Patents by Inventor Russell C. Addis

Russell C. Addis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240043844
    Abstract: The present disclosure relates to compositions, such as siRNA molecules and FN3 domains conjugated to the same, in combination with enzyme replacement therapies, as well as methods of making and using the same.
    Type: Application
    Filed: April 14, 2023
    Publication date: February 8, 2024
    Inventors: Swapnil KULKARNI, Russell C. ADDIS, Steven G. NADLER, Yao XIN, Zhanna DRUZINA, Karyn T. O'NEIL, Robert V. KOLAKOWSKI, Stephen J. ANDERSON
  • Publication number: 20230330239
    Abstract: The present disclosure relates to polypeptides, such as fibronectin type III (FN3) domains that can bind EpCAM, their conjugates, isolated nucleotides encoding the molecules, vectors, host-cells, as well as methods of making and using the molecules.
    Type: Application
    Filed: October 14, 2020
    Publication date: October 19, 2023
    Inventors: Russell C. ADDIS, Robert KOLAKOWSKI, Swapnil KULKARNI, Steven G. NADLER, Karyn O'NEIL, Yao XIN
  • Patent number: 11781138
    Abstract: The present disclosure relates to compositions, such as siRNA molecules and FN3 domains conjugated to the same, as well as methods of making and using the molecules.
    Type: Grant
    Filed: October 14, 2020
    Date of Patent: October 10, 2023
    Assignee: Aro Biotherapeutics Company
    Inventors: Russell C. Addis, Zhanna Druzina, Robert Kolakowski, Swapnil Kulkarni, Steven G. Nadler, Karyn O'Neil, Yao Xin
  • Patent number: 11628222
    Abstract: The present disclosure relates to polypeptides, such as fibronectin type III (FN3) domains that can bind CD71, their conjugates, isolated nucleotides encoding the molecules, vectors, host-cells, as well as methods of making and using the same.
    Type: Grant
    Filed: October 14, 2020
    Date of Patent: April 18, 2023
    Assignee: ARO BIOTHERAPEUTICS COMPANY
    Inventors: Russell C. Addis, Zhanna Druzina, Robert Kolakowski, Swapnil Kulkarni, Steven G. Nadler, Karyn O'Neil, Yao Xin
  • Publication number: 20230039851
    Abstract: Fibronectin type III domains (FN3) that bind to serum albumin, related polynucleotides capable of encoding serum albumin-binding FN3 domains, cells expressing the FN3 domains, as well as associated vectors, detectably labeled FN3 domains and FN3 domains fused to a heterologous moiety are useful in extending the half-life of molecules in diagnostic and therapeutic applications.
    Type: Application
    Filed: December 18, 2020
    Publication date: February 9, 2023
    Inventors: Karyn O'NEIL, Yao XIN, Russell C. ADDIS
  • Publication number: 20220370626
    Abstract: The present disclosure relates to compositions, such as siRNA molecules and FN3 domains conjugated to the same, as well as methods of making and using the molecules.
    Type: Application
    Filed: April 14, 2022
    Publication date: November 24, 2022
    Inventors: Swapnil KULKARNI, Russell C. ADDIS, Steven G. NADLER, Yao XIN, Zhanna DRUZINA, Karyn T. O'NEIL, Robert V. KOLAKOWSKI, Stephen J. ANDERSON
  • Publication number: 20220332795
    Abstract: The present disclosure relates to polypeptides, such as fibronectin type III (FN3) domains that can bind CD71, their conjugates, isolated nucleotides encoding the molecules, vectors, host-cells, as well as methods of making and using the same.
    Type: Application
    Filed: April 14, 2022
    Publication date: October 20, 2022
    Inventors: Russell C. ADDIS, Zhanna DRUZINA, Robert V. KOLAKOWSKI, Steven G. NADLER, Karyn T. O'NEIL, Yao XIN
  • Publication number: 20210145976
    Abstract: The present disclosure relates to polypeptides, such as fibronectin type III (FN3) domains that can bind CD71, their conjugates, isolated nucleotides encoding the molecules, vectors, host-cells, as well as methods of making and using the same.
    Type: Application
    Filed: October 14, 2020
    Publication date: May 20, 2021
    Inventors: Russell C. Addis, Zhanna Druzina, Robert Kolakowski, Swapnil Kulkarni, Steven G. Nadler, Karyn O'Neil, Yao Xin
  • Publication number: 20210108201
    Abstract: The present disclosure relates to compositions, such as siRNA molecules and FN3 domains conjugated to the same, as well as methods of making and using the molecules.
    Type: Application
    Filed: October 14, 2020
    Publication date: April 15, 2021
    Inventors: Russell C. Addis, Zhanna Druzina, Robert Kolakowski, Swapnil Kulkarni, Steven G. Nadler, Karyn O'Neil, Yao Xin