Abstract: The present invention provides potent antibiofilm and antifouling compounds albofungin and derivatives thereof isolated from Streptomyces chrestomyceticus BCC 24770, the construction of high-yield strains for albofungin production, and application of albofungin-based copolymer coatings to object or surfaces, particularly to inhibit fouling by marine organisms using hydrolysable and degradable antifouling coatings incorporated with albofungins.

Abstract: The subject invention pertains to compositions and methods of eradicating biofilms and/or inhibiting the formation of a biofilms or fouling by non-biofilm forming organisms using elasnin-based compositions. In certain embodiments, the elasnin can be combined with antimicrobial compounds and/or traditional coating ingredients.