Abstract: In a threat management platform, a number of endpoints log events in an event data recorder. A local agent filters this data and feeds a filtered data stream to a central threat management facility. The central threat management facility can locally or globally tune filtering by local agents based on the current data stream, and can query local event data recorders for additional information where necessary or helpful in threat detection or forensic analysis. The central threat management facility also stores and deploys a number of security tools such as a web-based user interface supported by machine learning models to identify potential threats requiring human intervention and other models to provide human-readable context for evaluating potential threats.

Abstract: Provided are photoacoustic imaging contrast agents that include at least one radiation-absorbing component comprising a copper-complexed and/or manganese-complexed chlorin and/or bacteriochlorin and/or a derivative thereof, or a combination thereof. Also provided are methods for using the disclosed photoacoustic imaging contrast agents either singly or in combination for generating an image of a volume, optionally a subject or a body part, cell, tissue, or organ thereof. Further provided are compositions and methods for multiplex photoacoustic imaging of a volume, optionally a subject or a body part, cell, tissue, or organ thereof using photoacoustic imaging contrast agents that include a plurality of the presently disclosed copper-complexed and/or manganese-complexed chlorins and/or bacteriochlorins and/or derivatives thereof simultaneously.

Abstract: Provided are photoacoustic imaging contrast agents that include at least one radiation-absorbing component comprising a copper-complexed and/or manganese-complexed chlorin and/or bacteriochlorin and/or a derivative thereof, or a combination thereof. Also provided are methods for using the disclosed photoacoustic imaging contrast agents either singly or in combination for generating an image of a volume, optionally a subject or a body part, cell, tissue, or organ thereof. Further provided are compositions and methods for multiplex photoacoustic imaging of a volume, optionally a subject or a body part, cell, tissue, or organ thereof using photoacoustic imaging contrast agents that include a plurality of the presently disclosed copper-complexed and/or manganese-complexed chlorins and/or bacteriochlorins and/or derivatives thereof simultaneously.

Abstract: Provided are photoacoustic imaging contrast agents that include at least one radiation-absorbing component comprising a copper-complexed and/or manganese-complexed chlorin and/or bacteriochlorin and/or a derivative thereof, or a combination thereof. Also provided are methods for using the disclosed photoacoustic imaging contrast agents either singly or in combination for generating an image of a volume, optionally a subject or a body part, cell, tissue, or organ thereof. Further provided are compositions and methods for multiplex photoacoustic imaging of a volume, optionally a subject or a body part, cell, tissue, or organ thereof using photoacoustic imaging contrast agents that include a plurality of the presently disclosed copper-complexed and/or manganese-complexed chlorins and/or bacteriochlorins and/or derivatives thereof simultaneously.

Abstract: Provided are photoacoustic imaging contrast agents that include at least one radiation-absorbing component comprising a bacteriochlorin, a metallobacteriochlorin, a derivative thereof, or a combination thereof. Also provided are methods for using the disclosed photoacoustic imaging contrast agents either singly or in combination for generating an image of a volume, optionally a subject or a body part, cell, tissue, or organ thereof. Further provided are compositions and methods for multiplex photoacoustic imaging of a volume, optionally a subject or a body part, cell, tissue, or organ thereof using photoacoustic imaging contrast agents that include a plurality of the presently disclosed bacteriochlorins, metallobacteriochlorins, and/or derivatives thereof simultaneously.

Abstract: A GPS receiver (26) for processing GPS satellite signals and adapted for connection to a client device (24). The receiver (26) includes a down converter (44), a correlator (46), and a microcomputer A. The microcomputer A has a microprocessor A, a first memory (48A), a second memory (48B, 148B), and an input/output interface (50). The input/output interface (50) is capable of being connected to the client device (24). The first memory (48A) contains a first set of instructions for the microprocessor A to download and store in the second memory (48B, 148B) at least one time critical GPS software module (A1, A2, . . . AN) from the client device (24). The first memory (48A) also contains a second set of instructions for the microprocessor A to determine whether to download and store in the second memory (48B, 148B) a plurality of non-time critical software modules (B1, B2, . . . BN) from the client device (24).

Abstract: A method of determining a reference frequency in a wireless communication device is disclosed. The method comprises the steps of providing a known frequency source; receiving a signal from an unknown frequency source; and calculating an estimate of the frequency of the signal from the unknown frequency source based upon the frequency of the known frequency source. establishing a communication link based upon the frequency of the signal from the unknown frequency source. A wireless communication device according to the present invention is also disclosed comprising a first frequency source associated with a GPS receiver and generating a substantially fixed frequency; a second frequency source associated with a host device and generating an unknown frequency; a counter coupled to the second frequency source; and a control circuit coupled to the counter, the control circuit determining the frequency of the second frequency source based upon the substantially fixed frequency and a value of the counter.

Abstract: An apparatus for post-correlation signal processing includes a plurality of correlators for correlating a received signal with a predetermined signal to produce a plurality of correlator output signals and a selection circuit coupled to the plurality of correlators for selecting a correlator output signal from one of the plurality of correlator output signals to provide a selected correlator output signal. A memory is coupled to the selection circuit for storing post correlation totals. A counter is coupled to the memory for synchronizing the memory with the predetermined signal. An adder is coupled to the memory and to the selection circuit for combining the selected correlator output signal with the post correlation total from the memory to form a new post correlation total. The memory replaces the previous post correlation total with the new post correlation total.

Abstract: A symbol state trellis maximum likelihood detection method greatly limits the number of possible interfering symbols which require examination. This method has considerable processing advantages over other optimal maximum likelihood detection methods. For practical configurations, the symbol state trellis maximum likelihood detection method provides a performance which is less than 1 dB from the optimal maximum likelihood detection method while simultaneously providing for a similar bit error rate. The symbol state trellis maximum likelihood detection method calculates the phase errors for all paths from a present state to a previous state. Next, total path distances are calculated for previously selected paths to the previous state. The phase error associated with each of the paths from two states previous to the present state are calculated. For each symbol of the present state, only one path is selected to each symbol. This path corresponds to the path with the minimum phase error.