Patents by Inventor Ruth E. Bylund

Ruth E. Bylund has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptide derivatives as thrombin inhibitors
    Patent number: 5614499
    Abstract: The invention relates to new competitive inhibitors of thrombin, pharmaceutical compositions containing the compounds as active ingredients, and the use of the compounds as anticoagulants for prophylaxis and treatment of thromboembolic diseases, according to the formula ##STR1## wherein A represents a methylene group, an ethylene group or a propylene group, which may be substituted orA represents --CH.sub.2 --O--CH.sub.2 --, --CH.sub.2 --S--CH.sub.2 --, --CH.sub.2 --SO--CH.sub.2 --, orA represents --CH.sub.2 --O--, --CH.sub.2 --S--, --CH.sub.2 --SO--, with the heteroatom functionality in position 4;n is an integer 2 to 6; andB represents --N(R.sup.6)--C(NH)--NH.sub.2, wherein R.sup.6 is H or a methyl group, orB represents --S--C(NH)--NH.sub.2, or --C(NH)--NH.sub.2.
    Type: Grant
    Filed: December 2, 1992
    Date of Patent: March 25, 1997
    Assignee: Astra Aktiebolag
    Inventors: Ruth E. Bylund, Ann-Catrine E. Teger-Nilsson
  • Peptides derivatives
    Patent number: 5602253
    Abstract: The invention concerns the compound of the formula: ##STR1## and protected forms and salts thereof which serve as starting materials in an improved method of synthesizing serine protease inhibitors. The invention further concerns an improved method for synthesizing serine protease inhibitors which utilizes the compounds.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: February 11, 1997
    Assignee: Aktiebolaget Astra
    Inventors: Karl T. Antonsson, Ruth E. Bylund, Nils O. I. Nilsson