Patents by Inventor Ruslan Faridovich Masgutov

Ruslan Faridovich Masgutov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Codon-optimized recombinant plasmid, method of stimulating peripheral nerve regeneration, and method of treating nerve damage in humans
    Patent number: 10434145
    Abstract: Provided is a method for treating a peripheral nervous system damage or injury, or for regenerating peripheral nervous system tissue that involves administering to a subject in need thereof a vector that comprises polynucleotide sequences that encode a modified vascular endothelia growth factor (VEGF) and a fibroblast growth factor (FGF2) and further a polynucleotide that encodes resistance to kanamycin. A gene-therapeutic structure encoding modified vascular endothelial growth factors (VEGF) and (FGF-2) is also provided. The gene-therapeutic structure can be administered directly to a damaged nerve and paraneural tissues both in intraoperative and post-operative period to stimulate peripheral nerve regeneration. The structure and method significantly advance existing methods for reconstructive treatment for damaged peripheral nerves.
    Type: Grant
    Filed: July 18, 2017
    Date of Patent: October 8, 2019
    Assignee: “NEXTGEN” COMPANY LIMITED
    Inventors: Artur Aleksandrovich Isaev, Albert Anatolyevich Rizvanov, Ruslan Faridovich Masgutov, Aleksei Andreevich Bogov, Ilnur Ildusovich Salafutdinov, Roman Vadimovich Deev, Ilya Yadigerovich Bozo, Igor Leonidovich Plaksa, Andrei Alekseevich Bogov, Valeriya Vladimirovna Solovyeva
  • CODON-OPTIMIZED RECOMBINANT PLASMID, METHOD OF STIMULATING PERIPHERAL NERVE REGENERATION, AND METHOD OF TREATING NERVE DAMAGE IN HUMANS
    Publication number: 20170319658
    Abstract: Provided is a method for treating a peripheral nervous system damage or injury, or for regenerating peripheral nervous system tissue that involves administering to a subject in need thereof a vector that comprises polynucleotide sequences that encode a modified vascular endothelia growth factor (VEGF) and a fibroblast growth factor (FGF2) and further a polynucleotide that encodes resistance to kanamycin. A gene-therapeutic structure encoding modified vascular endothelial growth factors (VEGF) and (FGF-2) is also provided. The gene-therapeutic structure can be administered directly to a damaged nerve and paraneural tissues both in intraoperative and post-operative period to stimulate peripheral nerve regeneration. The structure and method significantly advance existing methods for reconstructive treatment for damaged peripheral nerves.
    Type: Application
    Filed: July 18, 2017
    Publication date: November 9, 2017
    Applicant: "NEXTGEN" COMPANY LIMITED
    Inventors: Artur Aleksandrovich ISAEV, Albert Anatolyevich RIZVANOV, Ruslan Faridovich MASGUTOV, Aleksei Andreevich BOGOV, IInur IIdusovich SALAFUTDINOV, Roman Vadimovich DEEV, IIya Yadigerovich BOZO, Igor Leonidovich PLAKSA, Andrei Alekseevich BOGOV, Valeriya Vladimirovna SOLOVYEVA
  • CODON-OPTIMIZED RECOMBINANT PLASMID, METHOD OF STIMULATING PERIPHERAL NERVE REGENERATION, AND METHOD OF TREATING NERVE DAMAGE IN HUMANS
    Publication number: 20170189488
    Abstract: Provided is a method for treating a peripheral nervous system damage or injury, or for regenerating peripheral nervous system tissue that involves administering to a subject in need thereof a vector that comprises polynucleotide sequences that encode vascular endothelia growth factor (VEGF) and fibroblast growth factor (FGF2) and further a polynucleotide that encodes resistance to kanamycin. A gene-therapeutic structure coding vascular endothelial growth factor (VEGF) and (FGF-2) is also provided. The gene-therapeutic structure can be administered directly to a damaged nerve and paraneural tissues both in intraoperative and post-operative period to stimulate peripheral nerve regeneration. The structure and method significantly advance existing methods for reconstructive treatment for damaged peripheral nerves.
    Type: Application
    Filed: March 16, 2017
    Publication date: July 6, 2017
    Applicant: ''NEXTGEN'' COMPANY LIMITED
    Inventors: Artur Aleksandrovich ISAEV, Albert Anatolyevich Rizvanov, Ruslan Faridovich Masgutov, Aleksei Andreevich Bogov, IInur lldusovich Salafutdinov, Roman Vadimovich Deev, llya Yadigerovich Bozo, Igor Leonidovich Plaksa, Andrei Alekseevich Bogov