Abstract: The present description provides esterified fatty acid and/or tall oil compositions and their use as alternative plasticizers in adhesives formulations. These esters demonstrate similar or improved performance over adhesives industry standard plasticizers. The description also provides methods of manufacturing and using the same, for example, to improve or modify the performance of adhesive materials, such as, hot melt pressure sensitive adhesives and hygienic adhesives.

Abstract: The present description provides esterified fatty acid and/or tall oil compositions and their use as alternative plasticizers in adhesives formulations. These esters demonstrate similar or improved performance over adhesives industry standard plasticizers. The description also provides methods of manufacturing and using the same, for example, to improve or modify the performance of adhesive materials, such as, hot melt pressure sensitive adhesives and hygienic adhesives.

Abstract: Aliphatically modified rosin resins are prepared by reacting rosin esters with aliphatic monomers. These aliphatically modified rosin resins are compatible with metallocene catalyzed polyolefins and other aliphatic base polymers and are used as tackifiers in combination with metallocene catalyzed polyolefins and other aliphatic base polymers to form adhesive compositions for hot melt and pressure sensitive applications.

Abstract: Aliphatically modified rosin resins are prepared by reacting rosin esters with aliphatic monomers. These aliphatically modified rosin resins are compatible with metallocene catalyzed polyolefins and other aliphatic base polymers and are used as tackifiers in combination with metallocene catalyzed polyolefins and other aliphatic base polymers to form adhesive compositions for hot melt and pressure sensitive applications.

Abstract: This invention relates to a novel chemical process for the synthesis of 2-ethyoxycarbonylamino-5-(4-fluorobenzylamino)-nitrobenzene and its use in the preparation of 2-amino-4-(4-fluorobenzylamino)-1-ethoxycarbonylaminobenzene (retigabine/ezogabine) and its polymorphic forms thereof.

Abstract: This invention relates to a novel chemical process for the synthesis of 2-ethyoxycarbonylamino-5-(4-fluorobenzylamino)-nitrobenzene and its use in the preparation of 2-amino-4-(4-fluorobenzylamino)-1-ethoxycarbonylaminobenzene (retigabine/ezogabine) and its polymorphic forms thereof.

Abstract: The invention provides a process for preparing a compound of formula (I) and pharmaceutically acceptable derivatives thereof wherein: R0 and R1 are independently selected from H, halogen, C1-6alkyl, C1-6alkoxy, or C1-6alkoxy substituted by one or more fluorine atoms; R2 is H, C1-6alkyl, C1-6alkyl substituted by one or more fluorine atoms, C1-6alkoxy, C1-6hydroxyalkyl, SC1-6alkyl, C(O)H, C(O)C1-6alkyl, C1-6alkylsulfonyl, C1-6alkoxy substituted by one or more fluorine atoms, halogen, CN, CONR4R5, CO2H, CO2C1-6alkyl, or NHSO2R4; R3 is H or phenyl substituted by SO2C1-6alkyl or SO2NH2; R4 and R5 are independently selected from H, C1-6alkyl, phenyl, phenyl substituted by one or more atoms or groups R6, or together with the nitrogen atom to which they are attached form a saturated 4 to 8 membered ring R6 is halogen, C1-6alkyl, C1-6alkoxy or C1-6alkoxy substituted by one or more fluorine atoms; which comprises rearrangement of an azirine of formula (II)  wherein R0 to R

Abstract: The invention provides a process for preparing a compound of formula (I) and pharmaceutically acceptable derivatives thereof wherein: R0 and R1 are independently selected from H. halogen, C1-6alkyl, C1-6alkoxy. or C1-6alkoxy substituted by one or more fluorine atoms; R2 is H, C1-6alkyl. C1-6alkyl substituted by one or more fluorine atoms. C1-6alkoxy, C1-6hydroxyalkyl. SC1-6alkyl. C(O)H. C(O)C1-6alkyl. C1-6alkylsulfonyl. C1-6alkoxy substituted by one or more fluorine atoms, halogen.