Patents by Inventor Russell H. Neubauer

Russell H. Neubauer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-quinoline carboxylic acid derivatives useful as immunosuppressive agents
    Patent number: 5084462
    Abstract: 4-Quinolinecarboxylic acids and derivatives thereof, such as 2-(2'-fluoro-1,1'-biphenyl-4-yl)-6-fluoro-3-methyl-4-quinolinecarboxylic acid, are useful as immunodulatory and anti-inflammatory agents. Pharmaceutical formulations containing such compounds are useful for the treatment of autoimmune diseases, organ transplantation rejection, graft vs. host disease, multiple sclerosis, and chronic inflammatory diseases such as rheumatoid arthritis.
    Type: Grant
    Filed: June 28, 1990
    Date of Patent: January 28, 1992
    Assignee: The Du Pont Merck Pharmaceutical Company
    Inventors: Neil R. Ackerman, Bruce D. Jaffee, Scott E. Loveless, Russell H. Neubauer
  • Stable human cell lines expressing an indicator gene product under virus-specific genetic controls
    Patent number: 5026635
    Abstract: The invention relates to stable mammalian cells lines having integrated in their genome two heterologous DNA sequences, a first DNA sequence which expresses a trans-acting regulatory protein, and a second DNA sequence which expresses a desired protein, said second DNA sequence being linked to a target DNA regulatory control sequence which is responsive to the expressed trans-acting regulatory protein.
    Type: Grant
    Filed: April 26, 1990
    Date of Patent: June 25, 1991
    Assignee: Du Pont Merck Pharmaceutical
    Inventors: Blair Q. Ferguson, Lee T. Bacheler, Stephen R. Petteway, Russell H. Neubauer
  • 4-Quinoline carboxylic acid derivatives useful as immunosuppressive agents
    Patent number: 4968701
    Abstract: 4-Quinolinecarboxylic acids and derivatives thereof, such as 2-(2'-fluoro-1,1'-biphenyl-4-yl)-6-fluoro-3-methyl-4-quinolinecarboxylic acid, are useful as immunomodulatory and anti-inflammatory agents. Pharmaceutical formulations containing such compounds are useful for the treatment of autoimmune diseases, organ transplantation rejection, graft vs. host disease, multiple sclerosis, and chronic inflammatory diseases such as rheumatoid arthritis.
    Type: Grant
    Filed: April 26, 1988
    Date of Patent: November 6, 1990
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Neil R. Ackerman, Richard R. Harris, Scott E. Loveless, Russell H. Neubauer
  • Test methods employing monoclonal antibodies against Herpes simplex virus types 1 and 2 nucleocapsids proteins
    Patent number: 4430437
    Abstract: The method of producing clinical assays for use of monoclonal antibodies in the diagnosis of Herpes simplex virus (HSV) infections and the differentiation of Herpes Simplex virus types 1 and 2 as a diagnostic kit for differentiating HSV-1 and HSV-2 utilizing clone 1D4 against HSV-1 and clone 3E1 against HSV-2.
    Type: Grant
    Filed: August 27, 1980
    Date of Patent: February 7, 1984
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Berge Hampar, Martin Zweig, Harvey Rabin, Conrad J. Heilman, Jr., Ralph F. Hopkins, III, Russell H. Neubauer