Patents by Inventor Russell Philip Grant

Russell Philip Grant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230393124
    Abstract: In certain aspects, disclosed are methods and systems for detecting SARS-CoV-2 analytes in dried samples, as for example, dried blood spots. For example, disclosed are methods for measuring an antibody to SARS-CoV-2 in a dried sample that include the steps of: (a) obtaining a dried sample from a subject; (b) extracting the SARS-COV-2 antibody from the dried sample; and (c) detecting the SARS-COV-2 antibody extracted from the dried sample. In certain embodiments, the method is semi-quantitative. The method may, in certain embodiments, further comprise obtaining measurements from an individual over a period of time to follow the titer of SARS-CoV-2 antibody in the individual. For example, the titer may be followed in the individual for at least 19 weeks or longer.
    Type: Application
    Filed: June 2, 2023
    Publication date: December 7, 2023
    Inventors: Russell Philip Grant, Bradley B. Collier
  • Patent number: 11536733
    Abstract: Disclosed are methods, systems, and computer program products for using liquid chromatography/tandem mass spectrometry (LC-MS/MS) for the analysis of endogenous biomarkers, such as 11-oxo androgens, in a sample. The 11-oxo androgens may comprise at least one of 11-hydroxyandrostendione (11OHA), 11-hydroxytestosterone (11OHT) or 11-ketotestosterone (11KT). More specifically, the methods, systems, and computer program products are described for detecting and quantifying the amount of an 11-oxo-androgen in a sample.
    Type: Grant
    Filed: April 16, 2020
    Date of Patent: December 27, 2022
    Assignee: Laboratory Corporation of America Holdings
    Inventors: Brett Holmquist, Donald Walt Chandler, Russell Philip Grant, William Curtin
  • Patent number: 11442073
    Abstract: Disclosed are methods and systems for measuring serotonin in a sample using liquid chromatography and mass spectrometry.
    Type: Grant
    Filed: November 3, 2020
    Date of Patent: September 13, 2022
    Assignee: Laboratory Corporation of America Holdings
    Inventors: Matthew Lee Francis Crawford, Yvonne Zamorano Wright, Russell Philip Grant
  • Publication number: 20220091131
    Abstract: Disclosed are methods and systems using liquid chromatography/tandem mass spectrometry (LC-MS/MS and 2D-LC-MS/MS) for the proteomic analysis of genotypes. In certain embodiments, samples used in the analysis comprise dried bodily fluids.
    Type: Application
    Filed: November 8, 2021
    Publication date: March 24, 2022
    Applicant: Laboratory Corporation of America Holdings
    Inventors: Christopher Michael Shuford, Russell Philip Grant, Meghan Norris Bradley, Patricia Louise Miller Holland, Michael Levandoski
  • Patent number: 11199547
    Abstract: Disclosed are methods and systems using liquid chromatography/tandem mass spectrometry (LC-MS/MS and 2D-LC-MS/MS) for the proteomic analysis of genotypes. In certain embodiments, samples used in the analysis comprise dried bodily fluids.
    Type: Grant
    Filed: May 31, 2019
    Date of Patent: December 14, 2021
    Assignee: Laboratory Corporation of America Holdings
    Inventors: Christopher Michael Shuford, Russell Philip Grant, Meghan Norris Bradley, Patricia Louise Miller Holland, Michael Levandoski
  • Publication number: 20210246085
    Abstract: Disclosed are methods and systems for the quantification of AngI and/or determination of plasma renin activity in a sample. The methods and systems disclosed herein can be useful for diagnosis of hypertension, aldosteronism and other abnormalities of the renin angiotensin aldosterone system (RAAS).
    Type: Application
    Filed: April 8, 2021
    Publication date: August 12, 2021
    Applicant: Laboratory Corporation of America Holdings
    Inventors: William O. Slade, Jr., Russell Philip Grant, Christopher Michael Shuford
  • Patent number: 11008264
    Abstract: Disclosed are methods and systems for the quantification of AngI and/or determination of plasma renin activity in a sample. The methods and systems disclosed herein can be useful for diagnosis of hypertension, aldosteronism and other abnormalities of the renin angiotensin aldosterone system (RAAS).
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: May 18, 2021
    Assignee: Laboratory Corporation of America Holdings
    Inventors: William O. Slade, Jr., Russell Philip Grant, Christopher Michael Shuford
  • Publication number: 20210062242
    Abstract: Disclosed are methods and systems for the analysis activity of enzyme disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13) in a sample. The methods and systems disclosed herein can be useful for diagnosis of thrombotic thrombocytopenic purpura in a patient.
    Type: Application
    Filed: November 4, 2020
    Publication date: March 4, 2021
    Applicant: Laboratory Corporation of America Holdings
    Inventors: Russell Philip Grant, Christopher Michael Shuford, Meghan Norris Bradley
  • Publication number: 20210048445
    Abstract: Disclosed are methods and systems for measuring serotonin in a sample using liquid chromatography and mass spectrometry.
    Type: Application
    Filed: November 3, 2020
    Publication date: February 18, 2021
    Applicant: Laboratory Corporation of America Holdings
    Inventors: Matthew Lee Francis Crawford, Yvonne Zamorano Wright, Russell Philip Grant
  • Patent number: 10858689
    Abstract: Disclosed are methods and systems for the analysis activity of enzyme disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13) in a sample. The methods and systems disclosed herein can be useful for diagnosis of thrombotic thrombocytopenic purpura in a patient.
    Type: Grant
    Filed: October 11, 2017
    Date of Patent: December 8, 2020
    Assignee: Laboratory Corporation of America Holdings
    Inventors: Russell Philip Grant, Christopher Michael Shuford, Meghan Norris Bradley
  • Patent number: 10859586
    Abstract: Disclosed are methods and systems for measuring serotonin in a sample using liquid chromatography and mass spectrometry.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: December 8, 2020
    Assignee: Laboratory Corporation of America Holdings
    Inventors: Matthew Lee Francis Crawford, Yvonne Zamorano Wright, Russell Philip Grant
  • Publication number: 20200333361
    Abstract: Disclosed are methods, systems, and computer program products for using liquid chromatography/tandem mass spectrometry (LC-MS/MS) for the analysis of endogenous biomarkers, such as 11-oxo androgens, in a sample. The 11-oxo androgens may comprise at least one of 11-hydroxyandrostendione (11OHA), 11-hydroxytestosterone (11OHT) or 11-ketotestosterone (11KT). More specifically, the methods, systems, and computer program products are described for detecting and quantifying the amount of an 11-oxo-androgen in a sample.
    Type: Application
    Filed: April 16, 2020
    Publication date: October 22, 2020
    Inventors: Brett Holmquist, Donald Walt Chandler, Russell Philip Grant, William Curtin
  • Publication number: 20190369116
    Abstract: Disclosed are methods and systems using liquid chromatography/tandem mass spectrometry (LC-MS/MS and 2D-LC-MS/MS) for the proteomic analysis of genotypes. In certain embodiments, samples used in the analysis comprise dried bodily fluids.
    Type: Application
    Filed: May 31, 2019
    Publication date: December 5, 2019
    Inventors: Christopher Michael Shuford, Russell Philip Grant, Meghan Norris Bradley, Patricia Louise Miller Holland, Michael Levandoski
  • Publication number: 20190369113
    Abstract: Disclosed are methods and systems using liquid chromatography/tandem mass spectrometry (LC-MS/MS) for the analysis of endogenous biomarkers isolated from biological samples. In certain embodiments, the samples comprise dried body fluids such as dried plasma.
    Type: Application
    Filed: May 31, 2019
    Publication date: December 5, 2019
    Inventors: Christopher Michael Shuford, Russell Philip Grant, Meghan Norris Bradley, Patricia Louise Miller Holland, Michael Levandoski, Matthew Lee Francis Crawford, Bradley Collier
  • Publication number: 20190331686
    Abstract: The present invention relates to systems and methods for utilizing the measurement of two or more biomarkers to determine a probabilistic assessment for developing ovarian cancer. Particularly, aspects of the present invention are directed to a computer implemented method that includes obtaining, by a computing device, measured levels of two or more biomarkers in a sample obtained from a subject without knowledge of an ovarian mass or tumor in the subject, and determining, by the computing device, a probabilistic assessment of the subject developing ovarian cancer based on the obtained values.
    Type: Application
    Filed: April 25, 2019
    Publication date: October 31, 2019
    Inventors: Stanley Ian Letovsky, Russell Philip Grant, Charles Donald Kafader, II, Christopher Michael Shuford
  • Publication number: 20190120864
    Abstract: Disclosed are methods and systems for measuring serotonin in a sample using liquid chromatography and mass spectrometry.
    Type: Application
    Filed: December 18, 2018
    Publication date: April 25, 2019
    Applicant: Laboratory Corporation of America Holdings
    Inventors: Matthew Lee Francis Crawford, Yvonne Zamorano Wright, Russell Philip Grant
  • Patent number: 10191070
    Abstract: Disclosed are methods and systems for measuring serotonin in a sample using liquid chromatography and mass spectrometry.
    Type: Grant
    Filed: March 3, 2016
    Date of Patent: January 29, 2019
    Assignee: Laboratory Corporation of America Holdings
    Inventors: Matthew Lee Francis Crawford, Yvonne Zamorano Wright, Russell Philip Grant
  • Publication number: 20180163249
    Abstract: Disclosed are methods and systems for the analysis activity of enzyme disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13) in a sample. The methods and systems disclosed herein can be useful for diagnosis of thrombotic thrombocytopenic purpura in a patient.
    Type: Application
    Filed: October 11, 2017
    Publication date: June 14, 2018
    Inventors: Russell Philip Grant, Christopher Michael Shuford, Meghan Norris Bradley
  • Publication number: 20180134634
    Abstract: Disclosed are methods and systems for the quantification of AngI and/or determination of plasma renin activity in a sample. The methods and systems disclosed herein can be useful for diagnosis of hypertension, aldosteronism and other abnormalities of the renin angiotensin aldosterone system (RAAS).
    Type: Application
    Filed: November 17, 2017
    Publication date: May 17, 2018
    Inventors: William O. Slade, Jr., Russell Philip Grant, Christopher Michael Shuford
  • Publication number: 20160258969
    Abstract: Disclosed are methods and systems for measuring serotonin in a sample using liquid chromatography and mass spectrometry.
    Type: Application
    Filed: March 3, 2016
    Publication date: September 8, 2016
    Applicant: Laboratory Corporation of America Holdings
    Inventors: Matthew Lee Francis Crawford, Yvonne Zamorano Wright, Russell Philip Grant