Patents by Inventor Ruth March

Ruth March has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of polymorphisms in human OATP-C associated with an effect on statin pharmacokinetics in humans in statin therapy
    Patent number: 7700277
    Abstract: This invention relates to use of polymorphisms in human OATP-C in statin therapy because they are associated with an effect on statin pharmacokinetics (PK) in humans, especially rosuvastatin pharmacokinetics. The invention also relates to the use of OATP-C polymorphisms in predicting the efficacy and safety of statins, whose uptake in to the liver is mediated by OATP-C, especially rosuvastatin.
    Type: Grant
    Filed: July 26, 2004
    Date of Patent: April 20, 2010
    Assignee: AstraZeneca AB
    Inventors: Helen Jean Ambrose, Ruth March
  • Method
    Publication number: 20070031838
    Abstract: This invention relates to use of polymorphisms in human OATP-C in statin therapy because they are associated with an effect on statin pharmacokinetics (PK) in humans, especially rosuvastatin pharmacokinetics. The invention also relates to the use of OATP-C polymorphisms in predicting the efficacy and safety of statins, whose uptake in to the liver is mediated by OATP-C, especially rosuvastatin.
    Type: Application
    Filed: July 26, 2004
    Publication date: February 8, 2007
    Inventors: Helen Ambrose, Ruth March