Patents by Inventor Rujian Ma

Rujian Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200157108
    Abstract: The present invention relates to PDE9 inhibitors, their synthesis, and their use for treatment of benign prostate hyperplasia, beta thalassemia, and sickle cell disease.
    Type: Application
    Filed: May 25, 2018
    Publication date: May 21, 2020
    Inventors: Niels SVENSTRUP, Jun ZHANG, Jikui SUN, Yuyin CHEN, Jianshe KONG, Rujian MA, Junhua ZHANG, Liang QIN, Huanming XIAO, Jinxu SUN, Xiao MENG, Fenglai SUN, Jingyang ZHU
  • Publication number: 20090036708
    Abstract: The present invention provides a process for the preparation of a nonracemic a-amino acid derivative from an optically active N-acyl lactam using an organometallic reagent to effect the opening of the ring followed by reduction of the ketone carbonyl to an alcohol or a methylene, or by a reductive amination to an amine, or by a ketalization reaction.
    Type: Application
    Filed: October 14, 2004
    Publication date: February 5, 2009
    Inventors: Lanqi Jia, Rujian Ma, Feng Zhang, Yifeng Shi, Jingchao Dong, Ge Li