Patents by Inventor RUPERT RUTLEDGE
RUPERT RUTLEDGE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11802730Abstract: A remote system for monitoring and controlling one or more devices for use in the cryogenic processing of a sample is provided. A remote server capable of transmitting freezing profile data to one or more freezers, transmitting transportation profile data to one or more transportation devices, and transmitting thawing profile data to one or more thawing devices. The remote server is also capable of receiving detected data from the one or more freezers relating to the freezing of a sample in accordance with the freezing profile data, receiving detected data from the one or more transportation devices relating to the transportation of a sample in accordance with the transportation profile data, and receiving detected data from the one or more thawing machines relating to the thawing of a sample in accordance with the thawing profile data.Type: GrantFiled: November 20, 2019Date of Patent: October 31, 2023Assignee: Asymptote Ltd.Inventors: Alexander Nancekievill, Rupert Rutledge
-
Patent number: 11785940Abstract: A sample heating/cooling device (2) comprises a plurality of members (6) operable in use to heat and/or cool one or more samples (22). Each member (6) has a sample contact surface and is biased towards a resting position under the operation of a biasing means. The members (6) are movable independently of one another against said bias under the application of a force on the sample contact surface and so are able to conform to the shape of a sample placed on the members to provide a uniform heating/cooling profile. The members (6) may be mounted in a heating/cooling element (4) and adapted to conduct thermal energy between the sample (22) and the element (4). The device (2) is particularly suitable for thawing frozen sample bags having an irregular shape. A corresponding method is also described.Type: GrantFiled: April 12, 2021Date of Patent: October 17, 2023Assignee: CELL THERAPY CATAPULT LIMITEDInventors: Stuart Milne, Alex Nancekievill, Christopher Creasey, Stephen Lamb, Rupert Rutledge
-
Patent number: 11703275Abstract: A remote system for monitoring and controlling one or more devices for use in the cryogenic processing of a sample is provided. A remote server capable of transmitting freezing profile data to one or more freezers, transmitting transportation profile data to one or more transportation devices, and transmitting thawing profile data to one or more thawing devices. The remote server is also capable of receiving detected data from the one or more freezers relating to the freezing of a sample in accordance with the freezing profile data, receiving detected data from the one or more transportation devices relating to the transportation of a sample in accordance with the transportation profile data, and receiving detected data from the one or more thawing machines relating to the thawing of a sample in accordance with the thawing profile data.Type: GrantFiled: November 20, 2019Date of Patent: July 18, 2023Assignee: Asymptote Ltd.Inventors: Alexander Nancekievill, Rupert Rutledge
-
Patent number: 11650006Abstract: A remote system for monitoring and controlling one or more devices for use in the cryogenic processing of a sample is provided. A remote server capable of transmitting freezing profile data to one or more freezers, transmitting transportation profile data to one or more transportation devices, and transmitting thawing profile data to one or more thawing devices. The remote server is also capable of receiving detected data from the one or more freezers relating to the freezing of a sample in accordance with the freezing profile data, receiving detected data from the one or more transportation devices relating to the transportation of a sample in accordance with the transportation profile data, and receiving detected data from the one or more thawing machines relating to the thawing of a sample in accordance with the thawing profile data.Type: GrantFiled: November 20, 2019Date of Patent: May 16, 2023Assignee: ASYMPTOTE LTD.Inventors: Alexander Nancekievill, Rupert Rutledge
-
Patent number: 11441979Abstract: The invention provides a method of thawing a sample comprised in a container, the method comprising the steps of: a) calculating an agitation program as a function of either or both of the sample volume and the type of the container, and the ice fraction in the sample, and optionally the thermal conductivity of the sample container; b) agitating said sample according to the program to agitate at least one region of the sample; and c) changing the agitation program applied to at least one region of the sample in response to changes in the sample volume and/or sample ice fraction. The invention further provides a method of reducing shearing to cells during a method of agitation, and methods for thawing a sample wherein a sample container is differentially heated. An apparatus for use in the methods is also provided, as is an apparatus for thawing and/or cooling a sample which comprises a resilient vessel wall.Type: GrantFiled: December 4, 2015Date of Patent: September 13, 2022Assignee: ASYMPTOTE LTD.Inventors: Stuart Milne, Stephen Lamb, Christopher Creasey, Alex Nancekievill, Rupert Rutledge
-
Publication number: 20210235689Abstract: A sample heating/cooling device (2) comprises a plurality of members (6) operable in use to heat and/or cool one or more samples (22). Each member (6) has a sample contact surface and is biased towards a resting position under the operation of a biasing means. The members (6) are movable independently of one another against said bias under the application of a force on the sample contact surface and so are able to conform to the shape of a sample placed on the members to provide a uniform heating/cooling profile. The members (6) may be mounted in a heating/cooling element (4) and adapted to conduct thermal energy between the sample (22) and the element (4). The device (2) is particularly suitable for thawing frozen sample bags having an irregular shape. A corresponding method is also described.Type: ApplicationFiled: April 12, 2021Publication date: August 5, 2021Inventors: Stuart MILNE, Alex NANCEKIEVILL, Christopher CREASEY, Stephen LAMB, Rupert RUTLEDGE
-
Patent number: 11064694Abstract: A sample heating/cooling device comprises a plurality of members operable in use to heat and/or cool one or more samples. Each member has a sample contact surface and is biased towards a resting position under the operation of a biasing means. The members are movable independently of one another against said bias under the application of a force on the sample contact surface and so are able to conform to the shape of a sample placed on the members to provide a uniform heating/cooling profile. The members may be mounted in a heating/cooling element and adapted to conduct thermal energy between the sample and the element. The device is particularly suitable for thawing frozen sample bags having an irregular shape. A corresponding method is also described.Type: GrantFiled: March 9, 2017Date of Patent: July 20, 2021Assignee: CELL THERAPY CATAPULT LIMITEDInventors: Stuart Milne, Alex Nancekievill, Christopher Creasey, Stephen Lamb, Rupert Rutledge
-
Publication number: 20200116423Abstract: A remote system for monitoring and controlling one or more devices for use in the cryogenic processing of a sample is provided. A remote server capable of transmitting freezing profile data to one or more freezers, transmitting transportation profile data to one or more transportation devices, and transmitting thawing profile data to one or more thawing devices. The remote server is also capable of receiving detected data from the one or more freezers relating to the freezing of a sample in accordance with the freezing profile data, receiving detected data from the one or more transportation devices relating to the transportation of a sample in accordance with the transportation profile data, and receiving detected data from the one or more thawing machines relating to the thawing of a sample in accordance with the thawing profile data.Type: ApplicationFiled: November 20, 2019Publication date: April 16, 2020Inventors: Alexander Nancekievill, Rupert Rutledge
-
Publication number: 20200116422Abstract: A remote system for monitoring and controlling one or more devices for use in the cryogenic processing of a sample is provided. A remote server capable of transmitting freezing profile data to one or more freezers, transmitting transportation profile data to one or more transportation devices, and transmitting thawing profile data to one or more thawing devices. The remote server is also capable of receiving detected data from the one or more freezers relating to the freezing of a sample in accordance with the freezing profile data, receiving detected data from the one or more transportation devices relating to the transportation of a sample in accordance with the transportation profile data, and receiving detected data from the one or more thawing machines relating to the thawing of a sample in accordance with the thawing profile data.Type: ApplicationFiled: November 20, 2019Publication date: April 16, 2020Inventors: Alexander Nancekievill, Rupert Rutledge
-
Publication number: 20200103162Abstract: A remote system for monitoring and controlling one or more devices for use in the cryogenic processing of a sample is provided. A remote server capable of transmitting freezing profile data to one or more freezers, transmitting transportation profile data to one or more transportation devices, and transmitting thawing profile data to one or more thawing devices. The remote server is also capable of receiving detected data from the one or more freezers relating to the freezing of a sample in accordance with the freezing profile data, receiving detected data from the one or more transportation devices relating to the transportation of a sample in accordance with the transportation profile data, and receiving detected data from the one or more thawing machines relating to the thawing of a sample in accordance with the thawing profile data.Type: ApplicationFiled: November 20, 2019Publication date: April 2, 2020Inventors: Alexander Nancekievill, Rupert Rutledge
-
Publication number: 20190383554Abstract: A remote system for monitoring and controlling one or more devices for use in the cryogenic processing of a sample is provided. A remote server (130) is provided, capable of transmitting freezing profile data to one or more freezers (101, . . . , 10n), transmitting transportation profile data to one or more transportation devices, and transmitting thawing profile data to one or more thawing devices. The remote server is also capable of receiving detected data from the one or more freezers relating to the freezing of a sample in accordance with the freezing profile data, receiving detected data from the one or more transportation devices relating to the transportation of a sample in accordance with the transportation profile data, and receiving detected data from the one or more thawing machines relating to the thawing of a sample in accordance with the thawing profile data.Type: ApplicationFiled: November 24, 2017Publication date: December 19, 2019Inventors: Alexander Nancekievill, Rupert Rutledge
-
Publication number: 20190075786Abstract: A sample heating/cooling device comprises a plurality of members operable in use to heat and/or cool one or more samples. Each member has a sample contact surface and is biased towards a resting position under the operation of a biasing means. The members are movable independently of one another against said bias under the application of a force on the sample contact surface and so are able to conform to the shape of a sample placed on the members to provide a uniform heating/cooling profile. The members may be mounted in a heating/cooling element and adapted to conduct thermal energy between the sample and the element. The device is particularly suitable for thawing frozen sample bags having an irregular shape. A corresponding method is also described.Type: ApplicationFiled: March 9, 2017Publication date: March 14, 2019Inventors: Stuart MILNE, Alex NANCEKIEVILL, Christopher CREASEY, Stephen LAMB, Rupert RUTLEDGE
-
Publication number: 20190003939Abstract: The invention provides a method of thawing a sample comprised in a container, the method comprising the steps of: a) calculating an agitation program as a function of either or both of the sample volume and the type of the container, and the ice fraction in the sample, and optionally the thermal conductivity of the sample container; b) agitating said sample according to the program to agitate at least one region of the sample; and c) changing the agitation program applied to at least one region of the sample in response to changes in the sample volume and/or sample ice fraction. The invention further provides a method of reducing shearing to cells during a method of agitation, and methods for thawing a sample wherein a sample container is differentially heated. An apparatus for use in the methods is also provided, as is an apparatus for thawing and/or cooling a sample which comprises a resilient vessel wall.Type: ApplicationFiled: December 4, 2015Publication date: January 3, 2019Inventors: STUART MILNE, STEPHEN LAMB, CHRISTOPHER CREASEY, ALEX NANCEKIEVILL, RUPERT RUTLEDGE