Patents by Inventor Run-Pan Du

Run-Pan Du has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chimeric immunogens
    Patent number: 7671186
    Abstract: Multimeric hybrid genes encoding the corresponding chimeric protein comprise a gene sequence coding for an antigenic region of a protein from a first pathogen linked to a gene sequence coding for an antigenic region of a protein from a second pathogen. The pathogens particularly are parainfluenza virus (PIV) and respiratory syncytial virus (RSV). A single recombinant immunogen is capable of protecting infants and similar susceptible individuals against diseases caused by both PIV and RSV.
    Type: Grant
    Filed: June 13, 2007
    Date of Patent: March 2, 2010
    Assignee: Sanofi Pasteur Limited
    Inventors: Michel H. Klein, Run-Pan Du, Mary E. Ewasyshyn
  • Chimeric immunogens
    Patent number: 7619063
    Abstract: Multimeric hybrid genes encoding the corresponding chimeric protein comprise a gene sequence coding for an antigenic region of a protein from a first pathogen linked to a gene sequence coding for an antigenic region of a protein from a second pathogen. The pathogens particularly are parainfluenza virus (PIV) and respiratory syncytial virus (RSV). A single recombinant immunogen is capable of protecting infants and similar susceptible individuals against diseases caused by both PIV and RSV.
    Type: Grant
    Filed: June 13, 2007
    Date of Patent: November 17, 2009
    Assignee: Sanofi Pasteur Limited
    Inventors: Michel H. Klein, Run-Pan Du, Mary E. Ewasyshyn
  • Chimeric immunogens
    Patent number: 7514535
    Abstract: Multimeric hybrid genes encoding the corresponding chimeric protein comprise a gene sequence coding for an antigenic region of a protein from a first pathogen linked to a gene sequence coding for an antigenic region of a protein from a second pathogen. The pathogens particularly are parainfluenza virus (PIV) and respiratory syncytial virus (RSV). A single recombinant immunogen is capable of protecting infants and similar susceptible individuals against diseases caused by both PIV and RSV.
    Type: Grant
    Filed: June 13, 2007
    Date of Patent: April 7, 2009
    Assignee: Sanofi Pasteur Limited
    Inventors: Michel H. Klein, Run-Pan Du, Mary E. Ewasyshyn
  • Chimeric immunogens
    Patent number: 7498153
    Abstract: Multimeric hybrid genes encoding the corresponding chimeric protein comprise a gene sequence coding for an antigenic region of a protein from a first pathogen linked to a gene sequence coding for an antigenic region of a protein from a second pathogen. The pathogens particularly are parainfluenza virus (PIV) and respiratory syncytial virus (RSV). A single recombinant immunogen is capable of protecting infants and similar susceptible individuals against diseases caused by both PIV and RSV.
    Type: Grant
    Filed: June 13, 2007
    Date of Patent: March 3, 2009
    Assignee: Sanofi Pasteur Limited
    Inventors: Michel H. Klein, Run-Pan Du, Mary E. Ewasyshyn
  • Chimeric immunogens
    Publication number: 20080311624
    Abstract: Multimeric hybrid genes encoding the corresponding chimeric protein comprise a gene sequence coding for an antigenic region of a protein from a first pathogen linked to a gene sequence coding for an antigenic region of a protein from a second pathogen. The pathogens particularly are parainfluenza virus (PIV) and respiratory syncytial virus (RSV). A single recombinant immunogen is capable of protecting infants and similar susceptible individuals against diseases caused by both PIV and RSV.
    Type: Application
    Filed: June 13, 2007
    Publication date: December 18, 2008
    Inventors: Michel H. Klein, Run-Pan Du, Mary E. Ewasyshyn
  • Chimeric immunogens
    Publication number: 20080312412
    Abstract: Multimeric hybrid genes encoding the corresponding chimeric protein comprise a gene sequence coding for an antigenic region of a protein from a first pathogen linked to a gene sequence coding for an antigenic region of a protein from a second pathogen. The pathogens particularly are parainfluenza virus (PIV) and respiratory syncytial virus (RSV). A single recombinant immunogen is capable of protecting infants and similar susceptible individuals against diseases caused by both PIV and RSV.
    Type: Application
    Filed: June 13, 2007
    Publication date: December 18, 2008
    Inventors: Michel H. Klein, Run-Pan Du, Mary E. Ewasyshyn
  • Chimeric immunogens
    Patent number: 7405273
    Abstract: Multimeric hybrid genes encoding the corresponding chimeric protein comprise a gene sequence coding for an antigenic region of a protein from a first pathogen linked to a gene sequence coding for an antigenic region of a protein from a second pathogen. The pathogens particularly are parainfluenza virus (PIV) and respiratory syncytial virus (RSV). A single recombinant immunogen is capable of protecting infants and similar susceptible individuals against diseases caused by both PIV and RSV.
    Type: Grant
    Filed: June 13, 2007
    Date of Patent: July 29, 2008
    Assignee: Sanofi Pasteur Limited
    Inventors: Michel H. Klein, Run-Pan Du, Mary E. Ewasyshyn
  • Chimeric immunogens
    Publication number: 20080032342
    Abstract: Multimeric hybrid genes encoding the corresponding chimeric protein comprise a gene sequence coding for an antigenic region of a protein from a first pathogen linked to a gene sequence coding for an antigenic region of a protein from a second pathogen. The pathogens particularly are parainfluenza virus (PIV) and respiratory syncytial virus (RSV). A single recombinant immunogen is capable of protecting infants and similar susceptible individuals against diseases caused by both PIV and RSV.
    Type: Application
    Filed: June 13, 2007
    Publication date: February 7, 2008
    Inventors: Michel Klein, Run-Pan Du, Mary Ewasyshyn
  • Chimeric immunogens
    Publication number: 20080027213
    Abstract: Multimeric hybrid genes encoding the corresponding chimeric protein comprise a gene sequence coding for an antigenic region of a protein from a first pathogen linked to a gene sequence coding for an antigenic region of a protein from a second pathogen. The pathogens particularly are parainfluenza virus (PIV) and respiratory syncytial virus (RSV). A single recombinant immunogen is capable of protecting infants and similar susceptible individuals against diseases caused by both PIV and RSV.
    Type: Application
    Filed: June 13, 2007
    Publication date: January 31, 2008
    Inventors: Michel Klein, Run-Pan Du, Mary Ewasyshyn
  • Chimeric immunogens
    Publication number: 20080015340
    Abstract: Multimeric hybrid genes encoding the corresponding chimeric protein comprise a gene sequence coding for an antigenic region of a protein from a first pathogen linked to a gene sequence coding for an antigenic region of a protein from a second pathogen. The pathogens particularly are parainfluenza virus (PIV) and respiratory syncytial virus (RSV). A single recombinant immunogen is capable of protecting infants and similar susceptible individuals against diseases caused by both PIV and RSV.
    Type: Application
    Filed: June 13, 2007
    Publication date: January 17, 2008
    Inventors: Michel Klein, Run-Pan Du, Mary Ewasyshyn
  • Chimeric immunogens
    Patent number: 7244589
    Abstract: Multimeric hybrid genes encoding the corresponding chimeric protein comprise a gene sequence coding for an antigenic region of a protein from a first pathogen linked to a gene sequence coding for an antigenic region of a protein from a second pathogen. The pathogens particularly are parainfluenza virus (PIV) and respiratory syncytial virus (RSV). A single recombinant immunogen is capable of protecting infants and similar susceptible individuals against diseases caused by both PIV and RSV.
    Type: Grant
    Filed: May 10, 2004
    Date of Patent: July 17, 2007
    Assignee: Sanifo Pasteur Limited
    Inventors: Michel Henri Klein, Run-Pan Du, Mary Elizabeth Ewasyshyn
  • Transferrin receptor genes of
    Patent number: 7241449
    Abstract: Purified and isolated nucleic acid molecules are provided which encode Tbp2 proteins of M. catarrhalis strains M35, 3 and LES1. The nucleic acid sequence may be used to produce recombinant Tbp2 proteins of the strain of Moraxella free of other proteins of the Moraxella strain for purposes of diagnostics and medical treatment. Furthermore, the nucleic acid molecules may be used in the diagnosis of infection.
    Type: Grant
    Filed: April 12, 1999
    Date of Patent: July 10, 2007
    Assignee: Aventis Pasteur Limited
    Inventors: Lisa E. Myers, Anthony B. Schryvers, Robin E. Harkness, Sheena M. Loosmore, Run-Pan Du, Yan-Ping Yang, Michel H. Klein
  • Chimeric immunogens
    Publication number: 20050136067
    Abstract: Multimeric hybrid genes encoding the corresponding chimeric protein comprise a gene sequence coding for an antigenic region of a protein from a first pathogen linked to a gene sequence coding for an antigenic region of a protein from a second pathogen. The pathogens particularly are parainfluenza virus (PIV) and respiratory syncytial virus (RSV). A single recombinant immunogen is capable of protecting infants and similar susceptible individuals against diseases caused by both PIV and RSV.
    Type: Application
    Filed: May 10, 2004
    Publication date: June 23, 2005
    Inventors: Michel Klein, Run-Pan Du, Mary Ewasyshyn
  • Transferrin receptor genes of Moraxella
    Patent number: 6440701
    Abstract: Purified and isolated nucleic acid molecules are provided which encode transferrin receptor proteins of Moraxella, such as M. catarrhalis or a fragment or an analog of the transferrin receptor protein. The nucleic acid sequence may be used to produce recombinant transferrin receptor proteins Tbp1 and Tbp2 of the strain of Moraxella free of other proteins of the Moraxella strain for purposes of diagnostics and medical treatment. Furthermore, the nucleic acid molecule may be used in the diagnosis of infection.
    Type: Grant
    Filed: April 14, 1998
    Date of Patent: August 27, 2002
    Assignee: Aventis Pasteur Limited
    Inventors: Lisa E. Myers, Anthony B. Schryvers, Robin E. Harkness, Sheena M. Loosmore, Run-Pan Du, Yan-Ping Yang, Michel H. Klein
  • Transferrin receptor of moraxella
    Patent number: 6437096
    Abstract: Purified and isolated nucleic acid molecules are provided which encode transferrin receptor proteins of Moraxella, such as M. catarrhalis or a fragment or an analog of the transferrin receptor protein. The nucleic acid sequence may be used to produce recombinant transferrin receptor proteins Tbp1 and Tbp2 of the strain of Moraxella free of other proteins of the Moraxella strain for purposes of diagnostics and medical treatment. Furthermore, the nucleic acid molecule may be used in the diagnosis of infection.
    Type: Grant
    Filed: January 3, 1997
    Date of Patent: August 20, 2002
    Assignee: Aventis Pasteur Limited
    Inventors: Lisa E. Myers, Anthony B. Schryvers, Robin E. Harkness, Sheena M. Loosmore, Run-Pan Du, Yan-Ping Yang, Michel H. Klein
  • Multimeric hybrid gene encoding a chimeric protein which confers protection against parainfluenza virus and respiratory synctial virus
    Patent number: 6225091
    Abstract: Multimeric hybrid genes encoding the corresponding chimeric protein comprise a gene sequence coding for an antigenic region of a protein from a first pathogen linked to a gene sequence coding for an antigenic region of a protein from a second pathogen. The pathogens particularly are parainfluenza virus (PIV) and respiratory syncytial virus (RSV). A single recombinant immunogen is capable of protecting infants and similar susceptible individuals against diseases caused by both PIV and RSV.
    Type: Grant
    Filed: January 6, 1993
    Date of Patent: May 1, 2001
    Assignee: Connaught Laboratories Limited
    Inventors: Michel H. Klein, Run-Pan Du, Mary E. Ewasyshyn
  • Lactoferrin receptor genes of Moraxella
    Patent number: 6184371
    Abstract: Purified and isolated nucleic acid molecules are provided which encode lactoferrin receptor proteins of Moraxella, such as M. catarrhalis, or a fragment or an analog of the lactoferrin receptor protein. The nucleic acid sequence may be used to produce recombinant lactoferrin receptor proteins Lbp1, Lbp2 and ORF3 of the strain of Moraxella free of other proteins of the Moraxella strain for purposes of diagnostics and medical treatment. Furthermore, the nucleic acid molecule may be used in the diagnosis of infection.
    Type: Grant
    Filed: May 8, 1998
    Date of Patent: February 6, 2001
    Assignee: Connaught Laboratories Limited
    Inventors: Sheena M. Loosmore, Run-Pan Du, Quijun Wang, Yan-Ping Yang, Michel H. Klein
  • Infection detection method using chimeric protein
    Patent number: 6171783
    Abstract: Multimeric hybrid genes encoding the corresponding chimeric protein comprise a gene sequence coding for an antigenic region of a protein from a first pathogen linked to a gene sequence coding for an antigenic region of a protein from a second pathogen. The pathogens particularly are parainfluenza virus (PIV) and respiratory syncytial virus (RSV). A single recombinant immunogen is capable of protecting infants and similar susceptible individuals against diseases caused by both PIV and RSV.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: January 9, 2001
    Assignee: Connaught Laboratories Limited
    Inventors: Michel H. Klein, Run-Pan Du, Mary E. Ewasyshyn
  • Chimeric immunogens
    Patent number: 6168786
    Abstract: Multimeric hybrid genes encoding the corresponding chimeric protein comprise a gene sequence coding for an antigenic region of a protein from a first pathogen linked to a gene sequence coding for an antigenic region of a protein from a second pathogen. The pathogens particularly are parainfluenza virus (PIV) and respiratory syncytial virus (RSV). A single recombinant immunogen is capable of protecting infants and similar susceptible individuals against diseases caused by both PIV and RSV.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: January 2, 2001
    Assignee: Connaught Laboratories Limited
    Inventors: Michel H. Klein, Run-Pan Du, Mary E. Ewasyshyn
  • DNA encoding a transferrin receptor of Moraxella
    Patent number: 6090576
    Abstract: Purified and isolated nucleic acid molecules are provided which encode transferrin receptor proteins of Moraxella, such as M. catarrhalis or a fragment or an analog of the transferrin receptor protein. The nucleic acid sequence may be used to produce recombinant transferrin receptor proteins Tbp1 and Tbp2 of the strain of Moraxella free of other proteins of the Moraxella strain for purposes of diagnostics and medical treatment. Furthermore, the nucleic acid molecule may be used in the diagnosis of infection.
    Type: Grant
    Filed: March 8, 1996
    Date of Patent: July 18, 2000
    Assignee: Connaught Laboratories Limited
    Inventors: Lisa E. Myers, Anthony B. Schryvers, Robin E. Harkness, Sheena M. Loosmore, Run-Pan Du, Yan-Ping Yang, Michel H. Klein