Patents by Inventor Russell L. Dedrick

Russell L. Dedrick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for diagnosing and monitoring the status of systemic lupus erythematosus
    Patent number: 8148067
    Abstract: The invention presents a method of diagnosing or monitoring the status of systemic lupus erythematosus (SLE) in a subject or patient comprising detecting the expression of all genes of a diagnostic set in the subject or patient wherein the diagnostic set comprises two or more genes having expression correlated with the classification or status of SLE; and diagnosing or monitoring the status of SLE in the subject or patient by applying at least one statistical method to the expression of the genes of the diagnostic set.
    Type: Grant
    Filed: November 9, 2007
    Date of Patent: April 3, 2012
    Assignee: Xdx, Inc.
    Inventors: Preeti G. Lal, Gavin E. Williams, Kirk E. Fry, Jingtao Sun, Russell L. Dedrick
  • Methods and compositions for diagnosing and monitoring the status of transplant rejection and immune disorders
    Patent number: 7993832
    Abstract: The invention presents methods of using splice variants and reagents thereof for diagnosing and monitoring the status of transplants and immune disorders including diagnosing, monitoring and predicting transplant rejection or non-rejection, steroid responsiveness, and onset or flare of immune disorders.
    Type: Grant
    Filed: August 14, 2007
    Date of Patent: August 9, 2011
    Assignee: XDx, Inc.
    Inventors: Steven Rosenberg, Kirk Fry, Bin Wu, Russell L. Dedrick
  • METHODS FOR DIAGNOSING AND MONITORING THE STATUS OF SYSTEMIC LUPUS ERYTHEMATOSUS
    Publication number: 20090298060
    Abstract: The invention presents a method of diagnosing or monitoring the status of systemic lupus erythematosus (SLE) in a subject or patient comprising detecting the expression of all genes of a diagnostic set in the subject or patient wherein the diagnostic set comprises two or more genes having expression correlated with the classification or status of SLE; and diagnosing or monitoring the status of SLE in the subject or patient by applying at least one statistical method to the expression of the genes of the diagnostic set.
    Type: Application
    Filed: November 9, 2007
    Publication date: December 3, 2009
    Applicant: XDX, Inc.
    Inventors: Preeti G. LAL, Gavin E. Williams, Kirk E. Fry, Jingtao Sun, Russell L. Dedrick
  • Treatment of LFA-1 associated disorders with increasing doses of LFA-1 antagonist
    Patent number: 7364734
    Abstract: A method is provided for reducing the occurrence of fever, headache, nausea and/or vomiting associated with administration of a therapeutic compound to a mammal in need thereof, comprising administering to the mammal a first conditioning dose of a non-target cell depleting compound which binds to a cell surface receptor on a target mammalian cell; and administering a second therapeutic dose of the compound, wherein the second dose is higher than the first dose.
    Type: Grant
    Filed: March 10, 2005
    Date of Patent: April 29, 2008
    Assignee: Genentech, Inc.
    Inventors: Marvin R. Garovoy, Susan M. Kramer, Russell L. Dedrick, Karen Starko
  • Treatment of LFA-1 associated disorders with increasing doses
    Publication number: 20040047859
    Abstract: A method is provided for reducing the occurrence of fever, headache, nausea and/or vomiting associated with administration of a therapeutic compound to a mammal in need thereof, comprising administering to the mammal a first conditioning dose of a non-target cell depleting compound which binds to a cell surface receptor on a target mammalian cell; and administering a second therapeutic dose of the compound, wherein the second dose is higher than the first dose.
    Type: Application
    Filed: September 5, 2003
    Publication date: March 11, 2004
    Applicants: Genentech, Inc., Xoma Ltd.
    Inventors: Marvin R. Garovoy, Susan M. Kramer, Russell L. Dedrick, Karen Starko
  • Uses of lipopolysaccharide binding protein
    Publication number: 20030236187
    Abstract: Novel LBP compositions and therapeutic uses for LBP are provided for preventing the adverse effects of exposure to endotoxin.
    Type: Application
    Filed: October 23, 2001
    Publication date: December 25, 2003
    Applicant: XOMA Corporation
    Inventors: Russell L. Dedrick, Stephen F. Carroll
  • Treatment method
    Publication number: 20030223988
    Abstract: A method is provided for reducing the occurrence of fever, headache, nausea and/or vomiting associated with administration of a therapeutic compound to a mammal in need thereof, comprising administering to the mammal a first conditioning dose of a non-target cell depleting compound which binds to a cell surface receptor on a target mammalian cell; and administering a second therapeutic dose of the compound, wherein the second dose is higher than the first dose.
    Type: Application
    Filed: June 20, 2003
    Publication date: December 4, 2003
    Applicants: Genentech, Inc., Xoma Technology, Ltd.
    Inventors: Russell L. Dedrick, Marvin R. Garovoy, Susan M. Kramer, Karen M. Starko
  • Treatment of LFA-1 associated disorders with increasing doses of LFA-1 antagonist
    Patent number: 6652855
    Abstract: A method is provided for reducing the occurrence of fever, headache, nausea and/or vomiting associated with administration of a therapeutic compound to a mammal in need therof, comprising administering to the mammal a first conditioning dose of a non-target cell depleting compound which binds to a cell surface receptor on a target mammalian cell; and administering a second therapeutic dose of the compound, wherein the second dose is higher than the first dose.
    Type: Grant
    Filed: February 11, 2002
    Date of Patent: November 25, 2003
    Assignees: Genentech, Inc., XOMA Ltd.
    Inventors: Marvin R. Garovoy, Susan M. Kramer, Russell L. Dedrick, Karen Starko
  • Treatment method
    Patent number: 6582698
    Abstract: A method is provided for reducing the occurrence of fever, headache, nausea and/or vomiting associated with administration of a therapeutic compound to a mammal in need thereof, comprising administering to the mammal a first conditioning dose of a non-target cell depleting compound which binds to a cell surface receptor on a target mammalian cell; and administering a second therapeutic dose of the compound, wherein the second dose is higher than the first dose.
    Type: Grant
    Filed: March 28, 2001
    Date of Patent: June 24, 2003
    Assignees: Genentech, Inc., XOMA Technology, Ltd.
    Inventors: Russell L. Dedrick, Marvin R. Garovoy, Susan M. Kramer, Karen M. Starko
  • Uses of lipopolysaccharide binding protein
    Publication number: 20020119930
    Abstract: Novel LBP compositions and therapeutic uses for LBP are provided for preventing the adverse effects of exposure to endotoxin.
    Type: Application
    Filed: October 23, 2001
    Publication date: August 29, 2002
    Applicant: XOMA Corporation
    Inventors: Russell L. Dedrick, Stephen F. Carroll
  • Uses of lipopolysaccharide binding protein
    Patent number: 6306824
    Abstract: Novel LBP compositions and therapeutic uses for LBP are provided for preventing the adverse effects of exposure to endotoxin.
    Type: Grant
    Filed: September 14, 1999
    Date of Patent: October 23, 2001
    Assignee: Xoma Corporation
    Inventors: Russell L. Dedrick, Stephen F. Carroll
  • Uses of lipopolysaccharide binding protein
    Patent number: 5990082
    Abstract: Novel LBP compositions and therapeutic uses for LBP are provided for preventing the adverse effects of exposure to endotoxin.
    Type: Grant
    Filed: October 22, 1997
    Date of Patent: November 23, 1999
    Assignee: Xoma Corporation
    Inventors: Russell L. Dedrick, Stephen F. Carroll