Patents by Inventor Rumiko Abe

Rumiko Abe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for an anthracycline derivative, and an anthracyclinone derivative useful for the process
    Patent number: 4564674
    Abstract: A process for producing an anthracycline derivative represented by the general formula: ##STR1## where R.sup.1 is an acyl group, each of X.sup.1 and X.sup.2 is a hydrogen atom, a methoxy group, a hydroxyl group, a halogen atom or a lower alkyl group, each of Y.sup.1 and Y.sup.2 is a hydrogen atom, an alkoxy group or a hydroxyl group, and Z is a hydrogen atom or a protected hydroxyl group, which comprises reacting an anthracyclinone derivative represented by the general formula: ##STR2## where R is a hydrogen atom or a trialkylsilyl group, and X.sup.1, X.sup.2, Y.sup.1, Y.sup.2 and Z are as defined above, with a 1-acyl-sugar derivative represented by the general formula: ##STR3## where R.sup.2 is an acyl group and R.sup.1 is as defined above, in the presence of a silyl sulfonic acid derivative represented by the general formula:R.sup.5 R.sup.4 R.sup.3 SiOSO.sub.2 A (IV)where each of R.sup.3, R.sup.4 and R.sup.
    Type: Grant
    Filed: October 19, 1984
    Date of Patent: January 14, 1986
    Assignee: Sagami Chemical Research Center
    Inventors: Shiro Terashima, Yoshikazu Kimura, Michiyo Suzuki, Teruyo Matsumoto, Rumiko Abe