Patents by Inventor Runze Yang

Runze Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treating developmental dysplasis of hip
    Patent number: 12636277
    Abstract: Embodiments of the present disclosure provide a method for treating developmental dysplasia of the hip. The method includes administering a therapeutically effective amount of a pharmaceutical composition to a subject suffering from the developmental dysplasia of the hip. The pharmaceutical composition includes a substance capable of inhibiting expression of Midkine (MDK), and the substance capable of inhibiting the expression of MDK is Midkine inhibitor (IMDK).
    Type: Grant
    Filed: May 13, 2025
    Date of Patent: May 26, 2026
    Assignee: WEST CHINA HOSPITAL OF SICHUAN UNIVERSITY
    Inventors: Weili Fu, Runze Yang, Yunan Hu, Xin Ma, Huiling Liu, Minghao Ge, Jian Li
  • METHODS FOR TREATING DEVELOPMENTAL DYSPLASIS OF HIP
    Publication number: 20250375425
    Abstract: Embodiments of the present disclosure provide a method for treating developmental dysplasia of the hip. The method includes administering a therapeutically effective amount of a pharmaceutical composition to a subject suffering from the developmental dysplasia of the hip. The pharmaceutical composition includes a substance capable of inhibiting expression of Midkine (MDK), and the substance capable of inhibiting the expression of MDK is Midkine inhibitor (IMDK).
    Type: Application
    Filed: May 13, 2025
    Publication date: December 11, 2025
    Applicant: WEST CHINA HOSPITAL OF SICHUAN UNIVERSITY
    Inventors: Weili FU, Runze YANG, Yunan HU, Xin MA, Huiling LIU, Minghao GE, Jian LI
  • LEONURINE NANOCOMPOSITE HYDROGEL AND PREPARATION METHODS AND APPLICATIONS THEREOF
    Publication number: 20250186387
    Abstract: The present disclosure relates to a field of biomedical technology. Embodiments of the present disclosure provide a leonurine nanocomposite hydrogel and preparation method and application thereof, including: dissolving dopamine (DA) monomers and inducing oxidation and self-polymerization of the DA to obtain polydopamine (PDA) nanoparticles, grafting thiol polyethylene glycol folic acid (SH-PEG-FA) on a surface of the PDA nanoparticles to obtain folic acid polydopamine (FA-PDA) nanocarriers; loading a leonurine (Leon) using the FA-PDA nanocarriers of the step 1 to obtain FA-PDA@Leon; encapsulating the FA-PDA@Leon of the step 2 into a gel matrix to obtain gel@FA-PDA@Leon hydrogel.
    Type: Application
    Filed: December 11, 2024
    Publication date: June 12, 2025
    Applicant: WEST CHINA HOSPITAL OF SICHUAN UNIVERSITY
    Inventors: Weili FU, Runze YANG, Liwei YAN, Jian LI
  • Leonurine nanocomposite hydrogel and preparation methods and applications thereof
    Patent number: 12324798
    Abstract: The present disclosure relates to a field of biomedical technology. Embodiments of the present disclosure provide a leonurine nanocomposite hydrogel and preparation method and application thereof, including: dissolving dopamine (DA) monomers and inducing oxidation and self-polymerization of the DA to obtain polydopamine (PDA) nanoparticles, grafting thiol polyethylene glycol folic acid (SH-PEG-FA) on a surface of the PDA nanoparticles to obtain folic acid polydopamine (FA-PDA) nanocarriers; loading a leonurine (Leon) using the FA-PDA nanocarriers of the step 1 to obtain FA-PDA@Leon; encapsulating the FA-PDA@Leon of the step 2 into a gel matrix to obtain gel@FA-PDA@Leon hydrogel.
    Type: Grant
    Filed: December 11, 2024
    Date of Patent: June 10, 2025
    Assignee: WEST CHINA HOSPITAL OF SICHUAN UNIVERSITY
    Inventors: Weili Fu, Runze Yang, Liwei Yan, Jian Li