Patents by Inventor Rupinder Bharmi
Rupinder Bharmi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210020294Abstract: A method for managing a treatment is provided. The method is under control of a processor. The method obtains a body generated analyte (BGA) indicative of a malnutrition state (MS) characteristic of interest (COI) of a patient and obtains implantable medical device (IMD) data indicative of a physiologic COI from the patient. The method assigns a health risk index based on the MS COI and the physiologic COI. The health risk index is indicative of a chronic disease state and malnutrition state currently exhibited by the patient. The method generates a treatment notification based on the health risk index.Type: ApplicationFiled: July 16, 2020Publication date: January 21, 2021Inventors: Rupinder Bharmi, Rahul Agarwal, Philip B. Adamson, Heidi Hellman, Nirav Dalal
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Publication number: 20200242566Abstract: A system for prioritizing patients for clinician management that includes one or more processors configured to execute program instructions. When executed the one or more processors determine a risk score for a patient, alter the risk score based on patient based parameters to determine a priority score of the patient, compare the priority score of the patient to priority scores of other patients, assign a rank to the patient based on the comparison of the priority score of the patient to the priority scores of the other patients, and schedule an appointment for the patient based on the rank.Type: ApplicationFiled: January 30, 2019Publication date: July 30, 2020Inventors: Rahul Agarwal, Rupinder Bharmi, Matthew S.D. Kerr, Phillip B. Adamson, Nirav Dalal
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Publication number: 20190192855Abstract: Described herein are methods, devices, and systems for treating human anemia. The methods, devices, and systems generally include monitoring a patient's hemoglobin level and at least one of autonomic balance and inflammatory state to determine the etiology of the anemic state, modulating at least one of a sympathetic or parasympathetic nerve based on the cause of the anemia, monitoring for changes in the patient's cardiac activity and state of inflammation, and hemoglobin level. An external neurostimulation system is describes, and well as a chronic implantable system. A method for treating a patient for anemia in conjunction with a renal denervation ablation catheter is also disclosed.Type: ApplicationFiled: December 21, 2018Publication date: June 27, 2019Inventors: Rupinder Bharmi, Stuart Rosenberg, Ryan Rooke, Edward Karst, Taraneh Ghaffari Farazi
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Publication number: 20190133518Abstract: The present disclosure is directed to methods and systems for determining diuretic response profiles. The methods and systems include obtaining pulmonary artery pressure measurements from a patient prior to and after medication has been taken by the patient, comparing the pressures, and then determining the medication response profile in the patient. The methods and systems further include modifying the medication, withdrawing the medication, and/or identifying a non-responsive patient.Type: ApplicationFiled: November 3, 2017Publication date: May 9, 2019Inventors: Rupinder Bharmi, Philip B. Adamson, Rahul Agarwal
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Patent number: 10201705Abstract: Described herein are methods, devices, and systems for treating human anemia. The methods, devices, and systems generally include monitoring a patient's hemoglobin level and at least one of autonomic balance and inflammatory state to determine the etiology of the anemic state, modulating at least one of a sympathetic or parasympathetic nerve based on the cause of the anemia, monitoring for changes in the patient's cardiac activity and state of inflammation, and hemoglobin level. An external neurostimulation system is describes, and well as a chronic implantable system. A method for treating a patient for anemia in conjunction with a renal denervation ablation catheter is also disclosed.Type: GrantFiled: February 17, 2017Date of Patent: February 12, 2019Assignee: Pacesetter, Inc.Inventors: Rupinder Bharmi, Stuart Rosenberg, Ryan Rooke, Edward Karst, Taraneh Ghaffari Farazi
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Publication number: 20170165488Abstract: Described herein are methods, devices, and systems for treating human anemia. The methods, devices, and systems generally include monitoring a patient's hemoglobin level and at least one of autonomic balance and inflammatory state to determine the etiology of the anemic state, modulating at least one of a sympathetic or parasympathetic nerve based on the cause of the anemia, monitoring for changes in the patient's cardiac activity and state of inflammation, and hemoglobin level. An external neurostimulation system is describes, and well as a chronic implantable system. A method for treating a patient for anemia in conjunction with a renal denervation ablation catheter is also disclosed.Type: ApplicationFiled: February 17, 2017Publication date: June 15, 2017Inventors: Rupinder Bharmi, Stuart Rosenberg, Ryan Rooke, Edward Karst, Taraneh Ghaffari Farazi
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Patent number: 9610444Abstract: Described herein are methods, devices, and systems for treating human anemia. The methods, devices, and systems generally include monitoring a patients hemoglobin level and at least one of autonomic balance and inflammatory state to determine the etiology of the anemic state, modulating at least one of a sympathetic or parasympathetic nerve based on the cause of the anemia, monitoring for changes in the patients cardiac activity and state of inflammation, and hemoglobin level. An external neurostimulation system is describes, and well as a chronic implantable system. A method for treating a patient for anemia in conjunction with a renal denervation ablation catheter is also disclosed.Type: GrantFiled: March 18, 2014Date of Patent: April 4, 2017Assignee: Pacesetter, Inc.Inventors: Rupinder Bharmi, Stuart Rosenberg, Ryan Rooke, Edward Karst, Taraneh Ghaffari Farazi
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Publication number: 20160325101Abstract: Diastolic function is monitored within a patient based on dynamic cardiogenic impedance as measured by a pacemaker or other implantable medical device. In one example, the device uses ventricular cardiogenic impedance values to detect E-wave parameters representative of passive filling of the ventricles. Atrial cardiogenic impedance values are used to detect A-wave parameters representative of active filling of the ventricles. Diastolic function is then assessed or evaluated based on the E-wave and A-wave parameters. Various functions of the implantable device are then controlled based on the assessment of diastolic function, such as by adjusting atrioventricular delay parameters to improve diastolic function. In some examples, the detection of E- and A-wave parameters is achieved by aligning impedance signals to atrial activation, and separately to ventricular activation, during asynchronous VOO pacing or while artificially inducing a 2:1 block.Type: ApplicationFiled: July 15, 2016Publication date: November 10, 2016Inventors: Stuart Rosenberg, Kritika Gupta, Riddhi Shah, Rupinder Bharmi, Edward Karst, Gene A. Bornzin
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Patent number: 9433792Abstract: Diastolic function is monitored within a patient based on dynamic cardiogenic impedance as measured by a pacemaker or other implantable medical device. In one example, the device uses ventricular cardiogenic impedance values to detect E-wave parameters representative of passive filling of the ventricles. Atrial cardiogenic impedance values are used to detect A-wave parameters representative of active filling of the ventricles. Diastolic function is then assessed or evaluated based on the E-wave and A-wave parameters. Various functions of the implantable device are then controlled based on the assessment of diastolic function, such as by adjusting atrioventricular delay parameters to improve diastolic function. In some examples, the detection of E- and A-wave parameters is achieved by aligning impedance signals to atrial activation, and separately to ventricular activation, during asynchronous VOO pacing or while artificially inducing a 2:1 block.Type: GrantFiled: May 21, 2013Date of Patent: September 6, 2016Assignee: PACESETTER, INC.Inventors: Stuart Rosenberg, Kritika Gupta, Riddhi Shah, Rupinder Bharmi, Edward Karst, Gene A. Bornzin
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Patent number: 9433793Abstract: A system and method provide precise detection of the time of occurrence of a cardiac event of a heart. The method comprises the steps of sensing electrical activity of the heart to generate an electrogram of the heart and applying the electrogram to an event detector having a plurality of spaced apart thresholds. The thresholds are selected such that the electrogram has an amplitude for crossing at least one of the thresholds. The method further comprises determining a characteristic identifying feature of the electrogram at each threshold crossing of the electrogram, comparing the determined characteristic identifying features to an electrogram template, and identifying the time of occurrence of the cardiac event based upon the comparison.Type: GrantFiled: November 3, 2008Date of Patent: September 6, 2016Assignee: Pacesetter, Inc.Inventors: Rupinder Bharmi, Jeffery D. Snell
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Publication number: 20160206883Abstract: A system and method for current steering a neurostimulation signal is provided. The system and method provide a lead coupled to an implantable pulse generator (IPG). The lead may include a plurality of electrodes. The lead may be configured to be implanted at a target position proximate to tissue of interest. The system and method program the IPG to deliver at least a first pulse train to a first electrode and a second pulse train to a second electrode. The first and second pulse trains are interleaved with one another such that the first and second pulse trains form an activation current density distribution steered to overlay the tissue of interest.Type: ApplicationFiled: January 19, 2015Publication date: July 21, 2016Inventors: Gene A. Bornzin, Lalit Venkatesan, Yelena Nabutovsky, Riddhi Shah, Rupinder Bharmi, Edward Karst, Alexander Kent, Xiaoyi Min
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Patent number: 9247895Abstract: A method for performing deep brain stimulation (DBS) therapy may include determining a location of a target area of a brain, forming a burr hole through a skull of a patient based on the location the target area, positioning one or more reference members on or within the brain through the burr hole, and acquiring at least one image of the brain having the one or more reference members with at least one imaging sub-system.Type: GrantFiled: March 21, 2014Date of Patent: February 2, 2016Assignee: Pacesetter, Inc.Inventors: Lalit Venkatesan, Gene A. Bornzin, Rupinder Bharmi, Yelena Nabutovsky, Riddhi Shah, Kevin Wilson
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Patent number: 9198614Abstract: A method and system are provided for characterizing chamber specific function. The method and system comprise collecting cardiac signals associated with asynchronous timing between first and second chambers of the heart; collecting dynamic impedance (DI) data along a chamber-specific function (CSF) vector to form a DI data set, the DI data set collected during a collection window that is temporally aligned based on a timing feature of interest (FOI); repeating the collection operations over multiple cardiac cycles (CC) to obtain an ensemble of DI data sets; and combining the ensemble of DI data sets to form a composite DI data set that is coupled to a chamber functional mechanic of interest (FMOI) associated with the first chamber and decoupled from functional mechanics associated with the second chamber; and analyzing the composite DI data set to obtain a CSF indicator associated with the chamber FMOI of the first chamber.Type: GrantFiled: September 11, 2013Date of Patent: December 1, 2015Assignee: Pacesetter, Inc.Inventors: Kritika Gupta, Rupinder Bharmi, Bruce A. Morley, Laurence S. Sloman, Wenbo Hou, Xiaoyi Min, Riddhi Shah, Edward Karst, Gene A. Bornzin
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Patent number: 9199088Abstract: A system and method enables precise detection of the time of occurrence of a cardiac event of a heart. The method includes the steps of sensing electrical activity of the heart to generate an electrogram signal including the cardiac event, storing the electrogram signal, correlating the electrogram signal with an electrogram template, and identifying the time of occurrence of the cardiac event based upon the correlation.Type: GrantFiled: November 3, 2008Date of Patent: December 1, 2015Assignee: Pacesetter, Inc.Inventors: Rupinder Bharmi, Jeffery D. Snell
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Patent number: 9179846Abstract: A method and system are provided for characterizing cardiac function. The method and system comprise collecting cardiac signals associated with electrical or mechanical behavior of a heart over at least one cardiac cycle; identifying a timing feature of interest (FOI) from the cardiac signals; collecting dynamic impedance (DI) data over at least one cardiac cycle (CC), designated by the timing FOI, along at least one of i) a venous return (VR) vector or ii) a right ventricular function (RVF) vector; and analyzing at least one morphologic characteristic from the DI data based on at least one of i) a VR-DI correlation metric to obtain a VR indicator associated with the CC or ii) a RVF-DI correlation metric to obtain a RVF indicator associated with CC.Type: GrantFiled: March 15, 2013Date of Patent: November 10, 2015Assignee: PACESETTER, INC.Inventors: Wenbo Hou, Kritika Gupta, Bruce A. Morley, Laurence S. Sloman, Rupinder Bharmi, Xiaoyi Min, Riddhi Shah, Gene A. Bornzin, Edward Karst
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Publication number: 20150265180Abstract: A method for performing deep brain stimulation (DBS) therapy may include determining a location of a target area of a brain, forming a burr hole through a skull of a patient based on the location the target area, positioning one or more reference members on or within the brain through the burr hole, and acquiring at least one image of the brain having the one or more reference members with at least one imaging sub-system.Type: ApplicationFiled: March 21, 2014Publication date: September 24, 2015Applicant: PACESETTER, INC.Inventors: Lalit Venkatesan, Gene A. Bornzin, Rupinder Bharmi, Yelena Nabutovsky, Riddhi Shah, Kevin Wilson
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Patent number: 9095717Abstract: A method and system are provided to analyze valve related timing and monitor heart failure. The method and system comprise collecting cardiac signals associated with an atrial chamber of interest; collecting dynamic impedance (DI) data along an atria-function focused (AFF) vector to form a DI data set, the DI data set including information corresponding to a mechanical function (MF) of a valve associated with the atrial chamber of interest; identifying, from the cardiac signals, an intra-atrial conduction timing (IACT) associated with the atrial chamber of interest; estimating an MF landmark at which the mechanical function of the valve occurs based on the DI data set; analyzing a timing delay between the MF landmark and the IACT; and adjusting a therapy, based on the timing delay, to encourage atrial contribution to ventricular filling.Type: GrantFiled: August 26, 2013Date of Patent: August 4, 2015Assignee: PACESETTER, INC.Inventors: Xiaoyi Min, Rupinder Bharmi, Wenbo Hou, Edward Karst, Kritika Gupta, Risshi Shah
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Patent number: 9026208Abstract: An implantable medical device, comprised of at least one lead configured to be located proximate to a heart, the at least one lead including electrodes, at least a portion of the electrodes configured to sense cardiac activity. A therapy module configured to control delivery of pacing pulses in accordance with a therapy timing and based on the cardiac sensed activity sensed. Cardiac impedance (CI) sensor circuitry configured to be coupled to at least a first combination of the electrodes to sense cardiac impedance (CI), the CI sensor circuitry generating an impedance data stream associated with a corresponding CI sensing vector.Type: GrantFiled: February 25, 2013Date of Patent: May 5, 2015Assignee: Pacesetter, Inc.Inventors: Bruce A. Morley, Gene A. Bornzin, Kritika Gupta, Rupinder Bharmi, Laurence S. Sloman, Edward Karst, Wenbo Hou, Riddhi Shah
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Patent number: 8989852Abstract: Techniques are provided for detecting and distinguishing stroke and cardiac ischemia based on electrocardiac signals. In one example, the device senses atrial and ventricular signals within the patient along a set of unipolar sensing vectors and identifies certain morphological features within the signals such as PR intervals, ST intervals, QT intervals, T-waves, etc. The device detects changes, if any, within the morphological features such as significant shifts in ST interval elevation or an inversion in T-wave shape, which are indicative of stroke or cardiac ischemia. By selectively comparing changes detected along different unipolar sensing vectors, the device distinguishes or discriminates stroke from cardiac ischemia within the patient. The discrimination may be corroborated using various physiological and hemodynamic parameters. In some examples, the device further identifies the location of the ischemia within the heart.Type: GrantFiled: August 10, 2011Date of Patent: March 24, 2015Assignee: Pacesetter, Inc.Inventors: Jong Gill, Rupinder Bharmi, Edward Karst, Ryan Rooke, Riddhi Shah, Fujian Qu, Gene A. Bornzin, Taraneh G. Farazi, Euljoon Park
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Patent number: 8983604Abstract: Techniques are provided for controlling spinal cord stimulation (SCS) or other forms of neurostimulation. Far-field cardiac electrical signals are sensed using a lead of the SCS device and neurostimulation is selectively delivering using a set of adjustable SCS control parameters. Parameters representative of cardiac rhythm are derived from the far-field cardiac electrical signals. The parameters representative of cardiac rhythm are correlated with SCS control parameters to thereby map neurostimulation control settings to cardiac rhythm parameters. The delivery of further neurostimulation is then controlled based on the mapping of neurostimulation control settings to cardiac rhythm parameters to, for example, address any cardiovascular disorders detected based on the far-field cardiac signals. In this manner, a closed loop control system is provided to automatically adjust SCS control parameters to respond to changes in cardiac rhythm such as changes associated with ischemia, arrhythmia or heart failure.Type: GrantFiled: March 15, 2013Date of Patent: March 17, 2015Assignee: Pacesetter, Inc.Inventors: Allen Keel, Stuart Rosenberg, Rupinder Bharmi, Kyungmoo Ryu, Edward Karst, Fujian Qu, Xiaoyi Min, Yelena Nabutovsky