Patents by Inventor Ruth M. Starzyk

Ruth M. Starzyk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transferrin receptor specific ligand-neuropharmaceutical agent fusion proteins
    Patent number: 5977307
    Abstract: The present invention pertains to a method for delivering a neuropharmaceutical agent across the blood brain barrier to the brain of a host. The method comprises administering to the host a therapeutically effective amount of a ligand-neuropharmaceutical agent fusion protein wherein the ligand is reactive with a brain capillary endothelial cell receptor. Other aspects of this invention include a delivery system comprising a ligand reactive with a brain capillary endothelial cell receptor which has formed a fusion protein with a neuropharmaceutical agent. The fusion proteins are also aspects of this invention.
    Type: Grant
    Filed: February 13, 1996
    Date of Patent: November 2, 1999
    Assignees: Alkermes, Inc., The Regents of the University of California
    Inventors: Phillip M. Friden, Ruth M. Starzyk, Sherie L. Morrison, Eun-Chung Park, John P. McGrath
  • Transferrin neuropharmaceutical agent fusion protein
    Patent number: 5672683
    Abstract: The present invention pertains to a method for delivering a neuropharmaceutical agent across the blood brain barrier to the brain of a host. The method comprises administering to the host a therapeutically effective amount of a ligand-neuropharmaceutical agent fusion protein wherein the ligand is reactive with a brain capillary endothelial cell receptor. Other aspects of this invention include a delivery system comprising a ligand reactive with a brain capillary endothelial cell receptor which has formed a fusion protein with a neuropharmaceutical agent. The fusion proteins are also aspects of this invention.
    Type: Grant
    Filed: July 16, 1993
    Date of Patent: September 30, 1997
    Assignees: Alkermes, Inc., The Regents of the University of California
    Inventors: Phillip M. Friden, Ruth M. Starzyk, Sherie L. Morrison, Eun-Chung Park