Patents by Inventor Rumulo J. C. Albuquerque

Rumulo J. C. Albuquerque has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • sVEGFR-2 and its role in lymphangiogenesis modulation
    Patent number: 8846386
    Abstract: Disclosed herein are nucleic acid molecules comprising a nucleotide sequence of sVEGF-2, proteins encoded by those sequences and antibodies that bind to the protein. Also disclosed are methods for inhibiting or enhancing expression or activity of sVEGFR-2 and methods for inhibiting graft rejection, particularly cornea graph rejection. Also described are methods for inhibiting lymphangiogenesis and lymphatic endothelial cell proliferation by administering an effective amount of sVEGFR-2 and methods for treating lymphedema by inhibiting the activity of sVEGFR-2.
    Type: Grant
    Filed: December 18, 2008
    Date of Patent: September 30, 2014
    Assignee: University of Kentucky Research Foundation
    Inventors: Jayakrishna Ambati, Rumulo J. C. Albuquerque