Patents by Inventor Rulin Wang

Rulin Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BCG based vaccine compositions and methods of use thereof
    Patent number: 12661393
    Abstract: The present disclosure relates to a BCG based therapeutic agent using a BCG strain that overexpresses the STING agonist, c-di-AMP. This BCG strain, called BCG-disA-OE, enhances the elevated trained immunity of macrophages and promotes early anti-viral Type I interferon responses in a subject, providing protection against viral infections such as primary respiratory infections and SARS-CoV-2 infection.
    Type: Grant
    Filed: October 1, 2021
    Date of Patent: June 23, 2026
    Assignee: The Johns Hopkins University
    Inventors: Alok Singh, Peter Um, Keira Cohen, William Bishai, Rulin Wang, Srinivasan Yegnasubramanian, Trinity J. Bivalacqua