrode pair.

Abstract: The invention provides a method for preparing an ordered cell-containing microarray, and a system for preparing an ordered cell-containing microarray.

Abstract: A method of measuring a stress-strain curve in a cell-cell adhesion interface, the method including: providing a structure including a first movable island supported by a first beam, a second movable island supported by a second beam, and a gap therebetween connected by a pair of cells forming a junction, the pair of cells comprising a cell-cell adhesion interface having an initial length defined by a distance between nuclei of the pair of cells; moving the second movable island with a defined displacement; determining a displacement of the first movable island based on moving the second movable island; calculating a difference between the displacement of the first movable island and the defined displacement of the second movable island based on moving the second movable island; determining an applied strain in the cell-cell adhesion interface between the pair of cells based on the difference divided by the initial length of the cell-cell adhesion interface; calculating a force between the cell-cell adhesion

Abstract: Microfluidic gradient generators that can create robust platforms that can not only be used for creating co-cultures of cells with various ratios, but also can simultaneously generate gradients of mechanical and chemical stresses. A chip utilizes microchambers embedded within channels to provide space for 3D cell culture and exposes these cells to gradients of mechanical shear stress and a chemical treatment.

Abstract: Disclosed in embodiments of the present invention are a control method, apparatus, device, and medium for a power factor correction (PFC) circuit, used for solving the problems of high implementation costs and relatively severe THD that exist in existing PFC circuit control methods. The control method for a power factor correction (PFC) circuit, comprising: acquiring circuit parameter information of the PFC circuit; when determining that the circuit parameter information meets a preset switching condition, switching a control mode of the PFC circuit to be a continuous conduction mode (CCM).

Abstract: Disclosed in the present invention are a control method and device for a power factor correction circuit. The method comprises: obtaining voltage information of the power factor correction circuit; determining whether the voltage information meets a set switching condition; if the set switching condition is met, switching a control mode of the power factor correction circuit to a continuous conduction mode; and if the set switching condition is not met, switching the control mode of the power factor correction circuit to a triangular wave current mode or a critical conduction mode. Compared with the prior art, the control mode of the power factor correction circuit can be different according to the voltage information in the embodiment of the present invention, instead of remaining unchanged at all times, without increasing the withstand voltage level of the bus capacitor, thereby reducing the cost of implementation.

Abstract: Disclosed in embodiments of the present invention are a control method, apparatus, device, and medium for a power factor correction (PFC) circuit, used for solving the problems of high implementation costs and relatively severe THD that exist in existing PFC circuit control methods. The control method for a power factor correction (PFC) circuit, comprising: acquiring circuit parameter information of the PFC circuit; when determining that the circuit parameter information meets a preset switching condition, switching a control mode of the PFC circuit to be a continuous conduction mode (CCM).

Abstract: In general overview, the present disclosure is directed to a system and method for selectively displaying a frame of an application user interface on a mobile computing device. A user interface analyzer on a mobile computing device analyzes a user interface for an application executing on a remote server. The user interface analyzer identifies frames in the user interface, the positions of the frames, relationships between frames, and horizontal and vertical panning offsets to move between adjacent frames. The mobile computing device receives a user input requesting the display of an adjacent frame. Based on the information the user interface analyzer obtained, the mobile computing device displays an adjacent frame of the user interface.

Abstract: In general overview, the present disclosure is directed to a system and method for selectively displaying a frame of an application user interface on a mobile computing device. A user interface analyzer on a mobile computing device analyzes a user interface for an application executing on a remote server. The user interface analyzer identifies frames in the user interface, the positions of the frames, relationships between frames, and horizontal and vertical panning offsets to move between adjacent frames. The mobile computing device receives a user input requesting the display of an adjacent frame. Based on the information the user interface analyzer obtained, the mobile computing device displays an adjacent frame of the user interface.

Abstract: In general overview, the present disclosure is directed to a system and method for selectively displaying a frame of an application user interface on a mobile computing device. A user interface analyzer on a mobile computing device analyzes a user interface for an application executing on a remote server. The user interface analyzer identifies frames in the user interface, the positions of the frames, relationships between frames, and horizontal and vertical panning offsets to move between adjacent frames. The mobile computing device receives a user input requesting the display of an adjacent frame. Based on the information the user interface analyzer obtained, the mobile computing device displays an adjacent frame of the user interface.

Abstract: In general overview, the present disclosure is directed to a system and method for selectively displaying a frame of an application user interface on a mobile computing device. A user interface analyzer on a mobile computing device analyzes a user interface for an application executing on a remote server. The user interface analyzer identifies frames in the user interface, the positions of the frames, relationships between frames, and horizontal and vertical panning offsets to move between adjacent frames. The mobile computing device receives a user input requesting the display of an adjacent frame. Based on the information the user interface analyzer obtained, the mobile computing device displays an adjacent frame of the user interface.

Abstract: The performance of distributed systems can be improved when a server remotely controls off-screen surfaces at a client coupled to the server via a communications network. The server instructs the client to form an off-screen surface exhibiting a number of particular attributes. The client selects and allocates a particular memory region and forms the off-screen surface therein, as instructed by the server. The server subsequently provides the client with an indicia of graphical data and instructs the client to locate the graphical data and to copy the data into the off-screen surface. In response to an error condition, the server transmits a duplicate of the off-screen surface to the client with instructions to update the client's on-screen surface using this duplicate surface.

Abstract: The performance of distributed systems can be improved by reducing the amount of graphical line data transmitted between a server and a client. The server separates the graphical line data into a plurality of strips. The server then determines a quantized angle and a strip length for each of the strips. The beginning coordinate of the graphical line data is packaged together with the quantized angle or indicia of the quantized angle and the strip length data into a protocol packet and compressed prior to transmission to the client. In one embodiment the strip data transmitted to the client includes a second indicia that a particular strip has been previously transmitted to the client and the client is instructed to form the strip using locally stored data.

Abstract: The performance of distributed systems can be improved by reducing the amount of graphical line data transmitted between a server and a client. The server separates the graphical line data into a plurality of strips. The server then determines a quantized angle and a strip length for each of the strips. The beginning coordinate of the graphical line data is packaged together with the quantized angle or indicia of the quantized angle and the strip length data into a protocol packet and compressed prior to transmission to the client. In one embodiment the strip data transmitted to the client includes a second indicia that a particular strip has been previously transmitted to the client and the client is instructed to form the strip using locally stored data.

Abstract: The performance of distributed systems can be improved when a server remotely controls off-screen surfaces at a client coupled to the server via a communications network. The server instructs the client to form an off-screen surface exhibiting a number of particular attributes. The client selects and allocates a particular memory region and forms the off-screen surface therein, as instructed by the server. The server subsequently provides the client with an indicia of graphical data and instructs the client to locate the graphical data and to copy the data into the off-screen surface. In response to an error condition, the server transmits a duplicate of the off-screen surface to the client with instructions to update the client's on-screen surface using this duplicate surface.