Patents by Inventor Ruojing Yang

Ruojing Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR SCREENING DRUG-SACCHARIDE CONJUGATES
    Publication number: 20170254798
    Abstract: Methods for identifying drug-saccharide conjugates that bind the mannose receptor, C type 1, (MRC1) and may be taken up by cells expressing MRC1, and the use of such drug-saccharide conjugates for treatment of particular diseases are described. In particular, the methods for identifying insulin-saccharide conjugates that bind the MRC1 receptor and may be taken up by cells expressing the MRC1 and use of such conjugates for treatment of diabetes are described.
    Type: Application
    Filed: March 4, 2016
    Publication date: September 7, 2017
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Yingjun Mu, Ruojing Yang, Xinghai Li, Margaret Wu, Qing Dallas-yang, Yuli Chen, Ge Dai, Songnian Lin, David E. Kelley, Mark Erion
  • METHOD FOR SCREENING DRUG-SACCHARIDE CONJUGATES
    Publication number: 20170248580
    Abstract: Methods for identifying drug-saccharide conjugates that bind the mannose receptor, C type 1, (MRC1) and may be taken up by cells expressing MRC1, and the use of such drug-saccharide conjugates for treatment of particular diseases are described. In particular, the methods for identifying insulin-saccharide conjugates that bind the MRC1 receptor and may be taken up by cells expressing the MRC1 and use of such conjugates for treatment of diabetes are described.
    Type: Application
    Filed: May 15, 2017
    Publication date: August 31, 2017
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Yingjun Mu, Ruojing Yang, Xinghai Li, Margaret Wu, Qing Dallas-yang, Yuli Chen, Ge Dai, Songnian Lin, David E. Kelley, Mark Erion
  • Methods and compositions for modulating glycogen synthesis and breakdown
    Publication number: 20040180845
    Abstract: The invention provides reagents and methods for reducing hyperglycemia and caloric intake in a subject in need thereof. Also provided are screening methods for identifying compounds that reduce hyperglycemia and/or caloric intake. Further provides are screening methods for identifying compounds that enhance glycogen synthesis without substantially impairing responsiveness to glycogenolytic signals.
    Type: Application
    Filed: March 13, 2003
    Publication date: September 16, 2004
    Inventors: Christopher B. Newgard, Ruojing Yang