Abstract: The present invention relates to cyclotides and cyclotide-encoding genes from the Fabaceae plant family, and to the expression of cyclotides in Fabaceae. The present invention further relates to isolated nucleic acids configured to express cyclotides comprising heterologous peptide grafts in plants of the Fabaceae family.

Abstract: The present invention relates to cyclotides and cyclotide-encoding genes from the Fabaceae plant family, and to the expression of cyclotides in Fabaceae. The present invention further relates to isolated nucleic acids configured to express cyclotides comprising heterologous peptide grafts in plants of the Fabaceae family.

Abstract: The masts of a front-end loader are releasably attached to vertical plates of a loader mounting frame located at the opposite sides of a tractor by latch hooks pivotally mounted to the masts and engaged with latching elements carried by the vertical plates. An over center biasing arrangement acts on each latch hook and acts to bias the latch hook to a closed position, but moves over center when the latch is manually opened so as to bias the latch to its open position. The pins pivotally coupling the latches to the masts also serve to couple the piston rods of a pair of loader boom lift cylinders to the masts. Extension of the cylinders during detaching the masts from the vertical plates causes the opened latch hooks to be pivoted to the extent that the biasing elements move over center and reset the latches to their closed positions, which positions are conducive for automatically reattaching the mast to the vertical plates.

Abstract: This invention relates uses of components of plant-like metabolic pathways not including psbA or PPi phosphofructokinase and not generally operative in animals or encoded by the plastid DNA, to develop compositions that interfere with Apicomplexan growth and survival. Components of the pathways include enzymes, transit peptides and nucleotide sequences encoding the enzymes and peptides, or promoters of these nucleotide sequences to which antibodies, antisense molecules and other inhibitors are directed. Diagnostic and therapeutic reagents and vaccines are developed based on the components and their inhibitors.

Abstract: This invention relates uses of Toxoplasma gondii chorismate synthase, a component components of plant-like metabolic pathways not including psbA or PPi phosphofructokinase and not generally operative in animals or encoded by the plastid DNA, in assays to develop compositions that interfere with Apicomplexan growth and survival. Components of the pathways include enzymes, transit peptides and nucleotide sequences encoding the enzymes and peptides, or promoters of these nucleotide sequences to which antibodies, antisense molecules and other inhibitors are directed. Diagnostic and therapeutic reagents and vaccines are developed based on T. gondii chorismate synthase and its inhibitors.

Abstract: A sleeve with pre-applied handle for a setup box or a folding carton, wherein the sleeve is formed to match a cross-sectional dimension of the box or carton and be slipped on in close frictional engagement therewith. The sleeve comprises a pair of side walls and top and bottom walls hingedly connected by fold lines to form a tubular structure which is collapsible about the fold lines. A handle is provided in the top wall. The top wall is formed of two panels, one extending from each of the side walls and the panels overlying each other. The handle is secured to the upper surface of the lower of the two panels forming the top wall and extends through a slot in the upper of the two panels forming the top wall. The ends of the handle are secured between the two panels and are further adhesively secured by a sheet having openings through which the ends of the handle may extend into engagement with the upper surface of said lower panel of said top wall to further ensure securement.