Patents by Inventor Ruoyu Zhang
Ruoyu Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250133686Abstract: A system and method for providing a short-term power bridging architecture, particularly tailored to improvements in electrochemical cell packs that include an aggregation of electrochemical cells having at least one electrode using a TMCCC. A rack architecture for a power bridging rack, includes a power path; and a low voltage path; wherein elements disposed in the power path include protection elements and provide a protection function; wherein the low voltage path is divided into a control section and an interface section; wherein the control section provides a balance function; and wherein the interface section interfaces to one or more devices.Type: ApplicationFiled: May 22, 2024Publication date: April 24, 2025Applicant: Natron Energy, Inc.Inventors: Gopalakrishnan Parakulam, Stevan Polak, Ruoyu Zhang
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Patent number: 12157916Abstract: The present disclosure provides methods of identifying unreliable biological samples that may be mislabeled or contaminated, by determining the heteroplasmy and homoplasmy of mitochondrial DNA present in the biological samples.Type: GrantFiled: August 6, 2021Date of Patent: December 3, 2024Assignee: Regeneron Pharmaceuticals, Inc.Inventors: Ruoyu Zhang, Wei Keat Lim, Gurinder Atwal
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Patent number: 11978190Abstract: A rapid detection system for water and impurity of machine-harvested seed cotton in purchase link, including: a seed cotton large-impurity-cleaning device, a seed cotton sample case, a driving and transmission device, a cotton pressing device, an image collection and processing device, and a moisture regain rate detection device and a control cabinet. The seed cotton sample case consists of a positioning plate and a high light transmittance glass case, the weighing device consists of a weighing sensor, a pallet, and an electric push rod. The driving and transmission device consists of the rollers, the motor of conveyor belts and conveyor belts, the cotton pressing device consists of an electric push rod, a connecting rod, a connecting plate, and a high light transmittance glass plate. Said rapid detection system could realize the rapid detection to the impurity rate and moisture regain rate of the seed cotton.Type: GrantFiled: August 24, 2021Date of Patent: May 7, 2024Assignee: Shihezi UniversityInventors: Ruoyu Zhang, Long Wan, Yinglan Jiang, Mengyun Zhang, Jinqiang Chang, Fangdan Song
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Publication number: 20240043987Abstract: The invention discloses a method for preparing a ruthenium rotary sputtering target, including the following steps: S100: manually press molding: putting ruthenium powder into a mold, and manually pressurizing the ruthenium powder to form the ruthenium powder into a relative density is a first preformed target with a first preset density; S200: vacuum hot pressing, placing the first stage target together with the mold into a vacuum hot press for processing to obtain a second preformed target with a relative density of the second preset density The preformed target material, and the second preset density is bigger than the first preset density; S300: hot isostatic pressing, the second preformed target material is put into the hot isostatic pressing for processing, and the relative density of the third preformed target is obtained. Assuming the density of the forming target, the third preset density is bigger than the second preset density, and the third preset density is exceeded 99.5%.Type: ApplicationFiled: September 2, 2022Publication date: February 8, 2024Applicant: Singapore Advanced Thin Film Material Private LimitedInventors: Shuangming Zheng, Xiangyu Bai, Ruoyu Zhang, Yanbin Xia, Kok Tong Phang, Yusheng Wu
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Patent number: 11821637Abstract: An energy-saving system using electric heat pump to recover flue gas waste heat for district heating uses flue gas waste heat recovery tower to absorb the sensible and latent heat in the high-temperature flue gas by direct contact heat and mass transfer. The circulating water is sprayed from the top and the flue gas flows upwards in the tower. The electric heat pump is indirectly connected with circulating water through the anti-corrosion and high-efficiency water-water plate heat exchanger. The return water of the heat-supply network enters the electric heat pump through the anti-corrosion and high-efficiency water-water plate heat exchanger and exchanges heat indirectly with the high-temperature circulating water. The electric heat pump uses the electric energy of the power plant as the driving power.Type: GrantFiled: March 25, 2019Date of Patent: November 21, 2023Assignee: DALIAN UNIVERSITY OF TECHNOLOGYInventors: Haichao Wang, Xiaozhou Wu, Ruoyu Zhang, Lin Duanmu, Xiangli Li
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Publication number: 20220403470Abstract: The present disclosure is directed to probe sets for sequencing a mitochondrial genomic DNA, methods of sequencing a mitochondrial DNA using the probe sets, and methods of designing probe sets for sequencing a mitochondrial genomic DNA.Type: ApplicationFiled: September 16, 2020Publication date: December 22, 2022Applicant: CORNELL UNIVERSITYInventors: Zhenglong GU, Xiaoxian GUO, Yiqin WANG, Ruoyu ZHANG
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Publication number: 20220170113Abstract: Provided herein is a method for distinguishing an aberrant methylation level for DNA from a first cell type, including steps of (a) providing a test data set that includes (i) methylation states for a plurality of sites from test genomic DNA from at least one test organism, and (ii) coverage at each of the sites for detection of the methylation states; (b) providing methylation states for the plurality of sites in reference genomic DNA from one or more reference individual organisms, (c) determining, for each of the sites, the methylation difference between the test genomic DNA and the reference genomic DNA, thereby providing a normalized methylation difference for each site; and (d) weighting the normalized methylation difference for each site by the coverage at each of the sites, thereby determining an aggregate coverage-weighted normalized methylation difference score.Type: ApplicationFiled: February 7, 2022Publication date: June 2, 2022Applicant: Illumina, Inc.Inventors: Jonathan Toung, Li Liu, Min-Jui Shen, Ruoyu Zhang
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Patent number: 11319593Abstract: Provided herein is a method for distinguishing an aberrant methylation level for DNA from a first cell type, including steps of (a) providing a test data set that includes (i) methylation states for a plurality of sites from test genomic DNA from at least one test organism, and (ii) coverage at each of the sites for detection of the methylation states; (b) providing methylation states for the plurality of sites in reference genomic DNA from one or more reference individual organisms, (c) determining, for each of the sites, the methylation difference between the test genomic DNA and the reference genomic DNA, thereby providing a normalized methylation difference for each site; and (d) weighting the normalized methylation difference for each site by the coverage at each of the sites, thereby determining an aggregate coverage-weighted normalized methylation difference score.Type: GrantFiled: December 15, 2016Date of Patent: May 3, 2022Assignee: Illumina, Inc.Inventors: Jonathan Toung, Li Liu, Min-Jui Richard Shen, Ruoyu Zhang
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Publication number: 20220067912Abstract: Disclosed is a rapid detection system for water and impurity of machine-harvested seed cotton in purchase link, including: a seed cotton large-impurity-cleaning device, a seed cotton sample case, a driving and transmission device, a cotton pressing device, an image collection and processing device, a moisture regain rate detection device and a control cabinet; the seed cotton sample case consists of a positioning plate and a high light transmittance glass case, the weighing device consists of a weighing sensor, a pallet, and an electric push rod; the driving and transmission device consists of the rollers, the motor of conveyor belts and conveyor belts, the cotton pressing device consists of an electric push rod, a connecting rod, a connecting plate, and a high light transmittance glass plate. Said rapid detection system could realize the rapid detection to the impurity rate and moisture regain rate of the seed cotton.Type: ApplicationFiled: August 24, 2021Publication date: March 3, 2022Inventors: Ruoyu ZHANG, Long WAN, Yinglan JIANG, Mengyun ZHANG, Jinqiang CHANG, Fangdan SONG
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Publication number: 20220042091Abstract: The present disclosure provides methods of identifying unreliable biological samples that may be mislabeled or contaminated, by determining the heteroplasmy and homoplasmy of mitochondrial DNA present in the biological samples.Type: ApplicationFiled: August 6, 2021Publication date: February 10, 2022Inventors: Ruoyu Zhang, Wei Keat Lim, Gurinder Atwal
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Publication number: 20210239326Abstract: An energy-saving system using electric heat pump to recover flue gas waste heat for district heating uses flue gas waste heat recovery tower to absorb the sensible and latent heat in the high-temperature flue gas by direct contact heat and mass transfer. The circulating water is sprayed from the top and the flue gas flows upwards in the tower. The electric heat pump is indirectly connected with circulating water through the anti-corrosion and high-efficiency water-water plate heat exchanger. The return water of the heat-supply network enters the electric heat pump through the anti-corrosion and high-efficiency water-water plate heat exchanger and exchanges heat indirectly with the high-temperature circulating water. The electric heat pump uses the electric energy of the power plant as the driving power.Type: ApplicationFiled: March 25, 2019Publication date: August 5, 2021Inventors: Haichao WANG, Xiaozhou WU, Ruoyu ZHANG, Lin DUANMU, Xiangli LI
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Publication number: 20210090686Abstract: Method to process single cell gene expression data to reveal gene-gene correlations by applying a noise regularization process to reduce the gene-gene correlation artifacts. The computer-implemented method of the present application comprises processing gene expression data for normalization or imputation, applying a noise regularization process to the normalized or imputed gene expression data, and applying gene-gene correlation calculation process to obtain correlated gene pairs. Random noises based on an expression value of a gene in a cell in an expression matrix are added to obtain a noise regularized expression matrix.Type: ApplicationFiled: September 25, 2020Publication date: March 25, 2021Inventors: Gurinder Singh Atwal, Wei Keat Lim, Ruoyu Zhang
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Publication number: 20190073691Abstract: A method for enabling a content sponsor to design a cost-effective content campaign. The content sponsor initiates a content campaign. The content sponsor is presented with a set of proposed channels on which to display the content and either accepts the proposed channels or selects an alternative set of channels. If an alternative set of channels is chosen, the content sponsor is presented with an alert comprising data predicting the result of presenting the content on the alternative set of channels. If the content sponsor does not heed the alert, the content sponsor is presented with an option to implement a split test, which involves implementing multiple content campaigns using different sets of channels. Finally, a result report is presented to the content sponsor. In some embodiments, the result report comprises a counterfactual report comparing the results of two or more campaigns implemented using different sets of channels.Type: ApplicationFiled: September 1, 2017Publication date: March 7, 2019Inventors: Ori Hanegby, Max K. Comer, Chinmay Deepak Karande, Ruoyu Zhang, Joshua Elliot Geller, Jie Xu, Nuwan Senaratna
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Publication number: 20190005523Abstract: An online system receives a content item and budget for presenting the content item from a publishing user, and estimates certain interactions by users presented with the content item if the budget is increased. The online system applies one or more models to the received budget to estimate one or more interactions with the content item for different increased budgets. The online system presents the estimated interactions and different increased budgets to the publishing user. To encourage the publishing user to increase the budget, the online system may present estimated interactions by users corresponding to different increased budgets when the publishing user provides the content item to the online system. The online system may limit presentation of estimated interactions for increased budgets to increased budgets for which the online system estimated interactions with at least a threshold accuracy and may identify an increased budget optimizing a number of estimated interactions.Type: ApplicationFiled: June 28, 2017Publication date: January 3, 2019Inventors: Ori Hanegby, Ruoyu Zhang, Cheran Wu, Jie Xu, Daozheng Chen, Joshua Elliot Geller, Vighnesh Avadhani, Zhen Yao
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Publication number: 20170175205Abstract: Provided herein is a method for distinguishing an aberrant methylation level for DNA from a first cell type, including steps of (a) providing a test data set that includes (i) methylation states for a plurality of sites from test genomic DNA from at least one test organism, and (ii) coverage at each of the sites for detection of the methylation states; (b) providing methylation states for the plurality of sites in reference genomic DNA from one or more reference individual organisms, (c) determining, for each of the sites, the methylation difference between the test genomic DNA and the reference genomic DNA, thereby providing a normalized methylation difference for each site; and (d) weighting the normalized methylation difference for each site by the coverage at each of the sites, thereby determining an aggregate coverage-weighted normalized methylation difference score.Type: ApplicationFiled: December 15, 2016Publication date: June 22, 2017Applicant: Illumina, Inc.Inventors: Jonathan Toung, Li Liu, Min-Jui Richard Shen, Ruoyu Zhang