Patents by Inventor Rulin Zhang

Rulin Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diagnostic methods for congestive heart failure
    Patent number: 8263351
    Abstract: The invention provides an assay for the quantification of circulating glycophorin in biological fluid samples. The circulating glycophorin measured by this assay is a truncated glycophorin diagnostic for congestive heart failure (CHF).
    Type: Grant
    Filed: February 10, 2011
    Date of Patent: September 11, 2012
    Assignee: Nexus DX, Inc.
    Inventors: George Jackowski, Tracy Van Lieshout, Brad Thatcher, Rulin Zhang, Jason Yantha, Michele Rasamoelisolo
  • DIAGNOSTIC METHODS FOR CONGESTIVE HEART FAILURE
    Publication number: 20110183436
    Abstract: The invention provides an assay for the quantification of circulating glycophorin in biological fluid samples. The circulating glycophorin measured by this assay is a truncated glycophorin diagnostic for congestive heart failure (CHF).
    Type: Application
    Filed: February 10, 2011
    Publication date: July 28, 2011
    Applicant: NEXUS DX, Inc.
    Inventors: George Jackowski, Tracy Van Lieshout, Brad Thatcher, Rulin Zhang, Jason Yantha, Michele Rasamoelisolo
  • Diagnostic methods for congestive heart failure
    Publication number: 20090068676
    Abstract: The invention provides an assay for the quantification of circulating glycophorin in biological fluid samples. The circulating glycophorin measured by this assay is a truncated glycophorin diagnostic for congestive heart failure (CHF).
    Type: Application
    Filed: April 13, 2007
    Publication date: March 12, 2009
    Inventors: George Jackowski, Tracy Van Lieshout, Brad Thatcher, Rulin Zhang, Jason Yantha, Michele Rasamoelisolo
  • Diagnostic methods for congestive heart failure
    Publication number: 20050100964
    Abstract: The invention provides an assay for the quantification of circulating glycophorin in biological fluid samples. The circulating glycophorin measured by this assay is a truncated glycophorin diagnostic for congestive heart failure (CHF).
    Type: Application
    Filed: November 11, 2003
    Publication date: May 12, 2005
    Inventors: George Jackowski, Tracy Van Lieshout, Brad Thatcher, Rulin Zhang, Jason Yantha, Michele Rasamoelisolo
  • Amino acid sequence pattern matching
    Patent number: 6891154
    Abstract: A method for locating pattern matches in amino acids by use of various and sequential filters capable of determining inner sample pattern matches, inner group pattern matches, and word matching for purposes of further analysis or data mining. Filters include the use of a scoring scheme, comparison of scan numbers versus sequence of common ions to be MS/MS, and daughter ion subtraction for obtaining pattern match candidates.
    Type: Grant
    Filed: August 30, 2002
    Date of Patent: May 10, 2005
    Assignee: Syn X Pharma, Inc.
    Inventors: Weimin Zhu, John Marshall, Christopher Smith, Rulin Zhang
  • Method for identification of glycosylated polypeptides
    Publication number: 20040253659
    Abstract: The instant invention provides a stepwise method for identification of glycosylated polypeptides. The steps of the method involve treatment of a biological sample containing a glycosylated polypeptide with at least one protease to begin peptide digestion, followed by deglycosylation and subsequent re-digestion with at least one protease to result in deglycosylated polypeptide fragments. The deglycosylated polypeptide fragments are then sequenced using mass spectrometry and identified by sequence comparison with a database of known sequences.
    Type: Application
    Filed: June 11, 2003
    Publication date: December 16, 2004
    Inventors: Michele Rasamoelisolo, Rulin Zhang, George Jackowski
  • Amino acid sequence pattern matching
    Publication number: 20040041089
    Abstract: A method for locating pattern matches in amino acids by use of various and sequential filters capable of determining inner sample pattern matches, inner group pattern matches, and word matching for purposes of further analysis or data mining. Filters include the use of a scoring scheme, comparison of scan numbers versus sequence of common ions to be MS/MS, and daughter ion subtraction for obtaining pattern match candidates.
    Type: Application
    Filed: August 30, 2002
    Publication date: March 4, 2004
    Inventors: Weimin Zhu, John Marshall, Christopher Smith, Rulin Zhang
  • Diagnosis and treatment of dementia utilizing thrombospondin
    Publication number: 20030119074
    Abstract: A method for diagnosing various forms of dementia, including MCI, and Alzheimer's disease(AD) is disclosed. The method involves directly detecting the presence of a biochemical marker, specifically thrombospondin, in bodily fluid, preferably blood or a blood product. The detection is by an immunoassay incorporating an antibody specific to thrombospondin, or alternatively an autoantibody to a thrombospondin antibody.
    Type: Application
    Filed: December 20, 2001
    Publication date: June 26, 2003
    Inventors: George Jackowski, Rulin Zhang