Abstract: The present invention relates to the modulation of glucocorticoid metabolism. In particular the invention relates to the modulation of the functional activity of the glucocorticoid receptor by 5? reduced metabolic breakdown products of glucocorticoids.

Abstract: The present invention relates to the modulation of glucocorticoid metabolism. In particular the invention relates to the modulation of the functional activity of the glucocorticoid receptor by 5? reduced metabolic breakdown products of glucocorticoids.

Abstract: The invention provides use of an agent which lowers levels of 11?-HSD1 in the manufacture of a composition for the promotion of an atheroprotective lipid profile.

Abstract: A utensil which provides a universal device for removing a bake pan from a hot oven and also inverting the pan to facilitate removal of the cake from the pan. The device is adaptable to a variety of pan dimensions including a tube type bake pan. The device also allows cakes to be removed from pans without damaging the cake itself and is designed to prevent bakers from burning themselves due to frequent handling of hot baking pans. The device includes a flat circular shaped base with an extended handle, which is placed over a hot baking pan top and clamped into position by a slidable spring loaded clamping block. After clamping the device to the top of a hot bake pan, the pan is easily and safely removed from a hot oven, and, while the device is still attached, the pan is then inverted to facilitate removal of the cake from the pan.