Patents by Inventor Ruth HUNEGNAW

Ruth HUNEGNAW has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds inhibiting Nef-calnexin interaction
    Patent number: 11561217
    Abstract: The invention relates to compounds and methods for restoring or preserving cholesterol efflux in a cell infected with Human Immunodeficiency Virus (HIV) by preventing or decreasing an interaction between Negative Regulatory Factor (Nef) protein and Calnexin protein, and methods for screening for such compounds.
    Type: Grant
    Filed: August 24, 2021
    Date of Patent: January 24, 2023
    Assignee: THE GEORGE WASHINGTON UNIVERSITY
    Inventors: Alexei Adzhubei, Michael Bukrinsky, Ruth Hunegnaw
  • COMPOUNDS INHIBITING NEF-CALNEXIN INTERACTION
    Publication number: 20210405029
    Abstract: The invention relates to compounds and methods for restoring or preserving cholesterol efflux in a cell infected with Human Immunodeficiency Virus (HIV) by preventing or decreasing an interaction between Negative Regulatory Factor (Nef) protein and Calnexin protein, and methods for screening for such compounds.
    Type: Application
    Filed: August 24, 2021
    Publication date: December 30, 2021
    Inventors: Alexei ADZHUBEI, Michael BUKRINSKY, Ruth HUNEGNAW
  • Compounds inhibiting Nef-calnexin interaction
    Patent number: 11131661
    Abstract: The invention relates to compounds and methods for restoring or preserving cholesterol efflux in a cell infected with Human Immunodeficiency Virus (HIV) by preventing or decreasing an interaction between Negative Regulatory Factor (Nef) protein and Calnexin protein, and methods for screening for such compounds.
    Type: Grant
    Filed: April 6, 2020
    Date of Patent: September 28, 2021
    Assignee: THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION
    Inventors: Alexei Adzhubei, Michael Bukrinsky, Ruth Hunegnaw
  • COMPOUNDS INHIBITING NEF-CALNEXIN INTERACTION
    Publication number: 20200340977
    Abstract: The invention relates to compounds and methods for restoring or preserving cholesterol efflux in a cell infected with Human Immunodeficiency Virus (HIV) by preventing or decreasing an interaction between Negative Regulatory Factor (Nef) protein and Calnexin protein, and methods for screening for such compounds.
    Type: Application
    Filed: April 6, 2020
    Publication date: October 29, 2020
    Applicant: THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION
    Inventors: Alexei ADZHUBEI, Michael BUKRINSKY, Ruth HUNEGNAW
  • Compounds inhibiting Nef-calnexin interaction
    Patent number: 10684274
    Abstract: The invention relates to compounds and methods for restoring or preserving cholesterol efflux in a cell infected with Human Immunodeficiency Virus (HIV) by preventing or decreasing an interaction between Negative Regulatory Factor (Nef) protein and Calnexin protein, and methods for screening for such compounds.
    Type: Grant
    Filed: January 12, 2017
    Date of Patent: June 16, 2020
    Assignee: THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONLLY CHARTERED NOT-FOR-PROFIT CORPORATION
    Inventors: Alexei Adzhubei, Michael Bukrinsky, Ruth Hunegnaw
  • COMPOUNDS INHIBITING NEF-CALNEXIN INTERACTION
    Publication number: 20190033297
    Abstract: The invention relates to compounds and methods for restoring or preserving cholesterol efflux in a cell infected with Human Immunodeficiency Virus (HIV) by preventing or decreasing an interaction between Negative Regulatory Factor (Nef) protein and Calnexin protein, and methods for screening for such compounds.
    Type: Application
    Filed: January 12, 2017
    Publication date: January 31, 2019
    Applicants: CORPORATION
    Inventors: Alexei ADZHUBEI, Michael BUKRINSKY, Ruth HUNEGNAW