Patents by Inventor RUPERT RUTLEDGE

RUPERT RUTLEDGE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11802730
    Abstract: A remote system for monitoring and controlling one or more devices for use in the cryogenic processing of a sample is provided. A remote server capable of transmitting freezing profile data to one or more freezers, transmitting transportation profile data to one or more transportation devices, and transmitting thawing profile data to one or more thawing devices. The remote server is also capable of receiving detected data from the one or more freezers relating to the freezing of a sample in accordance with the freezing profile data, receiving detected data from the one or more transportation devices relating to the transportation of a sample in accordance with the transportation profile data, and receiving detected data from the one or more thawing machines relating to the thawing of a sample in accordance with the thawing profile data.
    Type: Grant
    Filed: November 20, 2019
    Date of Patent: October 31, 2023
    Assignee: Asymptote Ltd.
    Inventors: Alexander Nancekievill, Rupert Rutledge
  • Patent number: 11785940
    Abstract: A sample heating/cooling device (2) comprises a plurality of members (6) operable in use to heat and/or cool one or more samples (22). Each member (6) has a sample contact surface and is biased towards a resting position under the operation of a biasing means. The members (6) are movable independently of one another against said bias under the application of a force on the sample contact surface and so are able to conform to the shape of a sample placed on the members to provide a uniform heating/cooling profile. The members (6) may be mounted in a heating/cooling element (4) and adapted to conduct thermal energy between the sample (22) and the element (4). The device (2) is particularly suitable for thawing frozen sample bags having an irregular shape. A corresponding method is also described.
    Type: Grant
    Filed: April 12, 2021
    Date of Patent: October 17, 2023
    Assignee: CELL THERAPY CATAPULT LIMITED
    Inventors: Stuart Milne, Alex Nancekievill, Christopher Creasey, Stephen Lamb, Rupert Rutledge
  • Patent number: 11703275
    Abstract: A remote system for monitoring and controlling one or more devices for use in the cryogenic processing of a sample is provided. A remote server capable of transmitting freezing profile data to one or more freezers, transmitting transportation profile data to one or more transportation devices, and transmitting thawing profile data to one or more thawing devices. The remote server is also capable of receiving detected data from the one or more freezers relating to the freezing of a sample in accordance with the freezing profile data, receiving detected data from the one or more transportation devices relating to the transportation of a sample in accordance with the transportation profile data, and receiving detected data from the one or more thawing machines relating to the thawing of a sample in accordance with the thawing profile data.
    Type: Grant
    Filed: November 20, 2019
    Date of Patent: July 18, 2023
    Assignee: Asymptote Ltd.
    Inventors: Alexander Nancekievill, Rupert Rutledge
  • Patent number: 11650006
    Abstract: A remote system for monitoring and controlling one or more devices for use in the cryogenic processing of a sample is provided. A remote server capable of transmitting freezing profile data to one or more freezers, transmitting transportation profile data to one or more transportation devices, and transmitting thawing profile data to one or more thawing devices. The remote server is also capable of receiving detected data from the one or more freezers relating to the freezing of a sample in accordance with the freezing profile data, receiving detected data from the one or more transportation devices relating to the transportation of a sample in accordance with the transportation profile data, and receiving detected data from the one or more thawing machines relating to the thawing of a sample in accordance with the thawing profile data.
    Type: Grant
    Filed: November 20, 2019
    Date of Patent: May 16, 2023
    Assignee: ASYMPTOTE LTD.
    Inventors: Alexander Nancekievill, Rupert Rutledge
  • Patent number: 11441979
    Abstract: The invention provides a method of thawing a sample comprised in a container, the method comprising the steps of: a) calculating an agitation program as a function of either or both of the sample volume and the type of the container, and the ice fraction in the sample, and optionally the thermal conductivity of the sample container; b) agitating said sample according to the program to agitate at least one region of the sample; and c) changing the agitation program applied to at least one region of the sample in response to changes in the sample volume and/or sample ice fraction. The invention further provides a method of reducing shearing to cells during a method of agitation, and methods for thawing a sample wherein a sample container is differentially heated. An apparatus for use in the methods is also provided, as is an apparatus for thawing and/or cooling a sample which comprises a resilient vessel wall.
    Type: Grant
    Filed: December 4, 2015
    Date of Patent: September 13, 2022
    Assignee: ASYMPTOTE LTD.
    Inventors: Stuart Milne, Stephen Lamb, Christopher Creasey, Alex Nancekievill, Rupert Rutledge
  • Publication number: 20210235689
    Abstract: A sample heating/cooling device (2) comprises a plurality of members (6) operable in use to heat and/or cool one or more samples (22). Each member (6) has a sample contact surface and is biased towards a resting position under the operation of a biasing means. The members (6) are movable independently of one another against said bias under the application of a force on the sample contact surface and so are able to conform to the shape of a sample placed on the members to provide a uniform heating/cooling profile. The members (6) may be mounted in a heating/cooling element (4) and adapted to conduct thermal energy between the sample (22) and the element (4). The device (2) is particularly suitable for thawing frozen sample bags having an irregular shape. A corresponding method is also described.
    Type: Application
    Filed: April 12, 2021
    Publication date: August 5, 2021
    Inventors: Stuart MILNE, Alex NANCEKIEVILL, Christopher CREASEY, Stephen LAMB, Rupert RUTLEDGE
  • Patent number: 11064694
    Abstract: A sample heating/cooling device comprises a plurality of members operable in use to heat and/or cool one or more samples. Each member has a sample contact surface and is biased towards a resting position under the operation of a biasing means. The members are movable independently of one another against said bias under the application of a force on the sample contact surface and so are able to conform to the shape of a sample placed on the members to provide a uniform heating/cooling profile. The members may be mounted in a heating/cooling element and adapted to conduct thermal energy between the sample and the element. The device is particularly suitable for thawing frozen sample bags having an irregular shape. A corresponding method is also described.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: July 20, 2021
    Assignee: CELL THERAPY CATAPULT LIMITED
    Inventors: Stuart Milne, Alex Nancekievill, Christopher Creasey, Stephen Lamb, Rupert Rutledge
  • Publication number: 20200116423
    Abstract: A remote system for monitoring and controlling one or more devices for use in the cryogenic processing of a sample is provided. A remote server capable of transmitting freezing profile data to one or more freezers, transmitting transportation profile data to one or more transportation devices, and transmitting thawing profile data to one or more thawing devices. The remote server is also capable of receiving detected data from the one or more freezers relating to the freezing of a sample in accordance with the freezing profile data, receiving detected data from the one or more transportation devices relating to the transportation of a sample in accordance with the transportation profile data, and receiving detected data from the one or more thawing machines relating to the thawing of a sample in accordance with the thawing profile data.
    Type: Application
    Filed: November 20, 2019
    Publication date: April 16, 2020
    Inventors: Alexander Nancekievill, Rupert Rutledge
  • Publication number: 20200116422
    Abstract: A remote system for monitoring and controlling one or more devices for use in the cryogenic processing of a sample is provided. A remote server capable of transmitting freezing profile data to one or more freezers, transmitting transportation profile data to one or more transportation devices, and transmitting thawing profile data to one or more thawing devices. The remote server is also capable of receiving detected data from the one or more freezers relating to the freezing of a sample in accordance with the freezing profile data, receiving detected data from the one or more transportation devices relating to the transportation of a sample in accordance with the transportation profile data, and receiving detected data from the one or more thawing machines relating to the thawing of a sample in accordance with the thawing profile data.
    Type: Application
    Filed: November 20, 2019
    Publication date: April 16, 2020
    Inventors: Alexander Nancekievill, Rupert Rutledge
  • Publication number: 20200103162
    Abstract: A remote system for monitoring and controlling one or more devices for use in the cryogenic processing of a sample is provided. A remote server capable of transmitting freezing profile data to one or more freezers, transmitting transportation profile data to one or more transportation devices, and transmitting thawing profile data to one or more thawing devices. The remote server is also capable of receiving detected data from the one or more freezers relating to the freezing of a sample in accordance with the freezing profile data, receiving detected data from the one or more transportation devices relating to the transportation of a sample in accordance with the transportation profile data, and receiving detected data from the one or more thawing machines relating to the thawing of a sample in accordance with the thawing profile data.
    Type: Application
    Filed: November 20, 2019
    Publication date: April 2, 2020
    Inventors: Alexander Nancekievill, Rupert Rutledge
  • Publication number: 20190383554
    Abstract: A remote system for monitoring and controlling one or more devices for use in the cryogenic processing of a sample is provided. A remote server (130) is provided, capable of transmitting freezing profile data to one or more freezers (101, . . . , 10n), transmitting transportation profile data to one or more transportation devices, and transmitting thawing profile data to one or more thawing devices. The remote server is also capable of receiving detected data from the one or more freezers relating to the freezing of a sample in accordance with the freezing profile data, receiving detected data from the one or more transportation devices relating to the transportation of a sample in accordance with the transportation profile data, and receiving detected data from the one or more thawing machines relating to the thawing of a sample in accordance with the thawing profile data.
    Type: Application
    Filed: November 24, 2017
    Publication date: December 19, 2019
    Inventors: Alexander Nancekievill, Rupert Rutledge
  • Publication number: 20190075786
    Abstract: A sample heating/cooling device comprises a plurality of members operable in use to heat and/or cool one or more samples. Each member has a sample contact surface and is biased towards a resting position under the operation of a biasing means. The members are movable independently of one another against said bias under the application of a force on the sample contact surface and so are able to conform to the shape of a sample placed on the members to provide a uniform heating/cooling profile. The members may be mounted in a heating/cooling element and adapted to conduct thermal energy between the sample and the element. The device is particularly suitable for thawing frozen sample bags having an irregular shape. A corresponding method is also described.
    Type: Application
    Filed: March 9, 2017
    Publication date: March 14, 2019
    Inventors: Stuart MILNE, Alex NANCEKIEVILL, Christopher CREASEY, Stephen LAMB, Rupert RUTLEDGE
  • Publication number: 20190003939
    Abstract: The invention provides a method of thawing a sample comprised in a container, the method comprising the steps of: a) calculating an agitation program as a function of either or both of the sample volume and the type of the container, and the ice fraction in the sample, and optionally the thermal conductivity of the sample container; b) agitating said sample according to the program to agitate at least one region of the sample; and c) changing the agitation program applied to at least one region of the sample in response to changes in the sample volume and/or sample ice fraction. The invention further provides a method of reducing shearing to cells during a method of agitation, and methods for thawing a sample wherein a sample container is differentially heated. An apparatus for use in the methods is also provided, as is an apparatus for thawing and/or cooling a sample which comprises a resilient vessel wall.
    Type: Application
    Filed: December 4, 2015
    Publication date: January 3, 2019
    Inventors: STUART MILNE, STEPHEN LAMB, CHRISTOPHER CREASEY, ALEX NANCEKIEVILL, RUPERT RUTLEDGE