Patents by Inventor Ruth Jostock

Ruth Jostock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted Benzamide Compounds
    Publication number: 20120071461
    Abstract: Substituted benzamide compounds corresponding to formula (I) in which R5, R6, R7, R8, a, b, c, d, t, D and X have defined meanings, a process for their preparation, pharmaceutical compositions comprising such compounds, and a method of using such compounds to treat pain and other conditions mediated at least in part via the bradykinin 1 receptor.
    Type: Application
    Filed: September 22, 2011
    Publication date: March 22, 2012
    Applicant: GRUENENTHAL GmbH
    Inventors: Melanie Reich, Stefan Schunk, Ruth Jostock, Jean De Vry, Christa Kneip, Tieno Germann, Michael Engels
  • Substituted Tetrahydropyrrolopyrazine Compounds
    Publication number: 20120058999
    Abstract: Tetrahydropyrrolopyrazine compounds, methods for their preparation, pharmaceutical compositions containing such compounds, and a method of using such compounds for the treatment of pain and other conditions mediated at least partially by Bradykinin 1 receptors (B1R).
    Type: Application
    Filed: September 2, 2011
    Publication date: March 8, 2012
    Applicant: Gruenenthal GmbH
    Inventors: Melanie REICH, Stefan SCHUNK, Stefan OBERBOERSCH, Ruth JOSTOCK, Tieno GERMANN, Michael ENGELS
  • Substituted sulfonamide compounds
    Patent number: 8124624
    Abstract: Substituted sulfonamide compounds corresponding to formula I: a process for their preparation, pharmaceutical compositions comprising such compounds, and the use of such substituted sulfonamide compounds in pharmaceutical compositions for the treatment of pain or other disorders or diseases that are mediated at least in part by B1R receptors.
    Type: Grant
    Filed: April 8, 2009
    Date of Patent: February 28, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Stefan Oberboersch, Melanie Reich, Stefan Schunk, Michael Engels, Ruth Jostock, Tieno Germann, Sabine Hees
  • Substituted disulfonamide compounds
    Patent number: 8119805
    Abstract: Substituted disulfonamide compounds corresponding to formula I: In which R1, R2, R3, R4a, R4b, R5a, R5b, R8, R9a, R9b, R10, R11, a, b, s, t and A have defined meanings, pharmaceutical compositions containing one or more such compounds, processes for preparing such compounds, and a method of using such compounds for the treatment or inhibition of pain and/or other conditions mediated by the bradykinin receptor 1 (BR1).
    Type: Grant
    Filed: November 6, 2009
    Date of Patent: February 21, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Melanie Reich, Stefan Schunk, Ruth Jostock, Sabine Hees, Tieno Germann, Michael Franz-Martin Engels
  • Substituted sulfonamide compounds
    Patent number: 8119633
    Abstract: Substituted sulfonamide compounds corresponding to formula I pharmaceutical compositions comprising them, a process for preparing them, and the use of such compounds to treat or inhibit pain and other disorders or disease states.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: February 21, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Beatrix Merla, Stefan Oberboersch, Melanie Reich, Bernd Sundermann, Werner Englberger, Timo Struenker, Ruth Jostock, Sabine Hees, Edward Bijsterveld, Fritz Theil, Heinz Graubaum
  • Substituted spiro-compounds and the use thereof for producing medicaments
    Patent number: 7981883
    Abstract: The present invention relates to substituted spiro compounds, to processes for preparing them, to medicaments comprising these compounds and to the use of these compounds for producing medicaments.
    Type: Grant
    Filed: May 17, 2006
    Date of Patent: July 19, 2011
    Assignee: Gruenenthal GmbH
    Inventors: Robert Frank, Ruth Jostock, Melanie Reich, Gregor Bahrenberg, Hans Schick, Helmut Sonnenschein
  • Benzo[d]isoxazol-3-yl-amine compounds and their use as vanilloid receptor ligands
    Patent number: 7977360
    Abstract: The present invention relates to substituted benzo[d]isoxazol-3-yl-amine compounds, methods for their production, medicaments containing these compounds and the use of these compounds to produce medicaments.
    Type: Grant
    Filed: May 18, 2006
    Date of Patent: July 12, 2011
    Assignee: Gruenenthal GmbH
    Inventors: Robert Frank, Beatrix Merla, Melanie Reich, Ruth Jostock
  • Substituted benzo-condensed cyclohexanone derivatives and the use thereof for medicament production
    Patent number: 7973072
    Abstract: The invention relates to substituted benzo-condensed cyclohexanone derivatives, to a method for the production thereof, to medicaments containing said derivatives and to the use of the inventive compounds for producing medicaments.
    Type: Grant
    Filed: May 17, 2006
    Date of Patent: July 5, 2011
    Assignee: Gruenenthal GmbH
    Inventors: Robert Frank, Michael Przewosny, Ruth Jostock
  • Substituted Benzimidazoles, Benzothiazoles and Benzoxazoles
    Publication number: 20110009382
    Abstract: Substituted benzimidazoles, benzothiazoles and benzoxazoles, processes for their preparation, pharmaceutical compostions containing these compounds and the use of these compounds for treating or inhibiting disorders or disease states mediated at least in part by bradykinin receptor 1 (BR1).
    Type: Application
    Filed: June 7, 2010
    Publication date: January 13, 2011
    Applicant: Gruenenthal GmbH
    Inventors: Stefan Schunk, Melanie Reich, Michael Engels, Tieno Germann, Jean De Vry, Ruth Jostock, Sabine Hees
  • Substituted benzo-condensed cycloheptanone derivatives and their use for producing drugs
    Patent number: 7858613
    Abstract: The invention relates to substituted benzo-condensed cycloheptanone derivatives, to methods for producing them, to drugs containing said compounds and to the use of said compounds for producing drugs.
    Type: Grant
    Filed: May 17, 2006
    Date of Patent: December 28, 2010
    Assignee: Gruenenthal GmbH
    Inventors: Claudia Hinze, Robert Frank, Ruth Jostock, Klaus Schiene, Michael Haurand, Hagen-Heinrich Hennies
  • Substituted Sulfonamide Compounds
    Publication number: 20100324009
    Abstract: Substituted sulfonamide derivatives, a process for their preparation, pharmaceutical compositions containing these compounds, and to the use of substituted sulfonamide derivatives in the treatment or inhibition of pain and/or various disorders or disease states.
    Type: Application
    Filed: August 24, 2010
    Publication date: December 23, 2010
    Applicant: Gruenenthal GmbH
    Inventors: Stefan OBERBOERSCH, Melanie Reich, Stefan Schunk, Sabine Hees, Ruth Jostock, Michael Franz-Martin Engels, Achim Kless, Thomas Christoph, Klaus Schiene, Tieno Germann, Edward Bijsterveld
  • Substituted Sulfonamide Compounds
    Publication number: 20100317644
    Abstract: Substituted sulfonamide derivatives, a process for their preparation, pharmaceutical compositions containing these compounds, and to the use of substituted sulfonamide derivatives in the treatment or inhibition of pain and/or various disorders or disease states.
    Type: Application
    Filed: August 24, 2010
    Publication date: December 16, 2010
    Applicant: Gruenenthal GmbH
    Inventors: Stefan OBERBOERSCH, Melanie Reich, Stefan Schunk, Sabine Hees, Ruth Jostock, Michael Franz-Martin Engels, Achim Kless, Thomas Christoph, Klaus Schiene, Tieno Germann, Edward Bijsterveld
  • Substituted Spiro-amide Compounds
    Publication number: 20100249095
    Abstract: Substituted spiro-amide compounds corresponding to formula I in which R5 through R8, D, X, Y and Z have defined meanings, processes for preparing such spiro-amide compounds, pharmaceutical compositions containing such compounds, and methods of using such spiro-amide compounds for treating and/or inhibiting disorders or disease states mediated at least in part by the bradykinin 1 receptor.
    Type: Application
    Filed: March 24, 2010
    Publication date: September 30, 2010
    Applicant: Gruenenthal GmbH
    Inventors: Stefan Schunk, Melanie Reich, Stefan Oberboersch, Michael Engels, Tieno Germann, Ruth Jostock, Christa Kneip
  • Sulfonylated Tetrahydroazolopyrazines and their Use as Pharmaceuticals
    Publication number: 20100234387
    Abstract: Sulfonylated tetrahydroazolopyrazine compounds corresponding to the formula I wherein R1, R2a, R2b, R3a, R3b, R4, R8, R9a, R9b, R10, R11, A, B, W1, W2 and W3 have the meanings defined herein, pharmaceutical compositions containing such compounds, a method for the preparation of such compounds, and the use of such compounds for treating or inhibiting various types of pain and/or other conditions mediated at least in part by the bradykinin 1 receptor (B1R).
    Type: Application
    Filed: March 4, 2010
    Publication date: September 16, 2010
    Applicant: Gruenethal GmbH
    Inventors: Beatrix MERLA, Stefan Oberboersch, Melanie Reich, Stefan Schunk, Ruth Jostock, Sabine Hees, Michael Engels, Tieno Germann, Edward Bijsterveld
  • Substituted Spiroamide Compounds
    Publication number: 20100234340
    Abstract: Substituted spiroamide compounds corresponding to formula (I): wherein A, B, Q1, Q2, Q3, Q4, R1, R8, R9a, R9b, R12, R13, R200 and R210 have defined meanings, processes for their preparation, pharmaceutical compositions containing such compounds, and the use of such compounds for treating or inhibiting pain or other conditions mediated at least in part by the bradykinin 1 receptor (B1R).
    Type: Application
    Filed: February 5, 2010
    Publication date: September 16, 2010
    Applicant: Gruenenthal GmbH
    Inventors: Stefan Schunk, Melanie Reich, Michael Engels, Tieno Germann, Ruth Jostock, Sabine Hees
  • Substituted Indole Compounds
    Publication number: 20100222324
    Abstract: Substituted indole compounds corresponding to the formula I: In which R8, R9a, R9b, R10, R11, R200, R210, A, D, T, q, s and t have defined meanings, processes for the preparation thereof, pharmaceutical compositions containing such compounds and the use of substituted indole compounds for the treatment or inhibition of pain and other conditions which are at least partly mediated by Bradykinin 1 receptors (B1R).
    Type: Application
    Filed: February 3, 2010
    Publication date: September 2, 2010
    Applicant: Gruenenthal GmbH
    Inventors: Stefan Schunk, Melanie Reich, Michael Engels, Tieno Germann, Ruth Jostock, Sabine Hees
  • Substituted Pyrimidine and Triazine Compounds
    Publication number: 20100173889
    Abstract: Substituted pyrimidine and triazine compounds corresponding to formula I wherein R1, R2, R3, R4a, R4b, R5a, R5b, R7, R8, R9a, R9b, R10, R11, A, a, b, s, t, V, W1, W2 and W3 have defined meanings, pharmaceutical compositions comprising such compounds, a process for preparing such compounds, and the use of such compounds and compositions to treat or inhibit pain and/or other disorders or disease states.
    Type: Application
    Filed: October 23, 2009
    Publication date: July 8, 2010
    Applicant: GRUENENTHAL GmbH
    Inventors: Stefan Schunk, Melanie Reich, Kamila Hennig, Michael Engels, Tieno Germann, Ruth Jostock, Sabine Hees
  • Substituted Disulfonamide Compounds
    Publication number: 20100152158
    Abstract: Substituted disulfonamide compounds corresponding to formula I: In which R1, R2, R3, R4a, R4b, R5a, R5b, R8, R9a, R9b, R10, R11, a, b, s, t and A have defined meanings, pharmaceutical compositions containing one or more such compounds, processes for preparing such compounds, and a method of using such compounds for the treatment or inhibition of pain and/or other conditions mediated by the bradykinin receptor 1 (BR1).
    Type: Application
    Filed: November 6, 2009
    Publication date: June 17, 2010
    Applicant: GRUENENTHAL GmbH
    Inventors: Melanie REICH, Stefan Schunk, Ruth Jostock, Sabine Hees, Tieno Germann, Michael Franz-Martin Engels
  • Substituted Spiroamine Compounds
    Publication number: 20100113417
    Abstract: Substituted spiroamine compounds corresponding to the formula (I) In which m, n, o, p, Q, r, s, t, R1, R2, R3, R4a, R4b, R5a, R5b, R6a, R6b, R7, R8, R9, R10 and R11 have defined meanings; a process for the preparation of such compounds, pharmaceutical compositions containing such compounds and the use of substituted spiroamines for the treatment or inhibition of pain and/or other conditions mediated by the bradykinin 1 receptor.
    Type: Application
    Filed: October 29, 2009
    Publication date: May 6, 2010
    Applicant: GRUENENTHAL GmbH
    Inventors: Melanie REICH, Stefan Oberboersch, Stefan Schunk, Ruth Jostock, Sabine Hees, Michael Engels
  • Substituted Sulfonamide Compounds
    Publication number: 20090298812
    Abstract: Substituted sulfonamide compounds corresponding to the formula I processes for the preparation thereof, pharmaceutical compositions containing these compounds and the use of substituted sulfonamide compounds for the preparation of pharmaceutical compositions for treating pain and other conditions at least partly mediated via the bradykinin 1 receptor.
    Type: Application
    Filed: March 4, 2009
    Publication date: December 3, 2009
    Applicant: Gruenenthal GmbH
    Inventors: Stefan Oberboersch, Ruth Jostock, Klaus Schiene, Jean De Vry, Tieno Germann, Sabine Hees, Stefan Schunk, Melanie Reich