Patents by Inventor Ruixuan Jia

Ruixuan Jia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF CYP4V2 AND RDCVF IN THE MANUFACTURE OF MEDICAMENT
    Publication number: 20240024433
    Abstract: The present application relates to the use of CYP4V2 and RdCVF in the manufacture of a medicament for treating, alleviating, and/or preventing a disease or disorder associated with retinal pigment epithelium (RPE) atrophy. The present application also relates to an isolated nucleic acid molecule comprising a polynucleotide encoding CYP4V2 and a polynucleotide encoding RdCVF. The present application also relates to an amino acid sequence encoded by the isolated nucleic acid molecule, a vector comprising the isolated nucleic acid molecule, and a cell comprising the nucleic acid or the vector as well as use thereof in the manufacture of a medicament for treating, alleviating, and/or preventing a disease or disorder associated with retinal pigment epithelium (RPE) atrophy.
    Type: Application
    Filed: July 27, 2023
    Publication date: January 25, 2024
    Inventors: Liping Yang, Shaohong Chen, Ruixuan Jia, Fan Zhang, Qiaoli Zeng, Saichao He, Tianyong Shi, Dandan Hao, Shangwei Jiang, Hongjie Pei, Luying Zeng
  • VECTOR AND METHOD FOR TREATING BIETTI'S CRYSTALLINE DYSTROPHY
    Publication number: 20240018541
    Abstract: A vector includes a polynucleotide encoding CYP4V2 and a promoter operably linked to the polynucleotide encoding CYP4V2. The vector has a good expression effect, high expression speed, and more stable expression intensity. Cells, pharmaceutical compositions, and kits can include the vector. Methods for treating, alleviating, and/or preventing a disease or disorder associated with retinal pigment epithelium (RPE) atrophy can include administering the vector to a subject.
    Type: Application
    Filed: July 13, 2022
    Publication date: January 18, 2024
    Inventors: Liping Yang, Shaohong Chen, Ruixuan Jia, Tianfu Zhang, Fan Zhang, Saichao He, Tianyong Shi, Dandan Hao, Hongjie Pei, Luying Zeng
  • USE OF CYP4V2 AND RDCVF IN THE MANUFACTURE OF MEDICAMENT
    Publication number: 20230146121
    Abstract: The present application relates to the use of CYP4V2 and RdCVF in the manufacture of a medicament for treating, alleviating, and/or preventing a disease or disorder associated with retinal pigment epithelium (RPE) atrophy. The present application also relates to an isolated nucleic acid molecule comprising a polynucleotide encoding CYP4V2 and a polynucleotide encoding RdCVF. The present application also relates to an amino acid sequence encoded by the isolated nucleic acid molecule, a vector comprising the isolated nucleic acid molecule, and a cell comprising the nucleic acid or the vector as well as use thereof in the manufacture of a medicament for treating, alleviating, and/or preventing a disease or disorder associated with retinal pigment epithelium (RPE) atrophy.
    Type: Application
    Filed: July 16, 2020
    Publication date: May 11, 2023
    Inventors: Liping Yang, Shaohong Chen, Ruixuan Jia, Tianfu Zhang, Fan Zhang, Qiaoli Zeng, Saichao He, Tianyong Shi, Dandan Hao, Shangwei Jiang, Hongjie PEI, Xudong Wang, Luying Zeng