Abstract: A system, method, and computer program product that allows the additive manufacturing of a component from a build material held within a tank, such as the manufacture of a hydrogel biomemetic structure. The tank includes a window with a light source positioned adjacent the window. A build platform is within the tank and opposite the light source and an actuator is coupled to the build platform that movie the build platform within the tank and relative to the window. A computing device is operably coupled to the actuator and controls the operation of the actuator to build a component by positioning the build platform within the tank at predetermined distances from the window with the build platform at least partially submerged in any build material contained in the tank, and moving the build platform relative to the window and the light source thereby building a component.

Abstract: A system and method for conditioning a tissue are provided. The system includes a substrate, a plurality of microwells formed in the substrate, and a microsphere associated with each of the plurality of microwells. The system also includes a pair of flexible pillars within each of the plurality of microwells. Each flexible pillar includes a first end bonded to a respective microwell and at least one flexible pillar has a second end bonded to the microsphere. The flexible pillars are configured to deflect when exposed to a magnetic field to controllably stretch microtissue spanning the flexible pillars.

Abstract: A system and method for conditioning a tissue are provided. The system includes a substrate, a plurality of microwells formed in the substrate, and a microsphere associated with each of the plurality of microwells. The system also includes a pair of flexible pillars within each of the plurality of microwells. Each flexible pillar includes a first end bonded to a respective microwell and at least one flexible pillar has a second end bonded to the microsphere. The flexible pillars are configured to deflect when exposed to a magnetic field to controllably stretch microtissue spanning the flexible pillars.