Patents by Inventor Russell Ernst

Russell Ernst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CELLS, TISSUES, ORGANS, AND ANIMALS HAVING ONE OR MORE MODIFIED GENES FOR ENHANCED XENOGRAFT SURVIVAL AND TOLERANCE
    Publication number: 20240084322
    Abstract: The present disclosure relates to cells, tissues, organs, and/or animals having one or more modified genes for enhanced xenograft survival and/or tolerance. In addition, the present disclosure relates to methods of making and using the cells, tissues, organs, and/or animals having one or more of the modified genes.
    Type: Application
    Filed: June 1, 2023
    Publication date: March 14, 2024
    Inventors: Jacob LAYER, Wenning QIN, Yinan KAN, Juliet CRABTREE, Michele YOUD, David HEJA, David ANGELES ALBORES, Ranjith ANAND, Paola PERRAT, Russell ERNST, Violette PARAGAS
  • Metalloinsertor complexes targeted to DNA mismatches
    Patent number: 9051345
    Abstract: A composition including a Rh or Ru metalloinsertor complex specifically targets mismatch repair (MMR)-deficient cells. Selective cytotoxicity is induced in MMR-deficient cells upon uptake of the inventive metalloinsertor complexes.
    Type: Grant
    Filed: June 13, 2013
    Date of Patent: June 9, 2015
    Assignee: California Institute of Technology
    Inventors: Jacqueline K. Barton, Alexis Komor, Curtis J. Schneider, Alyson Weidmann, Russell Ernst
  • Metalloinsertor complexes targeted to DNA mismatches
    Patent number: 8859533
    Abstract: A composition including a Rh or Ru metalloinsertor complex specifically targets mismatch repair (MMR)-deficient cells. Selective cytotoxicity is induced in MMR-deficient cells upon uptake of the inventive metalloinsertor complexes.
    Type: Grant
    Filed: May 10, 2012
    Date of Patent: October 14, 2014
    Assignee: California Institute of Technology
    Inventors: Jacqueline K. Barton, Alexis Komor, Curtis J. Schneider, Alyson Weidmann, Russell Ernst
  • METALLOINSERTOR COMPLEXES TARGETED TO DNA MISMATCHES
    Publication number: 20130345189
    Abstract: A composition including a Rh or Ru metalloinsertor complex specifically targets mismatch repair (MMR)-deficient cells. Selective cytotoxicity is induced in MMR-deficient cells upon uptake of the inventive metalloinsertor complexes.
    Type: Application
    Filed: June 13, 2013
    Publication date: December 26, 2013
    Inventors: Jacqueline K. Barton, Alexis Komor, Curtis J. Schneider, Alyson Weidmann, Russell Ernst
  • METALLOINSERTOR COMPLEXES TARGETED TO DNA MISMATCHES
    Publication number: 20130090319
    Abstract: A composition including a Rh or Ru metalloinsertor complex specifically targets mismatch repair (MMR)-deficient cells. Selective cytotoxicity is induced in MMR-deficient cells upon uptake of the inventive metalloinsertor complexes.
    Type: Application
    Filed: May 10, 2012
    Publication date: April 11, 2013
    Inventors: Jacqueline K. Barton, Alexis Komor, Curtis J. Schneider, Alyson Weidmann, Russell Ernst
  • NETWORK TRANSACTION DISCOVERY
    Publication number: 20110264801
    Abstract: Disclosed herein is a computer implemented technique for discovering the information technology resources that are involved in a particular networked business transaction. The system comprises three basic components. A robotic transaction playback client records the various steps in a particular transaction and can repetitively execute these steps to analyze the results. A network record collector observes the traffic throughout the network in response to the repeated instances of the transaction executed by the robotic transaction playback client. A backend processor analyzes the observations of network traffic to determine which ones are possibly tied to the transaction, and from this information determine which network components are part of the transaction being analyzed. Event timing information from a plurality of executions of a particular transaction are used to determine resource usage and paths.
    Type: Application
    Filed: June 30, 2011
    Publication date: October 27, 2011
    Inventor: Theodore Russell Ernst
  • Network transaction discovery
    Patent number: 7996515
    Abstract: Disclosed herein is a computer implemented technique for discovering the information technology resources that are involved in a particular networked business transaction. The system comprises three basic components. A robotic transaction playback client records the various steps in a particular transaction and can repetitively execute these steps to analyze the results. A network record collector observes the traffic throughout the network in response to the repeated instances of the transaction executed by the robotic transaction playback client. A backend processor analyzes the observations of network traffic to determine which ones are possibly tied to the transaction, and from this information determine which network components are part of the transaction being analyzed. Event timing information from a plurality of executions of a particular transaction are used to determine resource usage and paths.
    Type: Grant
    Filed: June 15, 2005
    Date of Patent: August 9, 2011
    Assignee: BMC Software, Inc.
    Inventor: Theodore Russell Ernst