Patents by Inventor Rupesh Dash

Rupesh Dash has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of a truncated CCN1 promoter for cancer diagnostics, therapeutics and theranostics
    Patent number: 9750823
    Abstract: Recombinant vectors in which expression of one or more elements (e.g. genes required for viral replication, detectable imaging agents, therapeutic agents, etc.) is driven by a truncated CCN 1 cancer selective promoter (tCCN1-Prom) are provided, as are cells and transgenic animals that contain such vectors. The vectors are used in cancer therapy and/or diagnostics, and the transgenic mice are used to monitor cancer progression, e.g. in screening assays.
    Type: Grant
    Filed: June 4, 2014
    Date of Patent: September 5, 2017
    Inventors: Paul B. Fisher, Swadesh K. Das, Rupesh Dash, Devanand Sarkar, Siddik Sarkar, Jolene Windle
  • USE OF A TRUNCATED CCN1 PROMOTER FOR CANCER DIAGNOSTICS, THERAPEUTICS AND THERANOSTICS
    Publication number: 20160101193
    Abstract: Recombinant vectors in which expression of one or more elements (e.g. genes required for viral replication, detectable imaging agents, therapeutic agents, etc.) is driven by a truncated CCN 1 cancer selective promoter (tCCN1-Prom) are provided, as are cells and transgenic animals that contain such vectors. The vectors are used in cancer therapy and/or diagnostics, and the transgenic mice are used to monitor cancer progression, e.g. in screening assays.
    Type: Application
    Filed: June 4, 2014
    Publication date: April 14, 2016
    Inventors: Paul B. Fisher, Swadesh K. Das, Rupesh Dash, Devanand Sarkar, Siddik Sarkar, Jolene Windle
  • MICROBUBBLE ASSISTED VIRAL DELIVERY
    Publication number: 20120195935
    Abstract: Microbubble-assisted delivery of viruses is disclosed. In particular, methods for targeting a virus to cancer cells in an immunocompetent animal by administering a selectively replicating virus to the immunocompetent animal and disrupting the microbubbles in a location of the animal comprising cancer cells are provided. The virus is encompassed in a suspension of microbubbles, and the surface of the suspension does not include any virus. A suspension of microbubbles comprising a selectively replicating virus that is encompassed in a suspension of microbubbles, which does not include any virus on the surface of the suspension, is also provided.
    Type: Application
    Filed: July 27, 2010
    Publication date: August 2, 2012
    Applicant: VIRGINIA COMMONWEALTH UNIVERSITY
    Inventors: Paul B. Fisher, Devanand Sarkar, Rupesh Dash, Belal Mohammed Azab, Xiang-Yang Wang, Pier Paolo Claudio