Patents by Inventor Ruth E. Ley

Ruth E. Ley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10925905
    Abstract: Disclosed herein are compositions that have substantially purified Christensenellaceae bacteria, and uses of these compositions to alter the microbiome of an individual. The addition of Christensenellaceae bacteria, such as Christensenella, to the microbiome of an individual can treat or prevent weight gain, reduce body weight, inhibit fat accumulation, reduce excess adiposity, and reduce a high body mass index (BMI), and can also treat or prevent conditions correlating with excess weight and fat and a high BMI, such as insulin sensitivity, metabolic syndrome, excess adiposity, and diabetes.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: February 23, 2021
    Assignee: CORNELL UNIVERSITY
    Inventors: Ruth E. Ley, Julia Goodrich, Jillian Waters
  • Publication number: 20190175668
    Abstract: Disclosed herein are compositions that have substantially purified Christensenellaceae bacteria, and uses of these compositions to alter the microbiome of an individual. The addition of Christensenellaceae bacteria, such as Christensenella, to the microbiome of an individual can treat or prevent weight gain, reduce body weight, inhibit fat accumulation, reduce excess adiposity, and reduce a high body mass index (BMI), and can also treat or prevent conditions correlating with excess weight and fat and a high BMI, such as insulin sensitivity, metabolic syndrome, excess adiposity, and diabetes.
    Type: Application
    Filed: December 12, 2018
    Publication date: June 13, 2019
    Inventors: Ruth E. LEY, Julia Goodrich, Jillian Waters
  • Patent number: 10206958
    Abstract: Disclosed herein are compositions that have substantially purified Christensenellaceae bacteria, and uses of these compositions to alter the microbiome of an individual. The addition of Christensenellaceae bacteria, such as Christensenella, to the microbiome of an individual can treat or prevent weight gain, reduce body weight, inhibit fat accumulation, reduce excess adiposity, and reduce a high body mass index (BMI), and can also treat or prevent conditions correlating with excess weight and fat and a high BMI, such as insulin sensitivity, metabolic syndrome, excess adiposity, and diabetes.
    Type: Grant
    Filed: April 23, 2015
    Date of Patent: February 19, 2019
    Assignee: CORNELL UNIVERSITY
    Inventors: Ruth E. Ley, Julia Goodrich, Jillian Waters
  • Patent number: 9885089
    Abstract: High levels of bacterial flagella in a sample such as a gastrointestinal sample and/or low levels of anti-flagella antibodies serve as an indication for metabolic syndrome (such as insulin resistance, hypertension, elevated cholesterol, increased risk for blood clotting, and obesity) with highest levels of adiposity. An intervention that reduces the level and/or activity of flagella in the gastrointestinal tract can mitigate the severity of metabolic syndrome or in protecting against the development of metabolic syndrome.
    Type: Grant
    Filed: March 5, 2013
    Date of Patent: February 6, 2018
    Assignee: CORNELL UNIVERSITY
    Inventors: Ruth E. Ley, Tyler Cullender
  • Publication number: 20170042948
    Abstract: Disclosed herein are compositions that have substantially purified Christensenellaceae bacteria, and uses of these compositions to alter the microbiome of an individual. The addition of Christensenellaceae bacteria, such as Christensenella, to the microbiome of an individual can treat or prevent weight gain, reduce body weight, inhibit fat accumulation, reduce excess adiposity, and reduce a high body mass index (BMI), and can also treat or prevent conditions correlating with excess weight and fat and a high BMI, such as insulin sensitivity, metabolic syndrome, excess adiposity, and diabetes.
    Type: Application
    Filed: April 23, 2015
    Publication date: February 16, 2017
    Applicant: CORNELL UNIVERSITY
    Inventors: Ruth E. LEY, Julia GOODRICH, Jillian WATERS
  • Publication number: 20150050293
    Abstract: High levels of bacterial flagella in a sample such as a gastrointestinal sample and/or low levels of anti-flagella antibodies serve as an indication for metabolic syndrome (such as insulin resistance, hypertension, elevated cholesterol, increased risk for blood clotting, and obesity) with highest levels of adiposity. An intervention that reduces the level and/or activity of flagella in the gastrointestinal tract can mitigate the severity of metabolic syndrome or in protecting against the development of metabolic syndrome.
    Type: Application
    Filed: March 5, 2013
    Publication date: February 19, 2015
    Applicant: CORNELL UNIVERSITY
    Inventors: Ruth E. Ley, Tyler Cullender
  • Publication number: 20140093478
    Abstract: The present invention relates to the gut microbiome as a biomarker and therapeutic target for energy harvesting, weight loss or gain, and/or obesity in a subject. In particular, the invention provides methods of altering and monitoring the relative abundance of Bacteroides and Firmicutes in the gut microbiome of a subject.
    Type: Application
    Filed: October 9, 2013
    Publication date: April 3, 2014
    Inventors: Peter J. Turnbaugh, Ruth E. Ley, Michael A. Mahowld, Jeffrey I. Gordon
  • Publication number: 20100172874
    Abstract: The present invention relates to the gut microbiome as a biomarker and therapeutic target for energy harvesting, weight loss or gain, and/or obesity in a subject. In particular, the invention provides methods of altering and monitoring the relative abundance of Bacteroides and Firmicutes in the gut microbiome of a subject.
    Type: Application
    Filed: December 10, 2007
    Publication date: July 8, 2010
    Applicant: THE WASHINGTON UNIVERSITY
    Inventors: Peter J. Turnbaugh, Ruth E. Ley, Michael A. Mahowald, Jeffrey I. Gordon