Abstract: The invention relates to a method for analyzing potential ablation therapies (1), in particular for patients (P) with atrial fibrillation, via a control system (2), wherein the method comprises an analysis step (3) in which the control system (2) applies a trained machine learning model (4) to input data (5) thereby generating output data (6), wherein the input data (5) comprise electrical biomarkers (7) derived from ECG data (8) from a patient (P) of at least one potential ablation therapy (1), the potential ablation therapy (1) including at least one potential ablation event (9) with a potential ablation location (10), wherein the output data (6) comprise a predicted change of the electrical biomarkers (7) after applying the potential ablation therapy (1) to the patient (P), wherein the predicted change is derived from the input data (5) via the trained machine learning model (4).

Abstract: A medical device includes a heating element and at least one multifunctional wire coupled to the heating element. The multifunctional wire provides current for both heating the heating element and for determining the temperature of the medical device as a thermocouple. The heating element is further coupled to one or more additional wires for completing both a heating circuit and a thermocouple circuit in combination with the multifunctional wire. In one form, the multifunctional wire and a thermocouple return wire is coupled to a first end of the heating element and heating return wire is coupled to a second end of the heating element. In another form, a first multifunctional wire is coupled to the first end of the heating element, and a second multifunctional wire is coupled to the second end of the heating element.

Abstract: The present disclosure provides for a device and methods of use to endoluminally ablate and/or occlude a body vessel using a current to perform resistive heating. The device includes a resistive coil having thermistor properties where the resistance of the coil changes as a function of temperature. A control unit will detect the voltage, current, and resistance in the coil during the heating of the coil to determine the temperature of the coil. As occlusion occurs and the cooling effect of blood flow decreases, less power will be required to maintain the coil at a desired temperature. Detecting a large decrease in required power will indicate to the control unit that the body vessel has become occluded.

Abstract: The present disclosure provides for a device and methods of use to endoluminally ablate and/or occlude a body vessel using a radiofrequency (“RF”) signal and a current to perform resistive heating. The device may have a RF mode and a resistive mode, and may perform each mode in sequential order until the vessel is fully occluded. The device further comprises a control unit to operate the device in its various modes.

Abstract: The present disclosure provides for a device and methods of use to endoluminally ablate and/or occlude a body vessel using a radiofrequency (“RF”) signal and a current to perform resistive heating. The device may have a RF mode and a resistive mode, and may perform each mode in sequential order until the vessel is fully occluded. The device further comprises a control unit to operate the device in its various modes. The device may be provided in a system including an occlusive element, such as a balloon catheter, to prevent blood flow through the ablation/occlusion site.

Abstract: The present disclosure provides for a device and methods of use to endoluminally ablate and/or occlude a body vessel using a radiofrequency (“RF”) signal and a current to perform resistive heating. The device may have a RF mode and a resistive mode, and may perform each mode in sequential order until the vessel is fully occluded. The device further comprises a control unit to operate the device in its various modes.

Abstract: The present disclosure provides for a device and methods of use to endoluminally ablate and/or occlude a body vessel using a radiofrequency (“RF”) signal and a current to perform resistive heating. The device may have a RF mode and a resistive mode, and may perform each mode in sequential order until the vessel is fully occluded. The device further comprises a control unit to operate the device in its various modes. The device may be provided with a dielectric coating to create a low-friction tip or coil.

Abstract: A system for controlling deployment of an implantable medical includes an implantable medical device and a gripper mechanism. One or both of the medical device and the gripper mechanism are made from a shape-memory alloy material having a temperature at which the material will transition from a martensite state to an austenite state. The shape-memory alloy material has a transition temperature that is higher than a normal body temperature and a wide hysteresis band, with a temperature at which the material transitions back into the martensite state being below a normal body temperature. The medical device will expand or change shape upon being heated by a current passing therethrough, but will not transition into its remembered shape until such current is applied.

Abstract: RF ablation apparatus includes an anode electrode assembly including an anode terminal housed within a catheter. The catheter includes a distal end wall which is disposed in a plane substantially perpendicular to the longitudinal dimension of the catheter. The anode electrode is slidably received within the cathode and can be extended out beyond the distal end of the catheter to provide at least a first terminal for an ablation circuit. The distal end wall is sized and shaped to hold a thrombus formed on the anode electrode so that the anode electrode can be withdrawn from within the thrombus formation and into the catheter, without the thrombus formation being pulled with the anode terminal. The outer surface of the catheter, or at least at the distal end thereof, is made of an insulating or non-conducting material, such that a thrombus does not form over the catheter.