Patents by Inventor Ruth Ladenstein

Ruth Ladenstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230340148
    Abstract: The present invention relates to a method for treating a GD2 positive cancer by administering a preparation comprising an anti-GD2 antibody to a patient as a continuous intravenous infusion over 24 hours per day.
    Type: Application
    Filed: September 19, 2022
    Publication date: October 26, 2023
    Applicant: APEIRON BIOLOGICS AG
    Inventors: Hans LOIBNER, Manfred SCHUSTER, Evelyne JANZEK-HAWLAT, Susanne WIEDERKUM, Bernhard PEBALL, Stefan STRANNER, Oliver MUTSCHLECHNER, Franz GROISS, Ruth LADENSTEIN, Holger LODE
  • Publication number: 20230295339
    Abstract: A method of treating a newly diagnosed neuroblastoma in a patient by administering chimeric anti-GD2 antibody dinutuximab beta to the patient in combination with induction chemotherapy. The chimeric anti-GD2 antibody dinutuximab beta is administered at a cumulative dose of up to 500 mg/m2, and/or in a dose of up to 100 mg/m2 per cycle during one or more cycles of induction chemotherapy, and/or at a treatment density of up to 5 mg/m2/day.
    Type: Application
    Filed: July 6, 2021
    Publication date: September 21, 2023
    Applicant: EUSA PHARMA (UK) LIMITED
    Inventors: Holger Nikolaus LODE, Ruth LADENSTEIN
  • Patent number: 11597775
    Abstract: The present invention relates to preparations and methods for treating a GD2 positive cancer by administering a preparation comprising a chimeric or humanized anti-GD2 antibody to a patient, wherein the patient is not concomitantly treated with Interleukin-2 (IL-2 wherein a GD2 positive cancer is treated in the patient. Furthermore, the invention relates to preparations and methods for the treatment of a GD2 positive cancer in a patient, wherein a preparation comprising an anti-GD2 antibody is administered to the patient as a continuous infusion, without concomitantly administering IL-2. The present invention further relates to preparations and methods for the treatment of a GD2 positive cancer in a patient, wherein the one or more anti-GD2 antibody treatment periods is/are preceded, accompanied, and/or followed by one or more treatment periods with a retinoid.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: March 7, 2023
    Assignee: APEIRON BIOLOGICS AG
    Inventors: Hans Loibner, Oliver Mutschlechner, Ruth Ladenstein, Isabel Klier
  • Patent number: 11492412
    Abstract: A method of treating a high-risk neuroblastoma in a patient is described.
    Type: Grant
    Filed: March 3, 2021
    Date of Patent: November 8, 2022
    Assignee: APEIRON BIOLOGICS AG
    Inventors: Hans Loibner, Oliver Mutschlechner, Ruth Ladenstein, Isabel Klier
  • Patent number: 11447565
    Abstract: The present invention relates to a method for treating a GD2 positive cancer by administering a preparation comprising an anti-GD2 antibody to a patient as a continuous intravenous infusion over 24 hours per day.
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: September 20, 2022
    Assignee: APEIRON BIOLOGICS AG
    Inventors: Hans Loibner, Manfred Schuster, Evelyne Janzek-Hawlat, Susanne Wiederkum, Bernhard Peball, Stefan Stranner, Oliver Mutschlechner, Franz Groiss, Ruth Ladenstein, Holger Lode
  • Publication number: 20210221909
    Abstract: A method of treating a high-risk neuroblastoma in a patient is described.
    Type: Application
    Filed: March 3, 2021
    Publication date: July 22, 2021
    Applicant: APEIRON BIOLOGICS AG
    Inventors: Hans LOIBNER, Oliver MUTSCHLECHNER, Ruth LADENSTEIN, Isabel KLIER
  • Patent number: 10995147
    Abstract: A method of treating a high-risk neuroblastoma in a patient is described.
    Type: Grant
    Filed: July 6, 2020
    Date of Patent: May 4, 2021
    Assignee: APEIRON BIOLOGICS AG
    Inventors: Hans Loibner, Oliver Mutschlechner, Ruth Ladenstein, Isabel Klier
  • Publication number: 20200332021
    Abstract: A method of treating a high-risk neuroblastoma in a patient is described.
    Type: Application
    Filed: July 6, 2020
    Publication date: October 22, 2020
    Applicant: APEIRON BIOLOGICS AG
    Inventors: Hans LOIBNER, Oliver MUTSCHLECHNER, Ruth LADENSTEIN, Isabel KLIER
  • Publication number: 20200055953
    Abstract: Preparations and methods for treating a GD2 positive cancer by administering a preparation comprising an anti-GD2 antibody to a patient, wherein the patient is not concomitantly treated with Interleukin-2 (IL-2), and wherein one or more treatment periods with the antibody may be preceded, accompanied, and/or followed by one or more treatment periods with a retinoid.
    Type: Application
    Filed: April 4, 2019
    Publication date: February 20, 2020
    Inventors: Hans Loibner, Oliver Mutschlechner, Ruth Ladenstein, Isabel Klier
  • Patent number: 10294305
    Abstract: Preparations and methods for treating a GD2 positive cancer by administering a preparation comprising an anti-GD2 antibody to a patient, wherein the patient is not concomitantly treated with Interleukin-2 (IL-2), and wherein one or more treatment periods with the antibody may be preceded, accompanied, and/or followed by one or more treatment periods with a retinoid.
    Type: Grant
    Filed: February 18, 2014
    Date of Patent: May 21, 2019
    Assignee: APEIRON BIOLOGICS AG
    Inventors: Hans Loibner, Oliver Mutschlechner, Ruth Ladenstein, Isabel Klier
  • Publication number: 20180258183
    Abstract: The present invention relates to preparations and methods for treating a GD2 positive cancer by administering a preparation comprising a chimeric or humanized anti-GD2 antibody to a patient, wherein the patient is not concomitantly treated with Interleukin-2 (IL-2 wherein a GD2 positive cancer is treated in the patient. Furthermore, the invention relates to preparations and methods for the treatment of a GD2 positive cancer in a patient, wherein a preparation comprising an anti-GD2 antibody is administered to the patient as a continuous infusion, without concomitantly administering IL-2. The present invention further relates to preparations and methods for the treatment of a GD2 positive cancer in a patient, wherein the one or more anti-GD2 antibody treatment periods is/are preceded, accompanied, and/or followed by one or more treatment periods with a retinoid.
    Type: Application
    Filed: November 28, 2017
    Publication date: September 13, 2018
    Applicant: APEIRON BIOLOGICS AG
    Inventors: Hans LOIBNER, Oliver MUTSCHLECHNER, Ruth LADENSTEIN, Isabel KLIER
  • Publication number: 20180134801
    Abstract: The present invention relates to a method for treating a GD2 positive cancer by administering a preparation comprising an anti-GD2 antibody to a patient as a continuous intravenous infusion over 24 hours per day.
    Type: Application
    Filed: September 11, 2017
    Publication date: May 17, 2018
    Applicant: APEIRON BIOLOGICS AG
    Inventors: Hans LOIBNER, Manfred SCHUSTER, Evelyne JANZEK-HAWLAT, Susanne WIEDERKUM, Bernhard PEBALL, Stefan STRANNER, Oliver MUTSCHLECHNER, Franz GROISS, Ruth LADENSTEIN, Holger LODE
  • Patent number: 9840566
    Abstract: The present invention relates to preparations and methods for treating a GD2 positive cancer by administering a preparation comprising a chimeric or humanized anti-GD2 antibody to a patient, wherein the patient is not concomitantly treated with interleukin-2 (IL-2 wherein a GD2 positive cancer is treated in the patient. Furthermore, the invention relates to preparations and methods for the treatment of a GD2 positive cancer in a patient, wherein a preparation comprising an anti-GD2 antibody is administered to the patient as a continuous infusion, without concomitantly administering IL-2. The present invention further relates to preparations and methods for the treatment of a GD2 positive cancer in a patient, wherein the one or more anti-GD2 antibody treatment periods is/are preceded, accompanied, and/or followed by one or more treatment periods with a retinoid.
    Type: Grant
    Filed: November 21, 2014
    Date of Patent: December 12, 2017
    Assignee: APEIRON BIOLOGICS AG
    Inventors: Hans Loibner, Oliver Mutschlechner, Ruth Ladenstein, Isabel Klier
  • Patent number: 9777068
    Abstract: The present invention relates to a method for treating a GD2 positive cancer by administering a preparation comprising an anti-GD2 antibody to a patient as a continuous intravenous infusion over 24 hours per day.
    Type: Grant
    Filed: July 31, 2012
    Date of Patent: October 3, 2017
    Assignee: APEIRON BIOLOGICS AG
    Inventors: Hans Loibner, Manfred Schuster, Evelyne Janzek-Hawlat, Susanne Wiederkum, Bernhard Peball, Stefan Stranner, Oliver Mutschlechner, Franz Groiss, Ruth Ladenstein, Holger Lode
  • Publication number: 20160304620
    Abstract: The present invention relates to preparations and methods for treating a GD2 positive cancer by administering a preparation comprising a chimeric or humanized anti-GD2 antibody to a patient, wherein the patient is not concomitantly treated with interleukin-2 (IL-2 wherein a GD2 positive cancer is treated in the patient. Furthermore, the invention relates to preparations and methods for the treatment of a GD2 positive cancer in a patient, wherein a preparation comprising an anti-GD2 antibody is administered to the patient as a continuous infusion, without concomitantly administering IL-2. The present invention further relates to preparations and methods for the treatment of a GD2 positive cancer in a patient, wherein the one or more anti-GD2 antibody treatment periods is/are preceded, accompanied, and/or followed by one or more treatment periods with a retinoid.
    Type: Application
    Filed: November 21, 2014
    Publication date: October 20, 2016
    Applicant: APEIRON BIOLOGICS AG
    Inventors: Hans LOIBNER, Oliver MUTSCHLECHNER, Ruth LADENSTEIN, Isabel KLIER
  • Publication number: 20150139942
    Abstract: The present invention relates to a method for treating a GD2 positive cancer by administering a preparation comprising an anti-GD2 antibody to a patient as a continuous intravenous infusion over 24 hours per day.
    Type: Application
    Filed: July 31, 2012
    Publication date: May 21, 2015
    Applicant: APEIRON BIOLOGICS AG
    Inventors: Hans Loibner, Manfred Schuster, Evelyne Janzek-Hawlat, Susanne Wiederkum, Bernhard Peball, Stefan Stranner, Oliver Mutschlechner, Franz Groiss, Ruth Ladenstein, Holger Lode
  • Publication number: 20140170155
    Abstract: Preparations and methods for treating a GD2 positive cancer by administering a preparation comprising an anti-GD2 antibody to a patient, wherein the patient is not concomitantly treated with Interleukin-2 (IL-2), and wherein one or more treatment periods with the antibody may be preceded, accompanied, and/or followed by one or more treatment periods with a retinoid.
    Type: Application
    Filed: February 18, 2014
    Publication date: June 19, 2014
    Applicant: APEIRON BIOLOGICS AG
    Inventors: Hans Loibner, Oliver Mutschlechner, Ruth Ladenstein, Isabel Klier