Abstract: A fluid fillable cushioning device comprises an enclosure comprising a top wall and a bottom wall, a cavity defined by the enclosure, a threaded inlet in the enclosure connected to the cavity, the cavity further defined by the threaded inlet, and a fastening mechanism extending from the enclosure, the fastening mechanism configured to fasten the cushioning device to a seat. In operation, fluid, such as water, is filled in the cavity of the cushioning device, and in some cases foam is also included in the cavity, providing a water and/or foam cushion for a user sitting on the cushioning device. When used on seat of a bicycle, where the user's body interacts with the cushioning device with significant pressure for extended period of time, the cushioning device provides customizable cushioning which feels like an extension of the body, and is exceptionally comfortable.

Abstract: A protective casing is for a receiving and protecting a manifold gauge assembly having a gauge and a hose. The protective casing has a base member with a first end and an opposite, second end and a pair of opposing side members extending from the base member in a first direction such that the base member and the side members define a cavity. The side members define a channel through which the hose passes into a cavity such that hose is received in the cavity and the gauge is positioned at the first end.

Abstract: A protective casing is for a receiving and protecting a manifold gauge assembly having a gauge and a hose. The protective casing has a base member with a first end and an opposite, second end and a pair of opposing side members extending from the base member in a first direction such that the base member and the side members define a cavity. The side members define a channel through which the hose passes into a cavity such that hose is received in the cavity and the gauge is positioned at the first end.

Abstract: A stereoscopic viewing apparatus comprises a left eyepiece corresponding to a left light path for viewing by a left eye, and right eyepiece corresponding to a right eye path for viewing by a right eye. At least one light-shifting device is positioned in at least one of the left light path or the right light path, wherein the at least one light-shifting device displaces light incident on at least one of the left eye or the right eye, thereby creating a spectacular 3D enhancement when viewing very distant objects.

Abstract: In one aspect, the present invention relates to a formulation in the form of molecular dispersion comprising i) fenofibric acid, a physiologically acceptable salt or derivative thereof and optionally other active substances, ii) a binder component comprising at least one enteric binder, and optionally iii) other physiologically acceptable excipients. In a second aspect, the present invention relates to novel salts of fenofibric acid that are photostable when compared to other salts of fenofibric acid.

Abstract: In one aspect, the present invention relates to a formulation in the form of molecular dispersion comprising i) fenofibric acid, a physiologically acceptable salt or derivative thereof and optionally other active substances, ii) a binder component comprising at least one enteric binder, and optionally iii) other physiologically acceptable excipients. In a second aspect, the present invention relates to novel salts of fenofibric acid that are photostable when compared to other salts of fenofibric acid.

Abstract: There is provided a hemihydrate of (3?,5?,7?,12?)-7,12-dihydroxy-3-{2-[{4-[17?-hydroxy-3-oxo-17?-prop-1-ynylestra-4,9-dien-11?-yl]phenyl}(methyl)amino]ethoxy}cholan-24-oic acid in a crystalline form which is characterised by an X-ray diffraction pattern having major peaks at 2?=6.58±0.2, 8.54+0.2, 12.28±0.2, and 19.68±0.2. This crystalline material is useful in the treatment of conditions associated with an excess of hepatic glucocorticoid response.

Abstract: There is provided a hemihydrate of (3?, 5?, 7?, 12?)-7,12-dihydroxy-3-{2-[{4-[17?-hydroxy-3-oxo-17?-prop-1-ynylestra-4,9-dien-11?-yl]phenyl}(methyl)amino]ethoxy}cholan-24-oic acid in a crystalline form which is characterised by an X-ray diffraction pattern having major peaks at 2?=6.58±0.2, 8.54+0.2, 12.28±0.2, and 19.68±0.2. This crystalline material is useful in the treatment of conditions associated with an excess of hepatic glucocorticoid response.

Abstract: This invention relates to novel compounds that are liver selective glucocorticoid receptor antagonists, to methods of preparing such compounds, and to methods for using such compounds in the regulation of metabolism, especially lowering serum glucose levels, insulin levels, or lipid levels, and/or decreasing body weight.

Abstract: In one aspect, the present invention relates to a formulation in the form of molecular dispersion comprising i) fenofibric acid, a physiologically acceptable salt or derivative thereof and optionally other active substances, ii) a binder component comprising at least one enteric binder, and optionally iii) other physiologically acceptable excipients. In a second aspect, the present invention relates to novel salts of fenofibric acid that are photostable when compared to other salts of fenofibric acid.

Abstract: An optical corrector system optical system comprising two components, a first housing supporting therein a telenegative-type lens, and a second housing supporting therein a positive-type lens. The first housing is adapted to be coupled to a telescope in a manner so that the telenegative lens intercepts the image plane provided by the telescope. The second housing is adapted to be coupled to an image input portion of a remote viewing device. Opposite ends of the first and second housings are adapted to be coupled to each other in a manner so that the distance between the telenegative lens in the first housing and the positive lens in the second housing results in the intercepted image plane being repositioned from a viewing position at the telescope, to a viewing position at the remote viewing device. In a preferred embodiment, the remote viewing device comprises a binocular viewer.

Abstract: This invention relates to novel compounds that are liver selective glucocorticoid receptor antagonists, to methods of preparing such compounds, and to methods for using such compounds in the regulation of metabolism, especially lowering serum glucose levels, insulin levels, or lipid levels, and/or decreasing body weight.

Abstract: This invention relates to novel compounds that are liver selective glucocorticoid receptor antagonists, to methods of preparing such compounds, and to methods for using such compounds in the regulation of metabolism, especially lowering serum glucose levels, insulin levels, or lipid levels, and/or decreasing body weight.

Abstract: Synthetic Phorboxazole A and derivatives thereof for the treatment of cancer, including inhibition of cancer cell growth, induction of apoptosis, and inhibition of metastises.

Abstract: An optical corrector system optical system comprising two components, a first housing supporting therein a telenegative-type lens, and a second housing supporting therein a positive-type lens. The first housing is adapted to be coupled to a telescope in a manner so that the telenegative lens intercepts the image plane provided by the telescope. The second housing is adapted to be coupled to an image input portion of a remote viewing device. Opposite ends of the first and second housings are adapted to be coupled to each other in a manner so that the distance between the telenegative lens in the first housing and the positive lens in the second housing results in the intercepted image plane being repositioned from a viewing position at the telescope, to a viewing position at the remote viewing device. In a preferred embodiment, the remote viewing device comprises a binocular viewer.