Patents by Inventor Rustem KHAFIZOV

Rustem KHAFIZOV has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHEMICAL COMPOSITIONS AND METHODS OF USING SAME
    Publication number: 20250236907
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Application
    Filed: December 18, 2024
    Publication date: July 24, 2025
    Inventors: Dwayne L. DUNAWAY, Elizabeth A. MANRAO, Joseph M. BEECHEM, Rustem KHAFIZOV, Sanghamithra KORUKONDA, Yi DENG, Dae KIM, Mark GREGORY, Margaret HOANG
  • Chemical compositions and methods of using same
    Patent number: 12281356
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Grant
    Filed: December 21, 2022
    Date of Patent: April 22, 2025
    Assignee: Bruker Spatial Biology, Inc.
    Inventors: Dwayne Dunaway, Elizabeth A. Manrao, Joseph M. Beechem, Rustem Khafizov, Sanghamithra Korukonda, Yi Deng, Dae Kim, Mark Gregory, Margaret Hoang, Matthew Walsh, Gavin Meredith, Mark McElwain, Peter Skene, Cassandra Burke
  • Chemical compositions and methods of using same
    Patent number: 12209275
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Grant
    Filed: March 21, 2022
    Date of Patent: January 28, 2025
    Assignee: Bruker Spatial Biology, Inc.
    Inventors: Dwayne L. Dunaway, Elizabeth A. Manrao, Joseph M. Beechem, Rustem Khafizov, Sanghamithra Korukonda, Yi Deng, Dae Kim, Mark Gregory, Margaret Hoang
  • METHODS AND COMPOSITIONS FOR THE CHARACTERIZATION OF CANCER
    Publication number: 20240309432
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Application
    Filed: May 20, 2024
    Publication date: September 19, 2024
    Inventors: Rustem KHAFIZOV, Dwayne L. DUNAWAY, Mark GREGORY
  • COMPOSITIONS AND METHODS FOR IN SITU SINGLE CELL ANALYSIS USING ENZYMATIC NUCLEIC ACID EXTENSION
    Publication number: 20240279723
    Abstract: The present disclosure is based in part on probes, compositions, methods, and kits for simultaneous, multiplexed spatial detection and quantification of protein and/or nucleic acid expression in a user-defined region of a tissue, user-defined cell, and/or user-defined subcellular structure within a cell.
    Type: Application
    Filed: June 17, 2022
    Publication date: August 22, 2024
    Inventors: Lidan WU, Rustem KHAFIZOV, Evan Paul PERILLO, Dwayne DUNAWAY, Dae KIM, Joseph M. BEECHEM
  • Chemical compositions and methods of using same
    Patent number: 12049666
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Grant
    Filed: September 21, 2023
    Date of Patent: July 30, 2024
    Assignee: Bruker Spatial Biology, Inc.
    Inventors: Dwayne L. Dunaway, Elizabeth A. Manrao, Joseph M. Beechem, Rustem Khafizov, Sanghamithra Korukonda, Yi Deng, Dae Kim, Mark Gregory, Margaret Hoang
  • CHEMICAL COMPOSITIONS AND METHODS OF USING SAME
    Publication number: 20240084361
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Application
    Filed: September 21, 2023
    Publication date: March 14, 2024
    Inventors: Dwayne L. DUNAWAY, Elizabeth A. MANRAO, Joseph M. BEECHEM, Rustem KHAFIZOV, Sanghamithra KORUKONDA, Yi DENG, Dae KIM, Mark GREGORY, Margaret HOANG
  • Chemical compositions and methods of using same
    Patent number: 11821026
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Grant
    Filed: March 7, 2023
    Date of Patent: November 21, 2023
    Assignee: NanoString Technologies, Inc.
    Inventors: Dwayne L. Dunaway, Elizabeth A. Manrao, Joseph M. Beechem, Rustem Khafizov, Sanghamithra Korukonda, Yi Deng, Dae Kim, Mark Gregory, Margaret Hoang
  • CHEMICAL COMPOSITIONS AND METHODS OF USING SAME
    Publication number: 20230257800
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Application
    Filed: March 7, 2023
    Publication date: August 17, 2023
    Inventors: Dwayne L. DUNAWAY, Elizabeth A. Manrao, Joseph M. Beechem, Rustem Khafizov, Sanghamithra Korukonda, Yi Deng, Dae Kim, Mark Gregory, Margaret Hoang
  • COMPOSITIONS AND METHODS FOR IN SITU SINGLE CELL ANALYSIS USING ENZYMATIC NUCLEIC ACID EXTENSION
    Publication number: 20230235384
    Abstract: The present disclosure is based in part on probes, compositions, methods, and kits for simultaneous, multiplexed spatial detection and quantification of protein and/or nucleic acid expression in a user-defined region of a tissue, user-defined cell, and/or user-defined subcellular structure within a cell.
    Type: Application
    Filed: June 17, 2021
    Publication date: July 27, 2023
    Inventors: Jonathan CHENG, Dwayne DUNAWAY, Mark GREGORY, Jaemyeong JUNG, Rustem KHAFIZOV, Dae KIM, Evan Paul PERILLO, Tushar RANE, Lidan WU
  • CHEMICAL COMPOSITIONS AND METHODS OF USING SAME
    Publication number: 20230220461
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Application
    Filed: December 21, 2022
    Publication date: July 13, 2023
    Inventors: Dwayne DUNAWAY, Elizabeth A. MANRAO, Joseph M. BEECHEM, Rustem KHAFIZOV, Sanghamithra KORUKONDA, Yi DENG, Dae KIM, Mark GREGORY, Margaret HOANG, Matthew WALSH, Gavin MEREDITH, Mark MCELWAIN, Peter SKENE, Cassandra Burke
  • CHEMICAL COMPOSITIONS AND METHODS OF USE
    Publication number: 20230183800
    Abstract: The present invention relates to sequencing probes, methods, kits, and apparatuses that provide enzyme-free, amplification-free, and library-free nucleic acid sequencing that has long-read-lengths and with low error rate.
    Type: Application
    Filed: February 22, 2023
    Publication date: June 15, 2023
    Inventors: Joseph M. BEECHEM, Rustem KHAFIZOV
  • CHEMICAL COMPOSITIONS AND METHODS OF USE
    Publication number: 20230160004
    Abstract: The present invention relates to sequencing probes, methods, kits, and apparatuses that provide enzyme-free, amplification-free, and library-free nucleic acid sequencing that has long-read-lengths and with low error rate.
    Type: Application
    Filed: July 29, 2022
    Publication date: May 25, 2023
    Inventors: Joseph M. BEECHEM, Rustem KHAFIZOV
  • Chemical compositions and methods of using same
    Patent number: 11549139
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Grant
    Filed: May 14, 2019
    Date of Patent: January 10, 2023
    Assignee: NanoString Technologies, Inc.
    Inventors: Dwayne Dunaway, Elizabeth A. Manrao, Joseph M. Beechem, Rustem Khafizov, Sanghamithra Korukonda, Yi Deng, Dae Kim, Mark Gregory, Margaret Hoang, Matthew Walsh, Gavin Meredith, Mark McElwain, Peter Skene, Cassandra Burke
  • CHEMICAL COMPOSITIONS AND USES THEREOF
    Publication number: 20220282313
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Application
    Filed: March 7, 2022
    Publication date: September 8, 2022
    Inventors: Rustem KHAFIZOV, Dwayne DUNAWAY, Mark GREGORY
  • CHEMICAL COMPOSITIONS AND METHODS OF USING SAME
    Publication number: 20220213532
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Application
    Filed: March 21, 2022
    Publication date: July 7, 2022
    Inventors: Dwayne L. DUNAWAY, Elizabeth A. MANRAO, Joseph M. BEECHEM, Rustem KHAFIZOV, Sanghamithra KORUKONDA, Yi DENG, Dae KIM, Mark GREGORY, Margaret HOANG
  • Chemical compositions and methods of using same
    Patent number: 11279969
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Grant
    Filed: September 4, 2019
    Date of Patent: March 22, 2022
    Assignee: NanoString Technologies, Inc.
    Inventors: Dwayne L. Dunaway, Elizabeth A. Manrao, Joseph M. Beechem, Rustem Khafizov, Sanghamithra Korukonda, Yi Deng, Dae Kim, Mark Gregory, Margaret Hoang
  • Methods and apparatuses for gene purification and imaging
    Patent number: 11098301
    Abstract: The present disclosure is directed to systems, devices and methods for nucleic acid or protein purification and imaging. A system is provided including a cartridge comprising a sample input area configured to hold a sample, comprising a plurality of hybridized complexes comprising a plurality of target molecules each hybridized with probes and a plurality of non-hybridized probes. The cartridge may also include a first binding chamber configured with first magnetic beads to receive and bind the sample, a first elution channel configured to receive the first magnetic beads and elute the sample from the first magnetic beads, a second binding chamber configured with second magnetic beads to receive and bind the sample, a second elution channel configured to receive the second magnetic beads and elute the sample from the second magnetic beads, and a binding area configured to receive the eluted sample and hold molecules for imaging.
    Type: Grant
    Filed: February 11, 2019
    Date of Patent: August 24, 2021
    Assignee: NanoString Technologies, Inc.
    Inventors: Dwayne Dunaway, Rustem Khafizov, Qian Mei, Lucas Dennis, Michael Krouse, Joseph M. Beechem, Isaac Sprague
  • ENZYME- AND AMPLIFICATION-FREE SEQUENCING
    Publication number: 20200010891
    Abstract: The present invention relates to sequencing probes, methods, kits, and apparatuses that provide enzyme-free, amplification-free, and library-free nucleic acid sequencing that has long-read-lengths and with low error rate.
    Type: Application
    Filed: August 1, 2019
    Publication date: January 9, 2020
    Inventors: Joseph M. BEECHEM, Rustem KHAFIZOV
  • CHEMICAL COMPOSITIONS AND METHODS OF USING SAME
    Publication number: 20190390258
    Abstract: The present disclosure relates to chemical compositions, kits, and apparatuses and methods for using these compositions, kits and apparatuses in various assays.
    Type: Application
    Filed: September 4, 2019
    Publication date: December 26, 2019
    Inventors: Dwayne L. DUNAWAY, Elizabeth A. MANRAO, Joseph M. BEECHEM, Rustem KHAFIZOV, Sanghamithra KORUKONDA, Yi DENG, Dae KIM, Mark GREGORY, Margaret HOANG