Abstract: A cargo carrier is disclosed for the efficient delivery of cargo to space, such as to support the International Space Station (ISS). Both pressurized and unpressurized cargo may be delivered into space on an expendable launch vehicle, such as the Delta-IV rocket. The cargo carrier may utilize a slightly modified Delta-IV second stage to provide on-orbit station keeping of the payload until it is transferred to the ISS. The cargo carrier can include an unpressurized section having a rigid central structure supporting a frame to which unpressurized cargo modules are coupled. In addition, a pressurized cargo section may be coupled to the unpressurized section. The cargo carrier may utilize existing on-orbit assets such as the European Automated Transfer Vehicle (ATV) to transfer the ISS cargo from a rendezvous orbit to the ISS.