Patents by Inventor Rupa S. Shetty

Rupa S. Shetty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aminopyrazine compounds
    Patent number: 8962623
    Abstract: A compound of formula (I): wherein all symbols have the same meanings as defined in the specification; a salt thereof, a solvate thereof, an N-oxide thereof, or a prodrug thereof, has an Itk inhibitory activity, and is useful as a method for preventing and/or treating atopic dermatitis, and the like.
    Type: Grant
    Filed: February 29, 2012
    Date of Patent: February 24, 2015
    Assignee: Locus Pharmaceuticals, Inc.
    Inventors: Rupa S. Shetty, Martha J. Kelly, Bin Liu, Jinming Zou, Kristofer K. Moffett, Younghee Lee, Dora Do-York Wong
  • AMINOPYRAZINE COMPOUNDS
    Publication number: 20140187529
    Abstract: A compound of formula (I): wherein all symbols have the same meanings as defined in the specification; a salt thereof, a solvate thereof, an N-oxide thereof, or a prodrug thereof, has an Itk inhibitory activity, and is useful as a method for preventing and/or treating atopic dermatitis, and the like.
    Type: Application
    Filed: February 29, 2012
    Publication date: July 3, 2014
    Applicant: LOCUS PHARMACEUTICALS, INC.
    Inventors: Rupa S. Shetty, Martha J. Kelly, Bin Liu, Jinming Zou, Kristopher K. Moffett, Younghee Lee
  • Urea inhibitors of MAP kinases
    Patent number: 7741479
    Abstract: The present invention is directed to a compound having the formula wherein R1, R2, G, and Q are defined herein. The compounds of the present invention are useful as inhibitors of protein kinases such as MAP kinases, in particular p38 kinases. The present invention is also directed to compositions comprising a compound according to the above formula. The compounds and compositions described herein are useful for treating and preventing an inflammatory condition or disease. The present invention is also directed to a method of treating or preventing a protein kinase-mediated condition.
    Type: Grant
    Filed: December 7, 2005
    Date of Patent: June 22, 2010
    Assignee: Locus Pharmaceuticals, Inc.
    Inventors: Enrique Luis Michelotti, Eric Bruce Springman, Duyan Nguyen, Rupa S. Shetty, Younghee Lee, Kristofer Kent Moffett, Jennifer Lee Ludington, Ted Tsutomis Fujimoto, Zenon D. Konteatis, Bin Liu, Frank Hollinger, Bruce D. Dorsey
  • 17?-amino and hydroxylamino-11 ?-arylsteroids and their derivatives having agonist or antagonist hormonal properties
    Patent number: 7018991
    Abstract: The invention is directed to a novel class of steroids which exhibit potent antiprogestational activity.
    Type: Grant
    Filed: July 2, 2003
    Date of Patent: March 28, 2006
    Assignee: Research Triangle Institute
    Inventors: C. Edgar Cook, John A. Kepler, Gary S. Bartley, Rupa S. Shetty
  • 17 Beta-amino and hydroxylamino-11 beta-arylsteroids and their derivatives having agonist or antagonist hormonal properties
    Publication number: 20040023936
    Abstract: The invention is directed to a novel class of steroids which exhibit potent antiprogestational activity.
    Type: Application
    Filed: July 2, 2003
    Publication date: February 5, 2004
    Applicant: RESEARCHTRIANGLE INSTITUTE
    Inventors: C. Edgar Cook, John A. Kepler, Gary S. Bartley, Rupa S. Shetty
  • 17&bgr;-amino and hydroxylamino-11&bgr;-arylsteroids and their derivatives having agonist or antagonist hormonal properties
    Patent number: 6620801
    Abstract: The invention is directed to a novel class of steroids which exhibit potent antiprogestational activity.
    Type: Grant
    Filed: July 2, 2001
    Date of Patent: September 16, 2003
    Assignee: Research Triangle Institute
    Inventors: C. Edgar Cook, John A. Kepler, Gary S. Bartley, Rupa S. Shetty
  • 17beta-amino and hydroxylamino-11beta-arylsteroids and their derivatives having agonist or antagonist hormonal properties
    Publication number: 20020065257
    Abstract: The invention is directed to a novel class of steroids which exhibit potent antiprogestational activity.
    Type: Application
    Filed: July 2, 2001
    Publication date: May 30, 2002
    Applicant: RESEARCH TRIANGLE INSTITUTE
    Inventors: C. Edgar Cook, John A. Kepler, Gary S. Bartley, Rupa S. Shetty
  • 17.beta.-nitro-11.beta.-arylsteroids and their derivatives having agonist or antagonist hormonal properties
    Patent number: 6093707
    Abstract: The invention is directed to a novel class of steroids which exhibit potent antiprogestational activity.
    Type: Grant
    Filed: November 5, 1999
    Date of Patent: July 25, 2000
    Assignee: Research Triangle Institute
    Inventors: C. Edgar Cook, John A. Kepler, Rupa S. Shetty, Gary S. Bartley, David Yue-wei Lee
  • 11.beta.-aryl-17, 17-spirothiolane-substituted steroids
    Patent number: 6043235
    Abstract: The invention is directed to 11.beta.-aryl-17,17-spirothiolane substituted steroid compounds of formula (I) exhibiting binding to the progestin receptor. ##STR1## Also disclosed are methods of using and process of making the compounds.
    Type: Grant
    Filed: July 21, 1999
    Date of Patent: March 28, 2000
    Assignee: Research Triangle Institute
    Inventors: C. Edgar Cook, Rupa S. Shetty, John A. Kepler, David Y.-W. Lee
  • 17.beta.-nitro-11.beta.-arylisteroids and their derivatives having agonist or antagonist hormonal properties
    Patent number: 6015805
    Abstract: The invention is directed to 11.beta.-arylsteroids of formula II: ##STR1## wherein R.sup.1, R.sup.6, R.sup.8, R.sup.12 and X are as defined by the specification. The compounds exhibit potent antiprogestational activity and are useful in the treatment of fibroids, endometriosis, cervical ripening prior to delivery, hormone replacement therapy and in the control of fertility.
    Type: Grant
    Filed: May 25, 1999
    Date of Patent: January 18, 2000
    Assignee: Research Triangle Research North Carolina
    Inventors: C. Edgar Cook, John A. Kepler, Rupa S. Shetty, Gary S. Bartley, David Yue-wei Lee
  • 17.beta.-nitro-11.beta.-arylsteroids and their derivatives having agonist or antagonist hormonal properties
    Patent number: 5962444
    Abstract: The invention is directed to 17.beta.-nitro-11.beta.-arylsteroids of formula I: ##STR1## wherein R.sup.1, R.sup.6, R.sup.7, R.sup.12 and X are as defined by the specification. The compounds exhibit potent antiprogestational activity and are useful in the treatment of fibroids, endometriosis, cervical ripening prior to delivery, hormone replacement therapy and in the control of fertility.
    Type: Grant
    Filed: May 29, 1998
    Date of Patent: October 5, 1999
    Assignee: Research Triangle Institute
    Inventors: C. Edgar Cook, John A. Kepler, Rupa S. Shetty, Gary S. Bartley, David Yue-wei Lee