Patents by Inventor Russell A. Baldocchi
Russell A. Baldocchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20180074066Abstract: Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.Type: ApplicationFiled: September 27, 2017Publication date: March 15, 2018Inventors: Brent S. GAYLORD, Glenn P. BARTHOLOMEW, Russell A. BALDOCCHI, Janice W. HONG, William H. HUISMAN, Yongchao LIANG, Trung NGUYEN, Lan T. TRAN, Jean M. WHEELER, Adrian Charles Vernon PALMER, Frank Peter UCKERT
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Publication number: 20180059117Abstract: Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.Type: ApplicationFiled: October 31, 2017Publication date: March 1, 2018Inventors: Brent S. Gaylord, Janice W. Hong, Tsu-Ju Fu, ChengJun Sun, Russell A. Baldocchi
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Publication number: 20170115298Abstract: Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.Type: ApplicationFiled: November 29, 2016Publication date: April 27, 2017Inventors: Brent S. Gaylord, Janice W. Hong, Tsu-Ju Fu, ChengJun Sun, Russell A. Baldocchi
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Patent number: 9547008Abstract: Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.Type: GrantFiled: August 7, 2015Date of Patent: January 17, 2017Assignee: Sirigen Inc.Inventors: Brent S. Gaylord, Glenn P. Bartholomew, Russell A. Baldocchi, Janice W. Hong, William H. Huisman, Yongchao Liang, Trung Nguyen, Lan T. Tran, Jean M. Wheeler, Adrian Charles Vernon Palmer, Frank Peter Uckert
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Publication number: 20160349267Abstract: Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.Type: ApplicationFiled: August 17, 2016Publication date: December 1, 2016Inventors: Brent S. GAYLORD, Glenn P. BARTHOLOMEW, Russell A. BALDOCCHI, Janice W. HONG, William H. HUISMAN, Yongchao LIANG, Trung NGUYEN, Lan T. TRAN, Jean M. WHEELER, Adrian Charles Vernon PALMER, Frank Peter UCKERT
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Publication number: 20160266132Abstract: Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.Type: ApplicationFiled: May 23, 2016Publication date: September 15, 2016Inventors: Brent S. Gaylord, Janice W. Hong, Tsu-Ju Fu, ChengJun Sun, Russell A. Baldocchi
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Patent number: 9383353Abstract: Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.Type: GrantFiled: June 17, 2014Date of Patent: July 5, 2016Assignee: Sirigen Inc.Inventors: Brent S. Gaylord, Janice W. Hong, Tsu-Ju Fu, ChengJun Sun, Russell Baldocchi
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Publication number: 20160025735Abstract: Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.Type: ApplicationFiled: August 7, 2015Publication date: January 28, 2016Inventors: Brent S. GAYLORD, Glenn P. BARTHOLOMEW, Russell A. BALDOCCHI, Janice W. HONG, William H. HUISMAN, Yongchao LIANG, Trung NGUYEN, Lan T. TRAN, Jean M. WHEELER, Adrian Charles Vernon PALMER, Frank Peter UCKERT
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Publication number: 20150309016Abstract: Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.Type: ApplicationFiled: June 17, 2014Publication date: October 29, 2015Inventors: Brent S. GAYLORD, Janice W. HONG, Tsu-Ju FU, ChengJun SUN, Russell BALDOCCHI
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Patent number: 9139869Abstract: Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.Type: GrantFiled: September 5, 2013Date of Patent: September 22, 2015Assignee: Sirigen Inc.Inventors: Brent S. Gaylord, Glenn P. Bartholomew, Russell A. Baldocchi, Janice W. Hong, William H. Huisman, Yongchao Liang, Trung Nguyen, Lan P. Tran, Jean M. Wheeler, Adrian Charles Vernon Palmer, Frank Peter Uckert
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Patent number: 8802450Abstract: Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.Type: GrantFiled: August 1, 2011Date of Patent: August 12, 2014Assignee: Sirigen, Inc.Inventors: Brent S. Gaylord, Janice W. Hong, Tsu-Ju Fu, Cheng-Jun Sun, Russell Baldocchi
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Publication number: 20140206557Abstract: Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.Type: ApplicationFiled: September 5, 2013Publication date: July 24, 2014Applicant: Sirigen Inc.Inventors: Brent S. GAYLORD, Glenn P. BARTHOLOMEW, Russell A. BALDOCCHI, Janice W. HONG, William H. HUISMAN, Yongchao LIANG, Trung NGUYEN, Lan P. TRAN, Jean M. WHEELER, Adrian Charles Vernon PALMER, Frank Peter UCKERT
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Patent number: 8575303Abstract: Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.Type: GrantFiled: January 19, 2011Date of Patent: November 5, 2013Assignee: Sirigen Group LimitedInventors: Brent S. Gaylord, Jean M. Wheeler, Glenn P. Bartholomew, Yongchao Liang, Janice W. Hong, William H. Huisman, Frank Peter Uckert, Lan T. Tran, Adrian Charles Vernon Palmer, Trung Nguyen, Russell A. Baldocchi
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Patent number: 8354239Abstract: Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.Type: GrantFiled: August 1, 2011Date of Patent: January 15, 2013Assignee: Sirigen, Inc.Inventors: Brent S. Gaylord, Janice W. Hong, Tsu-Ju Fu, Cheng-Jun Sun, Russell Baldocchi
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Patent number: 8158444Abstract: Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.Type: GrantFiled: October 8, 2007Date of Patent: April 17, 2012Assignee: Sirigen, Inc.Inventors: Brent S. Gaylord, Janice W. Hong, Tsu-Ju Fu, Cheng-Jun Sun, Russell Baldocchi
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Publication number: 20120029155Abstract: Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.Type: ApplicationFiled: August 1, 2011Publication date: February 2, 2012Applicant: SIRIGEN INC.Inventors: Brent S. Gaylord, Janice W. Hong, Tsu-Ju Fu, Cheng-Jun Sun, Russell Baldocchi
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Publication number: 20120028828Abstract: Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.Type: ApplicationFiled: August 1, 2011Publication date: February 2, 2012Applicant: SIRIGEN INC.Inventors: Brent S. Gaylord, Janice W. Hong, Tsu-Ju Fu, Cheng-Jun Sun, Russell Baldocchi
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Publication number: 20110257374Abstract: Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.Type: ApplicationFiled: January 19, 2011Publication date: October 20, 2011Applicant: Sirigen, Inc.Inventors: Brent S. Gaylord, Jean M. Wheeler, Glenn P. Bartholomew, Yongchao Liang, Janice W. Hong, William H. Huisman, Frank Peter Uckert, Lan T. Tran, Adrian Charles Vernon Palmer, Trung Nguyen, Russell A. Baldocchi
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Publication number: 20080293164Abstract: Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.Type: ApplicationFiled: October 8, 2007Publication date: November 27, 2008Inventors: Brent S. Gaylord, Janice W. Hong, Tsu-Ju Fu, Cheng-Jun Sun, Russell Baldocchi
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Patent number: 6465182Abstract: The present invention provides methods of determining relative copy number of target nucleic acid sequences and precise mapping of chromosomal abnormalities associated with disease. The methods of the invention use target nucleic acid sequences immobilized on a solid surface, to which a sample comprising two sets of differentially labeled nucleic acid sequences are hybridized. The hybridization of the labeled nucleic acid sequences to the solid surface is then detected using standard techniques.Type: GrantFiled: April 29, 1999Date of Patent: October 15, 2002Assignee: The Regents of the University of CaliforniaInventors: Joe Gray, Dan Pinkel, Donna Albertson, Colin Collins, Russell Baldocchi