Abstract: A preparation method and an application method of a multifunctional intelligent cellulose-based visual label are provided. The multifunctional intelligent cellulose-based visual label solved a problem that an existing freshness indicator film is narrowed in an indication range. The preparation method includes the following steps: step 1 of carboxylation modification; step 2 of cationic grafting; step 3 of preparation of a composite dye solution; step 4 of preparation of responsive fibers; and step 5 of performing vacuum filtration to prepare paper, thereby obtaining the multifunctional intelligent cellulose-based visual label. The food freshness is indicated with the obtained intelligent visual label. An indicated pH value range is 4-8, color variation can be completed within 30 seconds, and the food freshness can be accurately indicated. The multifunctional intelligent cellulose-based visual label is low-carbon, efficient, green, safe, and wide in the indication range, and can be used in food monitoring.